89-018-870

dystrophin, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-018-870-Each-of-1 In Stock ₹ 50,993.76

89-018-870 - Each of 1

₹ 50,993.76

In Stock

Quantity

1

Base Price: ₹ 50,993.76

GST (18%): ₹ 9,178.877

Total Price: ₹ 60,172.637

Antigen

dystrophin

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against a full-length human DMD protein.

Gene

DMD

Gene Alias

BMD/CMD3B/DXS142/DXS164/DXS206/DXS230/DXS239/DXS268/DXS269/DXS270/DXS272

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Gene ID (Entrez)

1756

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_004016.1

Gene Symbols

DMD

Immunogen

DMD (NP_004007.1, 1 a.a. ∼ 635 a.a) full-length human protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

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Description

  • The dystrophin gene is the largest gene found in nature, measuring 2.4Mb
  • The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies
  • DMD is a recessive, fatal, X-linked disorder occurring at a frequency of about 1 in 3500 new-born males
  • BMD is a milder allelic form
  • In general, DMD patients carry mutations which cause premature translation termination (nonsense or frame shift mutations), while in BMD patients dystrophin is reduced either in molecular weight (derived from in-frame deletions) or in expression level
  • The dystrophin gene is highly complex, containing at least eight independent, tissue-specific promoters and two polyA-addition sites
  • Furthermore, dystrophin RNA is differentially spliced, producing a range of different transcripts, encoding a large set of protein isoforms
  • Dystrophin (as encoded by the Dp427 transcripts) is a large, rod-like cytoskeletal protein which is found at the inner surface of muscle fibers
  • Dystrophin is part of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton (F-actin) and the extra-cellular matrix
  • [provided by RefSeq Sequence: MREQLKGHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAMESLVSVMTDEEGAE

Compare Similar Items

Show Difference

Img

Abnova Corporation

89-018-870

--


Antigen:
dystrophin

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human DMD protein.

Gene:
DMD

Gene Alias:
BMD/CMD3B/DXS142/DXS164/DXS206/DXS230/DXS239/DXS268/DXS269/DXS270/DXS272

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
1756

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_004016.1

Gene Symbols:
DMD

Immunogen:
DMD (NP_004007.1, 1 a.a. ∼ 635 a.a) full-length human protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

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Abnova Corporation

89-018-878

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Antigen:
mitogen-activated protein kinase kinase kinase 14

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human MAP3K14 protein.

Gene:
MAP3K14

Gene Alias:
FTDCR1B/HS/HSNIK/NIK

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
9020

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

Applications:
Immunofluorescence, In situ PLA, Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
BC035576.1

Gene Symbols:
MAP3K14

Immunogen:
MAP3K14 (NP_003945.2, 1 a.a. ∼ 947 a.a) full-length human protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Img

Abnova Corporation

89-018-880

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Antigen:
alanyl (membrane) aminopeptidase

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a full-length human ANPEP protein.

Gene:
ANPEP

Gene Alias:
APN/CD13/LAP1/PEPN/gp150/p150

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
290

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_001150.1

Gene Symbols:
ANPEP

Immunogen:
ANPEP (NP_001141.1, 1 a.a. ∼ 967 a.a) full-length human protein.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Img

Abnova Corporation

89-018-881

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Antigen:
annexin A1

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a full-length human ANXA1 protein.

Gene:
ANXA1

Gene Alias:
ANX1/LPC1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
301

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

Applications:
Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_000700

Gene Symbols:
ANXA1

Immunogen:
ANXA1 (NP_000691.1, 1 a.a. ∼ 346 a.a) full-length human protein.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody