89-104-642

HLA-DRB4, Mouse, Clone: 4C8, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-104-642-Each-of-1 In Stock ₹ 41,239.92

89-104-642 - Each of 1

₹ 41,239.92

In Stock

Quantity

1

Base Price: ₹ 41,239.92

GST (18%): ₹ 7,423.186

Total Price: ₹ 48,663.106

Antigen

HLA-DRB4

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

ascites with no preservative

Gene Accession No.

BC005312

Gene Symbols

HLA-DRB4

Immunogen

HLA-DRB4 (AAH05312,30 a.a. ∽ 266 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Regulatory Status

RUO

Gene ID (Entrez)

3126

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Form

Ascites

Applications

ELISA, Western Blot

Clone

4C8

Description

Mouse monoclonal antibody raised against a full-length recombinant HLA-DRB4.

Gene

HLA-DRB4

Gene Alias

DRB4/HLA-DR4B

Host Species

Mouse

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b κ

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Description

  • HLA-DRB4 belongs to the HLA class II beta chain paralogues
  • This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane
  • It plays a central role in the immune system by presenting peptides derived from extracellular proteins
  • Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages)
  • The beta chain is approximately 26-28kDa and its gene contains 6 exons
  • Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail
  • Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities
  • Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
  • DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5
  • The presence of DRB4 is linked with allelic variants of DRB1, otherwise it is omitted
  • There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9
  • [provided by RefSeq Sequence: GDTQPRFLEQAKCECRFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSGLQPTGLLS

Compare Similar Items

Show Difference

Img

Abnova Corporation

89-104-642

--


Antigen:
HLA-DRB4

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
ascites with no preservative

Gene Accession No.:
BC005312

Gene Symbols:
HLA-DRB4

Immunogen:
HLA-DRB4 (AAH05312,30 a.a. ∽ 266 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Regulatory Status:
RUO

Gene ID (Entrez):
3126

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Form:
Ascites

Applications:
ELISA, Western Blot

Clone:
4C8

Description:
Mouse monoclonal antibody raised against a full-length recombinant HLA-DRB4.

Gene:
HLA-DRB4

Gene Alias:
DRB4/HLA-DR4B

Host Species:
Mouse

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ

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Abnova Corporation

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Antigen:
MR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_001531

Gene Symbols:
MR1

Immunogen:
MR1 (NP_001522, 201 a.a. ∽ 300 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Gene ID (Entrez):
3140

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Form:
Antisera

Applications:
ELISA, Western Blot

Clone:
__

Description:
Mouse polyclonal antibody raised against a partial recombinant MR1.

Gene:
MR1

Gene Alias:
HLALS

Host Species:
Mouse

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
__

Isotype:
__

Img

Abnova Corporation

89-104-644

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Antigen:
HLCS

Classification:
Polyclonal

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_000411

Gene Symbols:
HLCS

Immunogen:
HLCS (NP_000402, 627 a.a. ∽ 724 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Gene ID (Entrez):
3141

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Form:
Antisera

Applications:
ELISA, Western Blot

Clone:
__

Description:
Mouse polyclonal antibody raised against a partial recombinant HLCS.

Gene:
HLCS

Gene Alias:
HCS

Host Species:
Mouse

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
__

Isotype:
__

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Antigen:
HMGB2

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
ascites with no preservative

Gene Accession No.:
BC000903

Gene Symbols:
HMGB2

Immunogen:
HMGB2 (AAH00903.2,1 a.a. ∽ 195 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Regulatory Status:
RUO

Gene ID (Entrez):
3148

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Form:
Ascites

Applications:
ELISA, Western Blot

Clone:
3F2

Description:
Mouse monoclonal antibody raised against a full-length recombinant HMGB2.

Gene:
HMGB2

Gene Alias:
HMG2

Host Species:
Mouse

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG κ