89-104-932

MLL, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-104-932-Each-of-1 In Stock ₹ 29,603.76

89-104-932 - Each of 1

₹ 29,603.76

In Stock

Quantity

1

Base Price: ₹ 29,603.76

GST (18%): ₹ 5,328.677

Total Price: ₹ 34,932.437

Antigen

MLL

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a partial recombinant MLL.

Gene

MLL

Gene Alias

ALL-1/CXXC7/FLJ11783/HRX/HTRX1/KMT2A/MLL/GAS7/MLL1A/TET1-MLL/TRX1

Host Species

Mouse

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Form

Antisera

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Formulation

50% glycerol

Gene Accession No.

NM_005933

Gene Symbols

MLL

Immunogen

MLL (NP_005924, 3561 a.a. ∽ 3670 a.a) partial recombinant protein with GST tag.

Regulatory Status

RUO

Gene ID (Entrez)

4297

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Description

  • The MLL gene encodes a DNA-binding protein that methylates histone H3 (see MIM 601128) lys4 (H3K4) and positively regulates expression of target genes, including multiple HOX genes (see MIM 142980)
  • MLL is a frequent target for recurrent translocations in acute leukemias that may be characterized as acute myeloid leukemia (AML; MIM 601626), acute lymphoblastic leukemia (ALL), or mixed lineage (biphenotypic) leukemia (MLL)
  • Leukemias with translocations involving MLL possess unique clinical and biologic characteristics and are often associated with poor prognosis
  • MLL rearrangements are found in more than 70% of infant leukemias, whether the immunophenotype is more consistent with ALL or AML6, but are less frequent in leukemias from older children
  • MLL translocations are also found in approximately 10% of AMLs in adults, as well as in therapy-related leukemias, most often characterized as AML, that develop in patients previously treated with topoisomerase II inhibitors for other malignancies
  • More than 50 different MLL fusion partners have been identified
  • Leukemogenic MLL translocations encode MLL fusion proteins that have lost H3K4 methyltransferase activity
  • A key feature of MLL fusion proteins is their ability to efficiently transform hematopoietic cells into leukemia stem cells (Krivtsov and Armstrong, 2007 [PubMed 17957188]).[supplied by OMIM Sequence: RTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLV

Compare Similar Items

Show Difference

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Abnova Corporation

89-104-932

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Antigen:
MLL

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant MLL.

Gene:
MLL

Gene Alias:
ALL-1/CXXC7/FLJ11783/HRX/HTRX1/KMT2A/MLL/GAS7/MLL1A/TET1-MLL/TRX1

Host Species:
Mouse

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Antisera

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_005933

Gene Symbols:
MLL

Immunogen:
MLL (NP_005924, 3561 a.a. ∽ 3670 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Gene ID (Entrez):
4297

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Abnova Corporation

89-104-934

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Antigen:
MMP13

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant MMP13.

Gene:
MMP13

Gene Alias:
CLG3

Host Species:
Mouse

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Antisera

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_002427

Gene Symbols:
MMP13

Immunogen:
MMP13 (NP_002418, 362 a.a. ∽ 471 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Gene ID (Entrez):
4322

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Antigen:
CD200

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant CD200.

Gene:
CD200

Gene Alias:
MOX1/MOX2/MRC/OX-2

Host Species:
Mouse

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Antisera

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_005944

Gene Symbols:
CD200

Immunogen:
CD200 (NP_005935, 34 a.a. to 124 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Gene ID (Entrez):
4345

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Antigen:
MPP1

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a full-length recombinant MPP1.

Gene:
MPP1

Gene Alias:
AAG12/DXS552/DXS552E/EMP55/MRG1/PEMP

Host Species:
Mouse

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Antisera

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
BC002392

Gene Symbols:
MPP1

Immunogen:
MPP1 (AAH02392, 1 a.a. ∽ 466 a.a) full-length recombinant protein with GST tag.

Regulatory Status:
RUO

Gene ID (Entrez):
4354

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.