89-106-484
CHEK2, Mouse, Clone: 6B8, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-106-484-Each-of-1 | In Stock | ₹ 41,239.92 |
89-106-484 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,239.92
GST (18%): ₹ 7,423.186
Total Price: ₹ 48,663.106
Antigen
CHEK2
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
ascites with no preservative
Gene Accession No.
BC004207
Gene Symbols
CHEK2
Immunogen
CHEK2 (AAH04207,1 a.a. ∽ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Regulatory Status
RUO
Gene ID (Entrez)
11200
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form
Ascites
Applications
ELISA, Western Blot
Clone
6B8
Description
Mouse monoclonal antibody raised against a partial recombinant CHEK2.
Gene
CHEK2
Gene Alias
CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species
Mouse
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators
- The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor
- It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage
- When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1
- In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage
- Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53
- Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors
- This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases
- Three transcript variants encoding different isoforms have been found for this gene
- [provided by RefSeq Sequence: MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQ
Compare Similar Items
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Antigen: CHEK2
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: ascites with no preservative
Gene Accession No.: BC004207
Gene Symbols: CHEK2
Immunogen: CHEK2 (AAH04207,1 a.a. ∽ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Regulatory Status: RUO
Gene ID (Entrez): 11200
Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form: Ascites
Applications: ELISA, Western Blot
Clone: 6B8
Description: Mouse monoclonal antibody raised against a partial recombinant CHEK2.
Gene: CHEK2
Gene Alias: CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species: Mouse
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CHEK2
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
ascites with no preservative
Gene Accession No.:
BC004207
Gene Symbols:
CHEK2
Immunogen:
CHEK2 (AAH04207,1 a.a. ∽ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Regulatory Status:
RUO
Gene ID (Entrez):
11200
Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form:
Ascites
Applications:
ELISA, Western Blot
Clone:
6B8
Description:
Mouse monoclonal antibody raised against a partial recombinant CHEK2.
Gene:
CHEK2
Gene Alias:
CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species:
Mouse
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CHEK2
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: ascites with no preservative
Gene Accession No.: BC004207
Gene Symbols: CHEK2
Immunogen: CHEK2 (AAH04207.1,1 a.a. ∽ 543 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Regulatory Status: RUO
Gene ID (Entrez): 11200
Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form: Ascites
Applications: ELISA, Western Blot
Clone: 3E10
Description: Mouse monoclonal antibody raised against a full-length recombinant CHEK2.
Gene: CHEK2
Gene Alias: CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species: Mouse
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CHEK2
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
ascites with no preservative
Gene Accession No.:
BC004207
Gene Symbols:
CHEK2
Immunogen:
CHEK2 (AAH04207.1,1 a.a. ∽ 543 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Regulatory Status:
RUO
Gene ID (Entrez):
11200
Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form:
Ascites
Applications:
ELISA, Western Blot
Clone:
3E10
Description:
Mouse monoclonal antibody raised against a full-length recombinant CHEK2.
Gene:
CHEK2
Gene Alias:
CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species:
Mouse
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: POLI
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: ascites with no preservative
Gene Accession No.: BC032662
Gene Symbols: POLI
Immunogen: POLI (AAH32662,616 a.a. ∽ 715 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Regulatory Status: RUO
Gene ID (Entrez): 11201
Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form: Ascites
Applications: ELISA, Western Blot
Clone: 8G9
Description: Mouse monoclonal antibody raised against a partial recombinant POLI.
Gene: POLI
Gene Alias: RAD30B/RAD3OB
Host Species: Mouse
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG3 κ
Antigen:
POLI
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
ascites with no preservative
Gene Accession No.:
BC032662
Gene Symbols:
POLI
Immunogen:
POLI (AAH32662,616 a.a. ∽ 715 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Regulatory Status:
RUO
Gene ID (Entrez):
11201
Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form:
Ascites
Applications:
ELISA, Western Blot
Clone:
8G9
Description:
Mouse monoclonal antibody raised against a partial recombinant POLI.
Gene:
POLI
Gene Alias:
RAD30B/RAD3OB
Host Species:
Mouse
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG3 κ
Antigen: AKAP11
Classification: Polyclonal
Conjugate: Unconjugated
Formulation: 50% glycerol
Gene Accession No.: NM_016248
Gene Symbols: AKAP11
Immunogen: AKAP11 (NP_057332, 1801 a.a. to 1901 a.a) partial recombinant protein with GST tag.
Regulatory Status: RUO
Gene ID (Entrez): 11215
Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form: Antisera
Applications: ELISA, Western Blot
Clone: __
Description: Mouse polyclonal antibody raised against a partial recombinant AKAP11.
Gene: AKAP11
Gene Alias: AKAP220/DKFZp781I12161/FLJ11304/KIAA0629/PRKA11
Host Species: Mouse
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: __
Isotype: __
Antigen:
AKAP11
Classification:
Polyclonal
Conjugate:
Unconjugated
Formulation:
50% glycerol
Gene Accession No.:
NM_016248
Gene Symbols:
AKAP11
Immunogen:
AKAP11 (NP_057332, 1801 a.a. to 1901 a.a) partial recombinant protein with GST tag.
Regulatory Status:
RUO
Gene ID (Entrez):
11215
Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form:
Antisera
Applications:
ELISA, Western Blot
Clone:
__
Description:
Mouse polyclonal antibody raised against a partial recombinant AKAP11.
Gene:
AKAP11
Gene Alias:
AKAP220/DKFZp781I12161/FLJ11304/KIAA0629/PRKA11
Host Species:
Mouse
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
__
Isotype:
__