89-107-813

MBS/MYPT1, Mouse, Clone: AF-20, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-107-813-Each-of-1 In Stock ₹ 69,260.82

89-107-813 - Each of 1

₹ 69,260.82

In Stock

Quantity

1

Base Price: ₹ 69,260.82

GST (18%): ₹ 12,466.948

Total Price: ₹ 81,727.768

Antigen

MBS/MYPT1

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

Western Blot (1-2 ug/mL) ELISA (1 ug/mL) The optimal working dilution should be determined by the end user.

Gene

PPP1R12A

Gene Alias

MBS/MGC133042/MYPT1

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Chicken, Human, Mouse, Rat

Form

Liquid

Applications

ELISA, Immunofluorescence, Western Blot

Clone

AF-20

Description

Mouse monoclonal antibody raised against synthetic phosphopeptide of MBS/MYPT1.

Formulation

In 10mM HEPES/KOH, 150mM NaCl, pH 7.5 (50% glycerol)

Gene Accession No.

D87930

Gene Symbols

PPP1R12A

Immunogen

Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T696 of human MBS/MYPT1.

Regulatory Status

RUO

Gene ID (Entrez)

4659

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1

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Description

  • Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase
  • Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho
  • The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells
  • The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC
  • Rho-associated kinase (Rho-kinase), which is activated by GTP
  • RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase
  • Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC
  • Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase
  • Several transcript variants encoding different isoforms have been found for this gene
  • [provided by RefSeq

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Img

Abnova Corporation

89-107-813

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Antigen:
MBS/MYPT1

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1-2 ug/mL) ELISA (1 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
PPP1R12A

Gene Alias:
MBS/MGC133042/MYPT1

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Chicken, Human, Mouse, Rat

Form:
Liquid

Applications:
ELISA, Immunofluorescence, Western Blot

Clone:
AF-20

Description:
Mouse monoclonal antibody raised against synthetic phosphopeptide of MBS/MYPT1.

Formulation:
In 10mM HEPES/KOH, 150mM NaCl, pH 7.5 (50% glycerol)

Gene Accession No.:
D87930

Gene Symbols:
PPP1R12A

Immunogen:
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T696 of human MBS/MYPT1.

Regulatory Status:
RUO

Gene ID (Entrez):
4659

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

Img

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89-107-814

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Antigen:
Rb

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1-2 ug/mL) Immunoprecipitation (2-4 ug/mL) ELISA (5-10 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
RB1

Gene Alias:
OSRC/RB/p105-Rb/pRb/pp110

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunoprecipitation, Western Blot

Clone:
3C11

Description:
Mouse monoclonal antibody raised against synthetic phosphopeptide of Rb.

Formulation:
In 10mM phosphate buffer, 150mM NaCl, pH 7.5 (50% glycerol)

Gene Accession No.:
NM_000321

Gene Symbols:
RB1

Immunogen:
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S612 of human Rb.

Regulatory Status:
RUO

Gene ID (Entrez):
5925

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG2a

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Antigen:
HbA1c

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
__

Gene:
HBA1

Gene Alias:
HBH/HBA-T3

Host Species:
Mouse

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Ascites

Applications:
ELISA

Clone:
1D3

Description:
Mouse monoclonal antibody raised against glycosylated hemoglobin.

Formulation:
In ascites fluid

Gene Accession No.:
NM_000558

Gene Symbols:
HBA1

Immunogen:
A peptide (conjugated with KLH) corresponding to N-terminus glycosylated HbA1c.

Regulatory Status:
RUO

Gene ID (Entrez):
3039

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG2a κ

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Antigen:
CHUK

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
The optimal working dilution should be determined by the end user.

Gene:
CHUK

Gene Alias:
IKBKA/IKK-alpha/IKK1/IKKA/NFKBIKA/TCF16

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Monkey, Mouse

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Clone:
14A231

Description:
Mouse monoclonal antibody raised against full length recombinant CHUK.

Formulation:
In PBS (0.05% BSA, 0.05% sodium azide)

Gene Accession No.:
__

Gene Symbols:
CHUK

Immunogen:
Recombinant His fusion protein corresponding to full length human CHUK.

Regulatory Status:
RUO

Gene ID (Entrez):
1147

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1