89-108-587

CDKN2A, Mouse, Clone: 2D9A12, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-108-587-Each-of-1 In Stock ₹ 1,00,533.00

89-108-587 - Each of 1

₹ 1,00,533.00

In Stock

Quantity

1

Base Price: ₹ 1,00,533.00

GST (18%): ₹ 18,095.94

Total Price: ₹ 1,18,628.94

Antigen

CDKN2A

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) The optimal working dilution should be determined by the end user.

Gene

CDKN2A

Gene Symbols

CDKN2A

Immunogen

Recombinant protein corresponding to human CDKN2A.

Regulatory Status

RUO

Gene ID (Entrez)

1029

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG2b

Applications

ELISA, Immunohistochemistry, Western Blot

Clone

2D9A12

Description

Mouse monoclonal antibody raised against recombinant CDKN2A.

Formulation

In ascites (0.03% sodium azide)

Gene Alias

ARF/CDK4I/CDKN2/CMM2/INK4/INK4a/MLM/MTS1/TP16/p14/p14ARF/p16/p16INK4/p16INK4a/p19

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • This gene generates several transcript variants which differ in their first exons
  • At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase
  • The remaining transcript includes an alternate first exon located 20kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants
  • This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, MDM1, a protein responsible for the degradation of p53
  • In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control
  • This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene
  • [provided by RefSeq

Compare Similar Items

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Img

Abnova Corporation

89-108-587

--


Antigen:
CDKN2A

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) The optimal working dilution should be determined by the end user.

Gene:
CDKN2A

Gene Symbols:
CDKN2A

Immunogen:
Recombinant protein corresponding to human CDKN2A.

Regulatory Status:
RUO

Gene ID (Entrez):
1029

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG2b

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
2D9A12

Description:
Mouse monoclonal antibody raised against recombinant CDKN2A.

Formulation:
In ascites (0.03% sodium azide)

Gene Alias:
ARF/CDK4I/CDKN2/CMM2/INK4/INK4a/MLM/MTS1/TP16/p14/p14ARF/p16/p16INK4/p16INK4a/p19

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Abnova Corporation

89-108-588

--


Antigen:
CDKN2A

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) The optimal working dilution should be determined by the end user.

Gene:
CDKN2A

Gene Symbols:
CDKN2A

Immunogen:
Recombinant protein corresponding to human CDKN2A.

Regulatory Status:
RUO

Gene ID (Entrez):
1029

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
1E12E10

Description:
Mouse monoclonal antibody raised against recombinant CDKN2A.

Formulation:
In ascites (0.03% sodium azide)

Gene Alias:
ARF/CDK4I/CDKN2/CMM2/INK4/INK4a/MLM/MTS1/TP16/p14/p14ARF/p16/p16INK4/p16INK4a/p19

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Img

Abnova Corporation

89-108-590

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Antigen:
MAPKAPK5

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) The optimal working dilution should be determined by the end user.

Gene:
MAPKAPK5

Gene Symbols:
MAPKAPK5

Immunogen:
Recombinant protein corresponding to human MAPKAPK5.

Regulatory Status:
RUO

Gene ID (Entrez):
8550

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
7H10B4

Description:
Mouse monoclonal antibody raised against recombinant MAPKAPK5.

Formulation:
In ascites (0.03% sodium azide)

Gene Alias:
PRAK

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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Abnova Corporation

89-108-591

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Antigen:
PTEN

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
ELISA (1:10000) Western Blot (1:500-1:2000) Immunofluorescence (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.

Gene:
PTEN

Gene Symbols:
PTEN

Immunogen:
Recombinant protein corresponding to human PTEN.

Regulatory Status:
RUO

Gene ID (Entrez):
5728

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Immunofluorescence, Western Blot

Clone:
1B8

Description:
Mouse monoclonal antibody raised against recombinant PTEN.

Formulation:
In PBS (50% glycerol, 0.03% sodium azide)

Gene Alias:
10q23del/BZS/MGC11227/MHAM/MMAC1/PTEN1/TEP1

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid