89-108-753

MLL, Mouse, Clone: 10F8D7, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-108-753-Each-of-1 In Stock ₹ 83,934.36

89-108-753 - Each of 1

₹ 83,934.36

In Stock

Quantity

1

Base Price: ₹ 83,934.36

GST (18%): ₹ 15,108.185

Total Price: ₹ 99,042.545

Antigen

MLL

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) The optimal working dilution should be determined by the end user.

Gene

MLL

Gene Symbols

MLL

Immunogen

Recombinant protein corresponding to amino acids 3751-3968 of human MLL.

Regulatory Status

RUO

Gene ID (Entrez)

4297

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1

Applications

ELISA, Immunohistochemistry, Western Blot

Clone

10F8D7

Description

Mouse monoclonal antibody raised against partial recombinant MLL.

Formulation

In ascites (0.03% sodium azide)

Gene Alias

ALL-1/CXXC7/FLJ11783/HRX/HTRX1/KMT2A/MLL/GAS7/MLL1A/TET1-MLL/TRX1

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • The MLL gene encodes a DNA-binding protein that methylates histone H3 (see MIM 601128) lys4 (H3K4) and positively regulates expression of target genes, including multiple HOX genes (see MIM 142980)
  • MLL is a frequent target for recurrent translocations in acute leukemias that may be characterized as acute myeloid leukemia (AML; MIM 601626), acute lymphoblastic leukemia (ALL), or mixed lineage (biphenotypic) leukemia (MLL)
  • Leukemias with translocations involving MLL possess unique clinical and biologic characteristics and are often associated with poor prognosis
  • MLL rearrangements are found in more than 70% of infant leukemias, whether the immunophenotype is more consistent with ALL or AML6, but are less frequent in leukemias from older children
  • MLL translocations are also found in approximately 10% of AMLs in adults, as well as in therapy-related leukemias, most often characterized as AML, that develop in patients previously treated with topoisomerase II inhibitors for other malignancies
  • More than 50 different MLL fusion partners have been identified
  • Leukemogenic MLL translocations encode MLL fusion proteins that have lost H3K4 methyltransferase activity
  • A key feature of MLL fusion proteins is their ability to efficiently transform hematopoietic cells into leukemia stem cells (Krivtsov and Armstrong, 2007 [PubMed 17957188]).[supplied by OMIM

Compare Similar Items

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Abnova Corporation

89-108-753

--


Antigen:
MLL

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) The optimal working dilution should be determined by the end user.

Gene:
MLL

Gene Symbols:
MLL

Immunogen:
Recombinant protein corresponding to amino acids 3751-3968 of human MLL.

Regulatory Status:
RUO

Gene ID (Entrez):
4297

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
10F8D7

Description:
Mouse monoclonal antibody raised against partial recombinant MLL.

Formulation:
In ascites (0.03% sodium azide)

Gene Alias:
ALL-1/CXXC7/FLJ11783/HRX/HTRX1/KMT2A/MLL/GAS7/MLL1A/TET1-MLL/TRX1

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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Abnova Corporation

89-108-754

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Antigen:
LPA

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) The optimal working dilution should be determined by the end user.

Gene:
LPA

Gene Symbols:
LPA

Immunogen:
Recombinant protein corresponding to amino acids 4330-4521 of human LPA.

Regulatory Status:
RUO

Gene ID (Entrez):
4018

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
8F6A9, 8H5C5

Description:
Mouse monoclonal antibody raised against partial recombinant LPA.

Formulation:
In ascites (0.03% sodium azide)

Gene Alias:
AK38/APOA/LP

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Abnova Corporation

89-108-756

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Antigen:
KRT19

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) The optimal working dilution should be determined by the end user.

Gene:
KRT19

Gene Symbols:
KRT19

Immunogen:
Recombinant protein corresponding to amino acids 80-400 of human KRT19.

Regulatory Status:
RUO

Gene ID (Entrez):
3880

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
9H8G6

Description:
Mouse monoclonal antibody raised against partial recombinant KRT19.

Formulation:
In ascites (0.03% sodium azide)

Gene Alias:
CK19/K19/K1CS/MGC15366

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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Abnova Corporation

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Antigen:
LIN28

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) The optimal working dilution should be determined by the end user.

Gene:
LIN28

Gene Symbols:
LIN28

Immunogen:
Recombinant protein corresponding to amino acids 93-209 of human LIN28.

Regulatory Status:
RUO

Gene ID (Entrez):
79727

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot

Clone:
6D1F9

Description:
Mouse monoclonal antibody raised against partial recombinant LIN28.

Formulation:
In 10mM PBS, pH 7.4 (0.03% sodium azide)

Gene Alias:
CSDD1/FLJ12457/LIN-28/LIN28A/ZCCHC1

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid