89-109-423
TP53, Mouse, Clone: BP53-12, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-109-423-Each-of-1 | In Stock | ₹ 65,710.08 |
89-109-423 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 65,710.08
GST (18%): ₹ 11,827.814
Total Price: ₹ 77,537.894
Antigen
TP53
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:200) Western Blot (1-3 ug/ml) The optimal working dilution should be determined by the end user.
Gene
TP53
Gene Symbols
TP53
Immunogen
Recombinant protein corresponding to full length human TP53.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone
BP53-12
Description
Mouse monoclonal antibody raised against full length recombinant TP53.
Formulation
In PBS (0.05% BSA, 0.05% sodium azide)
Gene Alias
FLJ92943/LFS1/TRP53/p53
Host Species
Mouse
Purification Method
Protein G purification
Regulatory Status
RUO
Gene ID (Entrez)
7157
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG2a κ
Description
- This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism
- p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy
- p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains
- It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor
- Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity
- Alterations of this gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome
- Multiple p53 variants due to alternative promoters and multiple alternative splicing have been found
- These variants encode distinct isoforms, which can regulate p53 transcriptional activity
- [provided by RefSeq]
Compare Similar Items
Show Difference
Antigen: TP53
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:200) Western Blot (1-3 ug/ml) The optimal working dilution should be determined by the end user.
Gene: TP53
Gene Symbols: TP53
Immunogen: Recombinant protein corresponding to full length human TP53.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone: BP53-12
Description: Mouse monoclonal antibody raised against full length recombinant TP53.
Formulation: In PBS (0.05% BSA, 0.05% sodium azide)
Gene Alias: FLJ92943/LFS1/TRP53/p53
Host Species: Mouse
Purification Method: Protein G purification
Regulatory Status: RUO
Gene ID (Entrez): 7157
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG2a κ
Antigen:
TP53
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:200) Western Blot (1-3 ug/ml) The optimal working dilution should be determined by the end user.
Gene:
TP53
Gene Symbols:
TP53
Immunogen:
Recombinant protein corresponding to full length human TP53.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone:
BP53-12
Description:
Mouse monoclonal antibody raised against full length recombinant TP53.
Formulation:
In PBS (0.05% BSA, 0.05% sodium azide)
Gene Alias:
FLJ92943/LFS1/TRP53/p53
Host Species:
Mouse
Purification Method:
Protein G purification
Regulatory Status:
RUO
Gene ID (Entrez):
7157
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG2a κ
Antigen: PECAM1
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:200) Western Blot (1-3 ug/ml) The optimal working dilution should be determined by the end user.
Gene: PECAM1
Gene Symbols: PECAM1
Immunogen: Spleen membranes from a human with hairy cell leukemia.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Clone: C31.7
Description: Mouse monoclonal antibody raised against PECAM1.
Formulation: In PBS (0.05% BSA, 0.05% sodium azide)
Gene Alias: CD31/PECAM-1
Host Species: Mouse
Purification Method: Protein G purification
Regulatory Status: RUO
Gene ID (Entrez): 5175
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG1 κ
Antigen:
PECAM1
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:200) Western Blot (1-3 ug/ml) The optimal working dilution should be determined by the end user.
Gene:
PECAM1
Gene Symbols:
PECAM1
Immunogen:
Spleen membranes from a human with hairy cell leukemia.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Clone:
C31.7
Description:
Mouse monoclonal antibody raised against PECAM1.
Formulation:
In PBS (0.05% BSA, 0.05% sodium azide)
Gene Alias:
CD31/PECAM-1
Host Species:
Mouse
Purification Method:
Protein G purification
Regulatory Status:
RUO
Gene ID (Entrez):
5175
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG1 κ
Antigen: IGKC
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:400-1:800) The optimal working dilution should be determined by the end user.
Gene: IGKC
Gene Symbols: IGKC
Immunogen: B lymphoma cells.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (PFA fixed)
Clone: L1C1
Description: Mouse monoclonal antibody raised against IGKC.
Formulation: In PBS (0.05% BSA, 0.05% sodium azide)
Gene Alias: HCAK1/Km/MGC111575/MGC62011/MGC72072/MGC88770/MGC88771/MGC88809
Host Species: Mouse
Purification Method: Protein G purification
Regulatory Status: RUO
Gene ID (Entrez): 3514
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG1 κ
Antigen:
IGKC
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:400-1:800) The optimal working dilution should be determined by the end user.
Gene:
IGKC
Gene Symbols:
IGKC
Immunogen:
B lymphoma cells.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (PFA fixed)
Clone:
L1C1
Description:
Mouse monoclonal antibody raised against IGKC.
Formulation:
In PBS (0.05% BSA, 0.05% sodium azide)
Gene Alias:
HCAK1/Km/MGC111575/MGC62011/MGC72072/MGC88770/MGC88771/MGC88809
Host Species:
Mouse
Purification Method:
Protein G purification
Regulatory Status:
RUO
Gene ID (Entrez):
3514
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG1 κ
Antigen: MLANA
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500) The optimal working dilution should be determined by the end user.
Gene: MLANA
Gene Symbols: MLANA
Immunogen: Recombinant protein corresponding to human MLANA.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone: M2-9E3
Description: Mouse monoclonal antibody raised against MLANA
Formulation: In PBS (0.05% BSA, 0.05% sodium azide)
Gene Alias: MART-1/MART1
Host Species: Mouse
Purification Method: Protein G purification
Regulatory Status: RUO
Gene ID (Entrez): 2315
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG2b κ
Antigen:
MLANA
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500) The optimal working dilution should be determined by the end user.
Gene:
MLANA
Gene Symbols:
MLANA
Immunogen:
Recombinant protein corresponding to human MLANA.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone:
M2-9E3
Description:
Mouse monoclonal antibody raised against MLANA
Formulation:
In PBS (0.05% BSA, 0.05% sodium azide)
Gene Alias:
MART-1/MART1
Host Species:
Mouse
Purification Method:
Protein G purification
Regulatory Status:
RUO
Gene ID (Entrez):
2315
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG2b κ