89-110-449

CDKN2A, Mouse, Clone: IMD-16, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-110-449-Each-of-1 In Stock ₹ 66,137.88

89-110-449 - Each of 1

₹ 66,137.88

In Stock

Quantity

1

Base Price: ₹ 66,137.88

GST (18%): ₹ 11,904.818

Total Price: ₹ 78,042.698

Antigen

CDKN2A

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

Western Blot (0.5-1 ug/mL) Immunohistochemistry (Frozen sections) (1-2 ug/mL) The optimal working dilution should be determined by the end user.

Gene

CDKN2A

Gene Symbols

CDKN2A

Immunogen

Recombinant protein corresponding to full length human CDKN2A.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Lyophilized

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Clone

DCS-50

Description

Mouse monoclonal antibody raised against full length recombinant CDKN2A.

Formulation

Lyophilized from 1.2% sodium acetate (2mg BSA, 0.01mg sodium azide)

Gene Alias

ARF/CDK4I/CDKN2/CMM2/INK4/INK4a/MLM/MTS1/TP16/p14/p14ARF/p16/p16INK4/p16INK4a/p19

Host Species

Mouse

Purification Method

Affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

1029

Content And Storage

Store at -20°C on dry atmosphere. After reconstitution with 1mL of 1.2% sodium acetate or neutral PBS to a concentration of 100μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1

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Description

  • This gene generates several transcript variants which differ in their first exons
  • At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase
  • The remaining transcript includes an alternate first exon located 20kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants
  • This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, MDM1, a protein responsible for the degradation of p53
  • In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control
  • This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene
  • [provided by RefSeq

Compare Similar Items

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Img

Abnova Corporation

89-110-449

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Antigen:
CDKN2A

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (0.5-1 ug/mL) Immunohistochemistry (Frozen sections) (1-2 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
CDKN2A

Gene Symbols:
CDKN2A

Immunogen:
Recombinant protein corresponding to full length human CDKN2A.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Clone:
DCS-50

Description:
Mouse monoclonal antibody raised against full length recombinant CDKN2A.

Formulation:
Lyophilized from 1.2% sodium acetate (2mg BSA, 0.01mg sodium azide)

Gene Alias:
ARF/CDK4I/CDKN2/CMM2/INK4/INK4a/MLM/MTS1/TP16/p14/p14ARF/p16/p16INK4/p16INK4a/p19

Host Species:
Mouse

Purification Method:
Affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
1029

Content And Storage:
Store at -20°C on dry atmosphere. After reconstitution with 1mL of 1.2% sodium acetate or neutral PBS to a concentration of 100μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

Img

Abnova Corporation

89-110-450

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Antigen:
PXN

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
PXN

Gene Symbols:
PXN

Immunogen:
Recombinant protein corresponding to amino acids 305-559 of chicken PXN.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Chicken, Human, Mouse, Rat

Form:
Lyophilized

Applications:
Immunocytochemistry, Western Blot

Clone:
PXC-10

Description:
Mouse monoclonal antibody raised against partial recombinant PXN.

Formulation:
Lyophilized from 1.2% sodium acetate (2mg BSA, 0.01mg sodium azide)

Gene Alias:
__

Host Species:
Mouse

Purification Method:
Affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
395832

Content And Storage:
Store at -20°C on dry atmosphere. After reconstitution with 1mL of 1.2% sodium acetate or neutral PBS to a concentration of 100μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

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Abnova Corporation

89-110-452

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Antigen:
SMAD4

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (2-4 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
SMAD4

Gene Symbols:
SMAD4

Immunogen:
Recombinant protein corresponding to full length human SMAD4.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Applications:
Immunocytochemistry, Western Blot

Clone:
DCS-46

Description:
Mouse monoclonal antibody raised against full length recombinant SMAD4.

Formulation:
Lyophilized from 1.2% sodium acetate (2mg BSA, 0.01mg sodium azide)

Gene Alias:
DPC4/JIP/MADH4

Host Species:
Mouse

Purification Method:
Affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
4089

Content And Storage:
Store at -20°C on dry atmosphere. After reconstitution with 1mL of 1.2% sodium acetate or neutral PBS to a concentration of 100μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

Img

Abnova Corporation

89-110-455

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Antigen:
VCL

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1-2 ug/mL) Immunohistochemistry (Frozen section) (2-4 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
VCL

Gene Symbols:
VCL

Immunogen:
Native purified human uterus VCL.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Applications:
Immunohistochemistry (Frozen), Western Blot

Clone:
hVIN-1

Description:
Mouse monoclonal antibody raised against native VCL.

Formulation:
Lyophilized from 1.2% sodium acetate (2mg BSA, 0.01mg sodium azide)

Gene Alias:
CMD1W/MVCL

Host Species:
Mouse

Purification Method:
Affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
7414

Content And Storage:
Store at -20°C on dry atmosphere. After reconstitution with 1mL of 1.2% sodium acetate or neutral PBS to a concentration of 100μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1