89-111-399

APAF1, Rat, Clone: 2E12, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-111-399-Each-of-1 In Stock ₹ 1,65,387.48

89-111-399 - Each of 1

₹ 1,65,387.48

In Stock

Quantity

1

Base Price: ₹ 1,65,387.48

GST (18%): ₹ 29,769.746

Total Price: ₹ 1,95,157.226

Antigen

APAF1

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

The optimal working dilution should be determined by the end user.

Gene

APAF1

Gene Symbols

APAF1

Immunogen

Recombinant Flag fusion protein corresponding to amino acids 1-464 of human APAF1.

Regulatory Status

RUO

Gene ID (Entrez)

317

Target Species

Human

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone

2E12

Description

Rat monoclonal antibody raised against partial recombinant APAF1.

Formulation

In PBS (0.02% sodium azide)

Gene Alias

CED4/DKFZp781B1145

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

Recognizes the CARD domain of human Apaf-1. Does not cross-react with mouse or rat Apaf-1.

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG2a

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Description

  • This gene encodes a cytoplasmic protein that initiates apoptosis
  • This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC)
  • Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome
  • The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form
  • Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis
  • Alternative splicing results in several transcript variants encoding different isoforms
  • [provided by RefSeq

Compare Similar Items

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Img

Abnova Corporation

89-111-399

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Antigen:
APAF1

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
The optimal working dilution should be determined by the end user.

Gene:
APAF1

Gene Symbols:
APAF1

Immunogen:
Recombinant Flag fusion protein corresponding to amino acids 1-464 of human APAF1.

Regulatory Status:
RUO

Gene ID (Entrez):
317

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
2E12

Description:
Rat monoclonal antibody raised against partial recombinant APAF1.

Formulation:
In PBS (0.02% sodium azide)

Gene Alias:
CED4/DKFZp781B1145

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Recognizes the CARD domain of human Apaf-1. Does not cross-react with mouse or rat Apaf-1.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG2a

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89-111-406

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Antigen:
ABCB11

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1:50-1:200) The optimal working dilution should be determined by the end user.

Gene:
ABCB11

Gene Symbols:
ABCB11

Immunogen:
A synthetic peptide corresponding to amino acids 705-718 of human ABCB11.

Regulatory Status:
RUO

Gene ID (Entrez):
8647

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
USal-hBSEP-McAb-1

Description:
Mouse monoclonal antibody raised against synthetic peptide of ABCB11.

Formulation:
In buffer containing 100nM sodium azide

Gene Alias:
ABC16/BSEP/PFIC-2/PFIC2/PGY4/SPGP

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Recognizes human SPGP. Does not cross-react with human P-glycoprotein.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

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Abnova Corporation

89-111-411

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Antigen:
Casp1

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
The optimal working dilution should be determined by the end user.

Gene:
Casp1

Gene Symbols:
Casp1

Immunogen:
A synthetic peptide corresponding to amino acids 206-220 of mouse Casp1.

Regulatory Status:
RUO

Gene ID (Entrez):
12362

Target Species:
Mouse

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
1H11

Description:
Rat monoclonal antibody raised against synthetic peptide of Casp1.

Formulation:
In PBS (0.02% sodium azide)

Gene Alias:
ICE/Il1bc

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Recognizes an epitope within the p20 fragment of mouse caspase-1. Detects a band of ∼45 KDa by Western blot. Does not cross-react with mouse caspase-11 or -12.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

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Antigen:
Casp8

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
The optimal working dilution should be determined by the end user.

Gene:
Casp8

Gene Symbols:
Casp8

Immunogen:
Recombinant protein corresponding to p18 subunit of mouse Casp8.

Regulatory Status:
RUO

Gene ID (Entrez):
12370

Target Species:
Mouse

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
1G12

Description:
Rat monoclonal antibody raised against recombinant Casp8.

Formulation:
In PBS (0.02% sodium azide)

Gene Alias:
Caspase-8/FLICE/MACH/Mch5

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Recognizes the p18 subunit of mouse caspase-8. Detects bands of ∼55 KDa (full length caspase-8) and ∼18 KDa (apoptosis-induced cleavage fragment) by Western blot. Does not cross-react with human caspase-8.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1