89-111-505

CD59, Mouse, Clone: MEM-43/5, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-111-505-Each-of-1 In Stock ₹ 51,934.92

89-111-505 - Each of 1

₹ 51,934.92

In Stock

Quantity

1

Base Price: ₹ 51,934.92

GST (18%): ₹ 9,348.286

Total Price: ₹ 61,283.206

Antigen

CD59

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

Flow Cytometry (1 ug/mL) Western Blot (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) The optimal working dilution should be determined by the end user.

Gene

CD59

Gene Symbols

CD59

Immunogen

Native Thymocytes and T lymphocytes.

Regulatory Status

RUO

Gene ID (Entrez)

966

Target Species

Human, Mouse

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Clone

MEM-43/5

Description

Mouse monoclonal antibody raised against native CD59.

Formulation

In PBS, pH 7.4 (0.09% sodium azide)

Gene Alias

16.3A5/1F5/EJ16/EJ30/EL32/FLJ38134/FLJ92039/G344/HRF-20/HRF20/MAC-IP/MACIF/MEM43/MGC2354/MIC11/MIN1/MIN2/MIN3/MIRL/MSK21/p18-20

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody reacts with well defined epitope (around L33) on CD59 (Protectin), a 18-20 KDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed on all hematopoietic cells; it is widely present on cells in all tissues. This antibody does not compete with most other CD59 antibodies.

Content And Storage

Store at 4°C. Do not freeze.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG2b

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Description

  • Description This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction
  • This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation
  • This protein also plays a role in signal transduction pathways in the activation of T cells
  • Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction
  • Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene
  • [provided by RefSeq

Compare Similar Items

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Abnova Corporation

89-111-505

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Antigen:
CD59

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Flow Cytometry (1 ug/mL) Western Blot (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
CD59

Gene Symbols:
CD59

Immunogen:
Native Thymocytes and T lymphocytes.

Regulatory Status:
RUO

Gene ID (Entrez):
966

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Clone:
MEM-43/5

Description:
Mouse monoclonal antibody raised against native CD59.

Formulation:
In PBS, pH 7.4 (0.09% sodium azide)

Gene Alias:
16.3A5/1F5/EJ16/EJ30/EL32/FLJ38134/FLJ92039/G344/HRF-20/HRF20/MAC-IP/MACIF/MEM43/MGC2354/MIC11/MIN1/MIN2/MIN3/MIRL/MSK21/p18-20

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody reacts with well defined epitope (around L33) on CD59 (Protectin), a 18-20 KDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed on all hematopoietic cells; it is widely present on cells in all tissues. This antibody does not compete with most other CD59 antibodies.

Content And Storage:
Store at 4°C. Do not freeze.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG2b

Img

Abnova Corporation

89-111-506

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Antigen:
HLA-E

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
The optimal working dilution should be determined by the end user.

Gene:
HLA-E

Gene Symbols:
HLA-E

Immunogen:
Recombinant protein corresponding to human HLA-E.

Regulatory Status:
RUO

Gene ID (Entrez):
3133

Target Species:
Human, Primate

Form:
Liquid

Applications:
Flow Cytometry, Immunoprecipitation

Clone:
MEM-E/06

Description:
Mouse monoclonal antibody raised against recombinant HLA-E.

Formulation:
In TBS, pH 8.0 (0.09% sodium azide)

Gene Alias:
DKFZp686P19218/EA1.2/EA2.1/HLA-6.2/MHC/QA1

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results showed that This antibody cross-reacts with some classical MHC ClassI molecules (HLA-A3, -A11, -B7). However, the recent Workshop I Session on the 3rd International Conference on HLA-G (Paris, July 2003) confirmed that This antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32,-B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7.

Content And Storage:
Store at 4°C. Do not freeze.

Isotype:
IgG1

Img

Abnova Corporation

89-111-507

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Antigen:
HLA-E

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Flow Cytometry (10 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Immunoprecipitation (10 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
HLA-E

Gene Symbols:
HLA-E

Immunogen:
Recombinant protein corresponding to human HLA-E.

Regulatory Status:
RUO

Gene ID (Entrez):
3133

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunoprecipitation

Clone:
MEM-E/07

Description:
Mouse monoclonal antibody raised against recombinant HLA-E.

Formulation:
In PBS, pH 7.4 (0.09% sodium azide)

Gene Alias:
DKFZp686P19218/EA1.2/EA2.1/HLA-6.2/MHC/QA1

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results revealed that This antibody cross-reacts with some classical MHC Class I molecules (MHC Class Ia) : HLA-B7 (strongly), HLA-B8 (moderately), HLA-B27, -B44 (weakly).

Content And Storage:
Store at 4°C. Do not freeze.

Isotype:
IgG1

Img

Abnova Corporation

89-111-509

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Antigen:
BSG

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
BSG

Gene Symbols:
BSG

Immunogen:
Recombinant protein corresponding to human BSG.

Regulatory Status:
RUO

Gene ID (Entrez):
682

Target Species:
Human, Porcine

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry

Clone:
MEM-M6/2

Description:
Mouse monoclonal antibody raised against recombinant BSG.

Formulation:
In PBS, pH 7.4 (0.09% sodium azide)

Gene Alias:
5F7/CD147/EMMPRIN/M6/OK/TCSF

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes extracellular Ig domain D1 of BSG (Neurothelin), a 50-60 KDa type I transmembrane glycoprotein primarily expressed on all leukocytes, redblood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes. This antibody is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.

Content And Storage:
Store at 4°C. Do not freeze.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG2b