89-111-874
TP53, Mouse, FITC, Clone: BP53-12, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-111-874-Each-of-1 | In Stock | ₹ 51,079.32 |
89-111-874 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,079.32
GST (18%): ₹ 9,194.278
Total Price: ₹ 60,273.598
Antigen
TP53
Classification
Monoclonal
Concentration
1 mg/mL
Description
Mouse monoclonal antibody raised against recombinant TP53.
Formulation
In PBS, pH 7.2 (0.09% sodium azide)
Gene Alias
FLJ92943/LFS1/TRP53/p53
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
This antibody recognizes defined epitope (aa 16-25) on human p53, a 50 KDa tumour suppressor found in increased amounts in a wide variety of transformed cells.
Content And Storage
Store in the dark at 4°C. Do not freeze.Avoid prolonged exposure to light.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG2a
Applications
Flow Cytometry, Immunofluorescence
Clone
BP53-12
Conjugate
FITC
Dilution
The optimal working dilution should be determined by the end user.
Gene
TP53
Gene Symbols
TP53
Immunogen
Recombinant protein corresponding to full length human TP53.
Regulatory Status
RUO
Gene ID (Entrez)
7157
Target Species
Human, Non-human Primate
Form
Liquid
Related Products
Description
- This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism
- p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy
- p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains
- It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor
- Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity
- Alterations of this gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome
- Multiple p53 variants due to alternative promoters and multiple alternative splicing have been found
- These variants encode distinct isoforms, which can regulate p53 transcriptional activity
- [provided by RefSeq]
Compare Similar Items
Show Difference
Antigen: TP53
Classification: Monoclonal
Concentration: 1 mg/mL
Description: Mouse monoclonal antibody raised against recombinant TP53.
Formulation: In PBS, pH 7.2 (0.09% sodium azide)
Gene Alias: FLJ92943/LFS1/TRP53/p53
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This antibody recognizes defined epitope (aa 16-25) on human p53, a 50 KDa tumour suppressor found in increased amounts in a wide variety of transformed cells.
Content And Storage: Store in the dark at 4°C. Do not freeze.Avoid prolonged exposure to light.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG2a
Applications: Flow Cytometry, Immunofluorescence
Clone: BP53-12
Conjugate: FITC
Dilution: The optimal working dilution should be determined by the end user.
Gene: TP53
Gene Symbols: TP53
Immunogen: Recombinant protein corresponding to full length human TP53.
Regulatory Status: RUO
Gene ID (Entrez): 7157
Target Species: Human, Non-human Primate
Form: Liquid
Antigen:
TP53
Classification:
Monoclonal
Concentration:
1 mg/mL
Description:
Mouse monoclonal antibody raised against recombinant TP53.
Formulation:
In PBS, pH 7.2 (0.09% sodium azide)
Gene Alias:
FLJ92943/LFS1/TRP53/p53
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody recognizes defined epitope (aa 16-25) on human p53, a 50 KDa tumour suppressor found in increased amounts in a wide variety of transformed cells.
Content And Storage:
Store in the dark at 4°C. Do not freeze.Avoid prolonged exposure to light.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunofluorescence
Clone:
BP53-12
Conjugate:
FITC
Dilution:
The optimal working dilution should be determined by the end user.
Gene:
TP53
Gene Symbols:
TP53
Immunogen:
Recombinant protein corresponding to full length human TP53.
Regulatory Status:
RUO
Gene ID (Entrez):
7157
Target Species:
Human, Non-human Primate
Form:
Liquid
Antigen: FUT4
Classification: Monoclonal
Concentration: 1 mg/mL
Description: Mouse monoclonal antibody raised against native FUT4.
Formulation: In PBS, pH 7.2 (0.09% sodium azide)
Gene Alias: CD15/ELFT/FCT3A/FUC-TIV/FUTIV
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This antibody reacts with CD15, a cell membrane molecule 3-fucosyl-N-acetyllactosamine (3-FAL) strongly expressed on granulocytes, monocytes, macrophages, mast cells; it is also present on Langerhans cells and some myeloid precursors cells.
Content And Storage: Store at 4°C. Do not freeze.
Isotype: IgM
Applications: Flow Cytometry
Clone: MEM-158
Conjugate: Biotin
Dilution: Flow Cytometry (1:1000) The optimal working dilution should be determined by the end user.
Gene: FUT4
Gene Symbols: FUT4
Immunogen: Native purified FUT4 from human granulocytes.
Regulatory Status: RUO
Gene ID (Entrez): 2526
Target Species: Human
Form: Liquid
Antigen:
FUT4
Classification:
Monoclonal
Concentration:
1 mg/mL
Description:
Mouse monoclonal antibody raised against native FUT4.
Formulation:
In PBS, pH 7.2 (0.09% sodium azide)
Gene Alias:
CD15/ELFT/FCT3A/FUC-TIV/FUTIV
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody reacts with CD15, a cell membrane molecule 3-fucosyl-N-acetyllactosamine (3-FAL) strongly expressed on granulocytes, monocytes, macrophages, mast cells; it is also present on Langerhans cells and some myeloid precursors cells.
Content And Storage:
Store at 4°C. Do not freeze.
Isotype:
IgM
Applications:
Flow Cytometry
Clone:
MEM-158
Conjugate:
Biotin
Dilution:
Flow Cytometry (1:1000) The optimal working dilution should be determined by the end user.
Gene:
FUT4
Gene Symbols:
FUT4
Immunogen:
Native purified FUT4 from human granulocytes.
Regulatory Status:
RUO
Gene ID (Entrez):
2526
Target Species:
Human
Form:
Liquid
Antigen: CD7
Classification: Monoclonal
Concentration: __
Description: Mouse monoclonal antibody raised against native CD7.
Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
Gene Alias: GP40/LEU-9/TP41/Tp40
Host Species: Mouse
Quantity: 100 Reactions
Primary or Secondary: Primary
Test Specificity: The antibody reacts with CD7, a 40 KDa type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.
Content And Storage: Store in the dark at 4°C. Do not freeze.Avoid prolonged exposure to light.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG
Applications: Flow Cytometry
Clone: MEM-186
Conjugate: APC
Dilution: Flow Cytometry (10 ul in human blood cells 100 ul in whole blood or 106cells in a suspension) The optimal working dilution should be determined by the end user.
Gene: CD7
Gene Symbols: CD7
Immunogen: Native purified CD7 from human acute myelogenous leukaemia cell line KG-1.
Regulatory Status: RUO
Gene ID (Entrez): 924
Target Species: Human
Form: Liquid
Antigen:
CD7
Classification:
Monoclonal
Concentration:
__
Description:
Mouse monoclonal antibody raised against native CD7.
Formulation:
In PBS (0.2% BSA, 0.09% sodium azide)
Gene Alias:
GP40/LEU-9/TP41/Tp40
Host Species:
Mouse
Quantity:
100 Reactions
Primary or Secondary:
Primary
Test Specificity:
The antibody reacts with CD7, a 40 KDa type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.
Content And Storage:
Store in the dark at 4°C. Do not freeze.Avoid prolonged exposure to light.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG
Applications:
Flow Cytometry
Clone:
MEM-186
Conjugate:
APC
Dilution:
Flow Cytometry (10 ul in human blood cells 100 ul in whole blood or 106cells in a suspension) The optimal working dilution should be determined by the end user.
Gene:
CD7
Gene Symbols:
CD7
Immunogen:
Native purified CD7 from human acute myelogenous leukaemia cell line KG-1.
Regulatory Status:
RUO
Gene ID (Entrez):
924
Target Species:
Human
Form:
Liquid
Antigen: FCGR3B
Classification: Monoclonal
Concentration: __
Description: Mouse monoclonal antibody raised against native FCGR3B.
Formulation: In PBS, pH 7.2 (0.09% sodium azide)
Gene Alias: CD16/CD16b/FCG3/FCGR3
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This antibody reacts with the epitope on CD16 antigen that residing in proximity to FG loop (probably BC or C'E loop). This antibody reacts with CD16+ granulocytes.
Content And Storage: Store at 4°C. Do not freeze.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG1
Applications: Flow Cytometry
Clone: MEM-154
Conjugate: Biotin
Dilution: Flow Cytometry (1:500) The optimal working dilution should be determined by the end user.
Gene: FCGR3B
Gene Symbols: FCGR3B
Immunogen: Native purified FCGR3B from human granulocytes.
Regulatory Status: RUO
Gene ID (Entrez): 2215
Target Species: Human
Form: Liquid
Antigen:
FCGR3B
Classification:
Monoclonal
Concentration:
__
Description:
Mouse monoclonal antibody raised against native FCGR3B.
Formulation:
In PBS, pH 7.2 (0.09% sodium azide)
Gene Alias:
CD16/CD16b/FCG3/FCGR3
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody reacts with the epitope on CD16 antigen that residing in proximity to FG loop (probably BC or C'E loop). This antibody reacts with CD16+ granulocytes.
Content And Storage:
Store at 4°C. Do not freeze.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
MEM-154
Conjugate:
Biotin
Dilution:
Flow Cytometry (1:500) The optimal working dilution should be determined by the end user.
Gene:
FCGR3B
Gene Symbols:
FCGR3B
Immunogen:
Native purified FCGR3B from human granulocytes.
Regulatory Status:
RUO
Gene ID (Entrez):
2215
Target Species:
Human
Form:
Liquid