KLKB1, Mouse, Clone: 901, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-111-991-Each-of-1 | In Stock | ₹ 2,42,134.80 |
89-111-991 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 2,42,134.80
GST (18%): ₹ 43,584.264
Total Price: ₹ 2,85,719.064
Antigen
KLKB1
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
The optimal working dilution should be determined by the end user.
Gene
KLKB1
Gene Symbols
KLKB1
Immunogen
Native purified human plasma KLKB1 (Heavy Chain).
Regulatory Status
RUO
Gene ID (Entrez)
3818
Target Species
Baboon, Chimpanzee, Human, Monkey
Form
Liquid
Applications
ELISA, Western Blot
Clone
901
Description
Mouse monoclonal antibody raised against native KLKB1 (Heavy Chain).
Formulation
In PBS, pH 7.4
Gene Alias
KLK3/PPK
Host Species
Mouse
Quantity
200 μg
Primary or Secondary
Primary
Test Specificity
Recognizes two variants (88 KDa and 85 KDa) of prekallikrein and its activation products kallikrein (88 KDa and 85 KDa), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and Antithrombin III, and 45 KDa prekallikrein/kallikrein fragment(s). Recognizes prekallikrein and its activation products in human, chimpanzee, rhesus, and baboon plasmas. The epitope for this antibody, located on the prekallikrein/kallikrein heavy chain, is involved in the interaction between prekallikrein and factor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by approximately 60-80% and 55%, respectively. This antibody does not cross-react with tissue kallikrein.
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1
Related Products
Description
- Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation
- It is synthesized in the liver and secreted into the blood as a single polypeptide chain
- Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond
- Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond
- The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids
- Each repeat harbors a novel structure called the apple domain
- The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein
- The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases
- Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients
- [provided by RefSeq
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Antigen: KLKB1
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: The optimal working dilution should be determined by the end user.
Gene: KLKB1
Gene Symbols: KLKB1
Immunogen: Native purified human plasma KLKB1 (Heavy Chain).
Regulatory Status: RUO
Gene ID (Entrez): 3818
Target Species: Baboon, Chimpanzee, Human, Monkey
Form: Liquid
Applications: ELISA, Western Blot
Clone: 901
Description: Mouse monoclonal antibody raised against native KLKB1 (Heavy Chain).
Formulation: In PBS, pH 7.4
Gene Alias: KLK3/PPK
Host Species: Mouse
Quantity: 200 μg
Primary or Secondary: Primary
Test Specificity: Recognizes two variants (88 KDa and 85 KDa) of prekallikrein and its activation products kallikrein (88 KDa and 85 KDa), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and Antithrombin III, and 45 KDa prekallikrein/kallikrein fragment(s). Recognizes prekallikrein and its activation products in human, chimpanzee, rhesus, and baboon plasmas. The epitope for this antibody, located on the prekallikrein/kallikrein heavy chain, is involved in the interaction between prekallikrein and factor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by approximately 60-80% and 55%, respectively. This antibody does not cross-react with tissue kallikrein.
Content And Storage: Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG1
Antigen: CFB
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Sandwich ELISA (1:1000) The optimal working dilution should be determined by the end user.
Gene: CFB
Gene Symbols: CFB
Immunogen: Native purified human IL1R1.
Regulatory Status: RUO
Gene ID (Entrez): 629
Target Species: Human
Form: Liquid
Applications: ELISA
Clone: KT24
Description: Mouse monoclonal antibody raised against native CFB
Formulation: In PBS (0.09% sodium azide)
Gene Alias: BF/BFD/CFAB/FB/FBI12/GBG/H2-Bf/PBF2
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG1
Antigen: TNFRSF1B
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: ELISA (1 ug/mL) The optimal working dilution should be determined by the end user.
Gene: TNFRSF1B
Gene Symbols: TNFRSF1B
Immunogen: Recombinant protein corresponding to human TNFRSF1B.
Regulatory Status: RUO
Gene ID (Entrez): 7133
Target Species: Human
Form: Liquid
Applications: ELISA
Clone: KT30
Description: Mouse monoclonal antibody raised against recombinant TNFRSF1B.
Formulation: In PBS (0.09% sodium azide)
Gene Alias: CD120b/TBPII/TNF-R-II/TNF-R75/TNFBR/TNFR1B/TNFR2/TNFR80/p75/p75TNFR
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Store at 4°C. For long term storage store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG2a