89-112-164
HLA-B, Mouse, Clone: EP-4, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-112-164-Each-of-1 | In Stock | ₹ 45,517.92 |
89-112-164 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,517.92
GST (18%): ₹ 8,193.226
Total Price: ₹ 53,711.146
Antigen
HLA-B
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
The optimal working dilution should be determined by the end user.
Gene
HLA-B
Gene Symbols
HLA-B
Immunogen
Native purified from lymphocytes of HLA-B27 individual.
Regulatory Status
RUO
Gene ID (Entrez)
3106
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry
Clone
EP-4
Description
Mouse monoclonal antibody raised against native HLA-B.
Formulation
In PBS (0.05% sodium azide)
Gene Alias
AS/HLA-B-7301/HLA-B73/HLAB/HLAC/SPDA1
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
EP-4 recognizes the HLA-B27 cell surface antigen on human cells. Since EP-4 recognizes the HLA-B27 antigen, it may be used to HLA type human lymphoctyes. Approximately 60% of patients with ankylosing spondylitis are HLA-B27 positive. This reagent can be used to help identify this HLA haplotype in human lymphocytes. Monoclonal antibody EP-4 recognizes the HLA-B27 antigen expressed on individuals with this HLA haplotype.
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgM κ
Related Products
Description
- HLA-B belongs to the HLA class I heavy chain paralogues
- This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin)
- The heavy chain is anchored in the membrane
- Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen
- They are expressed in nearly all cells
- The heavy chain is approximately 45kDa and its gene contains 8 exons
- Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail
- Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule
- Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
- Hundreds of HLA-B alleles have been described
- [provided by RefSeq
Compare Similar Items
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Antigen: HLA-B
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: The optimal working dilution should be determined by the end user.
Gene: HLA-B
Gene Symbols: HLA-B
Immunogen: Native purified from lymphocytes of HLA-B27 individual.
Regulatory Status: RUO
Gene ID (Entrez): 3106
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry
Clone: EP-4
Description: Mouse monoclonal antibody raised against native HLA-B.
Formulation: In PBS (0.05% sodium azide)
Gene Alias: AS/HLA-B-7301/HLA-B73/HLAB/HLAC/SPDA1
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: EP-4 recognizes the HLA-B27 cell surface antigen on human cells. Since EP-4 recognizes the HLA-B27 antigen, it may be used to HLA type human lymphoctyes. Approximately 60% of patients with ankylosing spondylitis are HLA-B27 positive. This reagent can be used to help identify this HLA haplotype in human lymphocytes. Monoclonal antibody EP-4 recognizes the HLA-B27 antigen expressed on individuals with this HLA haplotype.
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgM κ
Antigen:
HLA-B
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
The optimal working dilution should be determined by the end user.
Gene:
HLA-B
Gene Symbols:
HLA-B
Immunogen:
Native purified from lymphocytes of HLA-B27 individual.
Regulatory Status:
RUO
Gene ID (Entrez):
3106
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry
Clone:
EP-4
Description:
Mouse monoclonal antibody raised against native HLA-B.
Formulation:
In PBS (0.05% sodium azide)
Gene Alias:
AS/HLA-B-7301/HLA-B73/HLAB/HLAC/SPDA1
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
EP-4 recognizes the HLA-B27 cell surface antigen on human cells. Since EP-4 recognizes the HLA-B27 antigen, it may be used to HLA type human lymphoctyes. Approximately 60% of patients with ankylosing spondylitis are HLA-B27 positive. This reagent can be used to help identify this HLA haplotype in human lymphocytes. Monoclonal antibody EP-4 recognizes the HLA-B27 antigen expressed on individuals with this HLA haplotype.
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgM κ
Antigen: VTN
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: The optimal working dilution should be determined by the end user.
Gene: VTN
Gene Symbols: VTN
Immunogen: Native purified VTN from human peripheral lymphocytes.
Regulatory Status: RUO
Gene ID (Entrez): 7448
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot
Clone: RIV12
Description: Mouse monoclonal antibody raised against native VTN.
Formulation: In PBS (0.05% sodium azide)
Gene Alias: V75/VN/VNT
Host Species: Mouse
Quantity: 1 mL
Primary or Secondary: Primary
Test Specificity: RIV12, selected by ELISA, cytotoxicity tests and FACS analysis appeared to be an /CD1 reacting with a 49 KDa molecule on human thymocytes. Splenocytes of the mouse were fused with mouse myeloma cells of the 653 cell line.
Content And Storage: Store at 4°C.
Isotype: IgG
Antigen:
VTN
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
The optimal working dilution should be determined by the end user.
Gene:
VTN
Gene Symbols:
VTN
Immunogen:
Native purified VTN from human peripheral lymphocytes.
Regulatory Status:
RUO
Gene ID (Entrez):
7448
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot
Clone:
RIV12
Description:
Mouse monoclonal antibody raised against native VTN.
Formulation:
In PBS (0.05% sodium azide)
Gene Alias:
V75/VN/VNT
Host Species:
Mouse
Quantity:
1 mL
Primary or Secondary:
Primary
Test Specificity:
RIV12, selected by ELISA, cytotoxicity tests and FACS analysis appeared to be an /CD1 reacting with a 49 KDa molecule on human thymocytes. Splenocytes of the mouse were fused with mouse myeloma cells of the 653 cell line.
Content And Storage:
Store at 4°C.
Isotype:
IgG
Antigen: CD28
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: The optimal working dilution should be determined by the end user.
Gene: CD28
Gene Symbols: CD28
Immunogen: Native purified CD28 from stimulated human leucocytes.
Regulatory Status: RUO
Gene ID (Entrez): 940
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Frozen)
Clone: 204-12
Description: Mouse monoclonal antibody raised against native CD28.
Formulation: In PBS (0.05% sodium azide)
Gene Alias: MGC138290/Tp44
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: 204-12 remained unassigned at the VI international workshop on human leucocyte differentiation antigens. Splenocytes were fused with NS1.
Content And Storage: Store at 4°C.
Isotype: IgG2a
Antigen:
CD28
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
The optimal working dilution should be determined by the end user.
Gene:
CD28
Gene Symbols:
CD28
Immunogen:
Native purified CD28 from stimulated human leucocytes.
Regulatory Status:
RUO
Gene ID (Entrez):
940
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Frozen)
Clone:
204-12
Description:
Mouse monoclonal antibody raised against native CD28.
Formulation:
In PBS (0.05% sodium azide)
Gene Alias:
MGC138290/Tp44
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
204-12 remained unassigned at the VI international workshop on human leucocyte differentiation antigens. Splenocytes were fused with NS1.
Content And Storage:
Store at 4°C.
Isotype:
IgG2a
Antigen: IGSF2
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Flow Cytometry (10ul of the suggested working dilution (1:50-1:100) to label 106cells in 100ul) The optimal working dilution should be determined by the end user.
Gene: IGSF2
Gene Symbols: IGSF2
Immunogen: Human thymic clone B12.
Regulatory Status: RUO
Gene ID (Entrez): 9398
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone: BB27
Description: Mouse monoclonal antibody raised against IGSF2.
Formulation: In PBS, pH 7.4 (0.09% sodium azide)
Gene Alias: CD101/V7
Host Species: Mouse
Quantity: 200 μg
Primary or Secondary: Primary
Test Specificity: This antibody recognizes human CD101. CD101 is a 140kD homodimeric cell surface glycoprotein expressed primarily by monocytes, granulocytes, dendritic cells and activated T lymphocytes. Removal of sodium azide is recommended prior to use in functional assays.
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG1
Antigen:
IGSF2
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Flow Cytometry (10ul of the suggested working dilution (1:50-1:100) to label 106cells in 100ul) The optimal working dilution should be determined by the end user.
Gene:
IGSF2
Gene Symbols:
IGSF2
Immunogen:
Human thymic clone B12.
Regulatory Status:
RUO
Gene ID (Entrez):
9398
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone:
BB27
Description:
Mouse monoclonal antibody raised against IGSF2.
Formulation:
In PBS, pH 7.4 (0.09% sodium azide)
Gene Alias:
CD101/V7
Host Species:
Mouse
Quantity:
200 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody recognizes human CD101. CD101 is a 140kD homodimeric cell surface glycoprotein expressed primarily by monocytes, granulocytes, dendritic cells and activated T lymphocytes. Removal of sodium azide is recommended prior to use in functional assays.
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG1