89-112-221
AFP, Mouse, Clone: D10, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-112-221-Each-of-1 | In Stock | ₹ 55,100.64 |
89-112-221 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,100.64
GST (18%): ₹ 9,918.115
Total Price: ₹ 65,018.755
Antigen
AFP
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
The optimal working dilution should be determined by the end user.
Gene
AFP
Gene Symbols
AFP
Immunogen
Native AFP purified from serum of hepatoma patients.
Regulatory Status
RUO
Gene ID (Entrez)
174
Target Species
Human
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
Clone
D10
Description
Mouse monoclonal antibody raised against native AFP.
Formulation
In PBS (0.05% sodium azide)
Gene Alias
FETA/HPAFP
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
D10 has been characterized in the ISOBM TD-2 workshop and assigned by K. Nustad to group D of a cluster of 6 major epitopes of human alpha fetoprotein. human alpha fetoprotein is an oncofetal protein of 70 kD. Its gene has been cloned and sequenced and its structure identified. AFP is expressed in fetal liver and is normally absent in healthy adult tissues. It is expressed in all yolk sac tumors, in some germ cell tumors and in hepatocellular carcinomas.
Content And Storage
Store at 4°C.
Isotype
IgG1
Related Products
Description
- This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life
- Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma
- However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology
- The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4
- Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin
- The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly
- [provided by RefSeq
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Antigen: AFP
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: The optimal working dilution should be determined by the end user.
Gene: AFP
Gene Symbols: AFP
Immunogen: Native AFP purified from serum of hepatoma patients.
Regulatory Status: RUO
Gene ID (Entrez): 174
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
Clone: D10
Description: Mouse monoclonal antibody raised against native AFP.
Formulation: In PBS (0.05% sodium azide)
Gene Alias: FETA/HPAFP
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: D10 has been characterized in the ISOBM TD-2 workshop and assigned by K. Nustad to group D of a cluster of 6 major epitopes of human alpha fetoprotein. human alpha fetoprotein is an oncofetal protein of 70 kD. Its gene has been cloned and sequenced and its structure identified. AFP is expressed in fetal liver and is normally absent in healthy adult tissues. It is expressed in all yolk sac tumors, in some germ cell tumors and in hepatocellular carcinomas.
Content And Storage: Store at 4°C.
Isotype: IgG1
Antigen:
AFP
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
The optimal working dilution should be determined by the end user.
Gene:
AFP
Gene Symbols:
AFP
Immunogen:
Native AFP purified from serum of hepatoma patients.
Regulatory Status:
RUO
Gene ID (Entrez):
174
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
Clone:
D10
Description:
Mouse monoclonal antibody raised against native AFP.
Formulation:
In PBS (0.05% sodium azide)
Gene Alias:
FETA/HPAFP
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
D10 has been characterized in the ISOBM TD-2 workshop and assigned by K. Nustad to group D of a cluster of 6 major epitopes of human alpha fetoprotein. human alpha fetoprotein is an oncofetal protein of 70 kD. Its gene has been cloned and sequenced and its structure identified. AFP is expressed in fetal liver and is normally absent in healthy adult tissues. It is expressed in all yolk sac tumors, in some germ cell tumors and in hepatocellular carcinomas.
Content And Storage:
Store at 4°C.
Isotype:
IgG1
Antigen: Aqp1
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Immunohistochemistry (Frozen sections) (1:500-1:1000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000) ELISA (1:1000-1:20000) Immunoprecipitation (1:1000-1:10000) Western Blot (1:1000-1:10000) The optimal
Gene: Aqp1
Gene Symbols: Aqp1
Immunogen: A synthetic peptide corresponding to amino acids 249-269 of rat Aqp1.
Regulatory Status: RUO
Gene ID (Entrez): 25240
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone: 1/A5F6
Description: Mouse monoclonal antibody raised against synthetic peptide of Aqp1.
Formulation: In PBS (0.09% sodium azide, 0.1% BSA)
Gene Alias: CHIP28
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: The monoclonal antibody recognizes an epitope within the cytoplasmic domain of the water-specific channel aquaporin 1 (also known as AQP1 or CHIP-28). Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and the kidney. AQP1 is also expressed by the choroid plexus and various other tissues. The glycosylated forms of AQP1 range between 40-60kD in mass.
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG1
Antigen:
Aqp1
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Immunohistochemistry (Frozen sections) (1:500-1:1000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000) ELISA (1:1000-1:20000) Immunoprecipitation (1:1000-1:10000) Western Blot (1:1000-1:10000) The optimal
Gene:
Aqp1
Gene Symbols:
Aqp1
Immunogen:
A synthetic peptide corresponding to amino acids 249-269 of rat Aqp1.
Regulatory Status:
RUO
Gene ID (Entrez):
25240
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone:
1/A5F6
Description:
Mouse monoclonal antibody raised against synthetic peptide of Aqp1.
Formulation:
In PBS (0.09% sodium azide, 0.1% BSA)
Gene Alias:
CHIP28
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
The monoclonal antibody recognizes an epitope within the cytoplasmic domain of the water-specific channel aquaporin 1 (also known as AQP1 or CHIP-28). Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and the kidney. AQP1 is also expressed by the choroid plexus and various other tissues. The glycosylated forms of AQP1 range between 40-60kD in mass.
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG1
Antigen: C5AR1
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Flow Cytometry (10 ul of the suggested dilution (1:50-1:100) to label 5 x 105cells in 100 ul) The optimal working dilution should be determined by the end user.
Gene: C5AR1
Gene Symbols: C5AR1
Immunogen: A synthetic peptide corresponding to N-terminus extracellular domain (met1-Asn31) of human C5AR1.
Regulatory Status: RUO
Gene ID (Entrez): 728
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry, Western Blot
Clone: S5/1
Description: Mouse monoclonal antibody raised against synthetic peptide of C5AR1.
Formulation: In PBS (0.09% sodium azide)
Gene Alias: C5A/C5AR/C5R1/CD88
Host Species: Mouse
Quantity: 200 μg
Primary or Secondary: Primary
Test Specificity: This antibody recognizes the C5a receptor (C5aR) CD88, which is predominantly expressed on cells of the myeloid lineage. Clone S5/1 was raised against a synthetic peptide comprising the Nterminal extracellular domain of the C5aR (met1-Asn31) and has recently been shown to recognize the heptameric peptide (D15DKDTLD21). Clone S5/1 has been shown to inhibit the binding of C5a to its receptor. Serotec recommend the use of the monoclonal antibody for functional studies. Cross reacts with human.
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG2a
Antigen:
C5AR1
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Flow Cytometry (10 ul of the suggested dilution (1:50-1:100) to label 5 x 105cells in 100 ul) The optimal working dilution should be determined by the end user.
Gene:
C5AR1
Gene Symbols:
C5AR1
Immunogen:
A synthetic peptide corresponding to N-terminus extracellular domain (met1-Asn31) of human C5AR1.
Regulatory Status:
RUO
Gene ID (Entrez):
728
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry, Western Blot
Clone:
S5/1
Description:
Mouse monoclonal antibody raised against synthetic peptide of C5AR1.
Formulation:
In PBS (0.09% sodium azide)
Gene Alias:
C5A/C5AR/C5R1/CD88
Host Species:
Mouse
Quantity:
200 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody recognizes the C5a receptor (C5aR) CD88, which is predominantly expressed on cells of the myeloid lineage. Clone S5/1 was raised against a synthetic peptide comprising the Nterminal extracellular domain of the C5aR (met1-Asn31) and has recently been shown to recognize the heptameric peptide (D15DKDTLD21). Clone S5/1 has been shown to inhibit the binding of C5a to its receptor. Serotec recommend the use of the monoclonal antibody for functional studies. Cross reacts with human.
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG2a
Antigen: GZMA
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200) The optimal working dilution should be determined by the end user.
Gene: GZMA
Gene Symbols: GZMA
Immunogen: Recombinant protein corresponding to human GZMA.
Regulatory Status: RUO
Gene ID (Entrez): 3001
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Clone: GA6
Description: Mouse monoclonal antibody raised against recombinant GZMA.
Formulation: In Tris (0.09% sodium azide)
Gene Alias: CTLA3/HFSP
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This antibody recognizes Granzyme A, a 60kD disulphide-linked homodimeric protein expressed in cytoplasmic granules of cytotoxic lymphocytes. The biological function of Granzyme A is unclear. It would appear that the molecule may have a role in the induction of apoptosis via its activity as a serine protease, but this would seem to be subsidiary to the role of Granzyme B. Granzyme A deficient mice are indistinguishable from normal animals in their response to infection.
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG1
Antigen:
GZMA
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200) The optimal working dilution should be determined by the end user.
Gene:
GZMA
Gene Symbols:
GZMA
Immunogen:
Recombinant protein corresponding to human GZMA.
Regulatory Status:
RUO
Gene ID (Entrez):
3001
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Clone:
GA6
Description:
Mouse monoclonal antibody raised against recombinant GZMA.
Formulation:
In Tris (0.09% sodium azide)
Gene Alias:
CTLA3/HFSP
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody recognizes Granzyme A, a 60kD disulphide-linked homodimeric protein expressed in cytoplasmic granules of cytotoxic lymphocytes. The biological function of Granzyme A is unclear. It would appear that the molecule may have a role in the induction of apoptosis via its activity as a serine protease, but this would seem to be subsidiary to the role of Granzyme B. Granzyme A deficient mice are indistinguishable from normal animals in their response to infection.
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG1