89-112-713

BRCA1 Mouse anti-Human, Monoclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-112-713-Each-of-1 In Stock ₹ 1,11,228.00

89-112-713 - Each of 1

₹ 1,11,228.00

In Stock

Quantity

1

Base Price: ₹ 1,11,228.00

GST (18%): ₹ 20,021.04

Total Price: ₹ 1,31,249.04

Antigen

BRCA1

Classification

Monoclonal

Description

Mouse monoclonal antibody raised against partial recombinant BRCA1.

Formulation

In PBS, pH 7.4

Gene Alias

BRCAI/BRCC1/IRIS/PSCP/RNF53

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein, and does not recognize the Deltaexon 11 splice variant.

Content And Storage

Store at -80°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1 κ

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1-10 ug/mL) Immunoprecipitation (1-10 ug/mL) Immunohistochemistry (1-10 ug/mL) The optimal working dilution should be determined by the end user.

Gene

BRCA1

Gene Symbols

BRCA1

Immunogen

Recombinant GST fusion protein corresponding to amino acids 762-1315 of human BRCA1.

Regulatory Status

RUO

Gene ID (Entrez)

672

Target Species

Human

Form

Liquid

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Description

  • This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor
  • The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC)
  • This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes
  • This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination
  • Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers
  • Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene
  • Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described
  • A related pseudogene, which is also located on chromosome 17, has been identified
  • [provided by RefSeq

Compare Similar Items

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Abnova Corporation

89-112-713

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Antigen:
BRCA1

Classification:
Monoclonal

Description:
Mouse monoclonal antibody raised against partial recombinant BRCA1.

Formulation:
In PBS, pH 7.4

Gene Alias:
BRCAI/BRCC1/IRIS/PSCP/RNF53

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein, and does not recognize the Deltaexon 11 splice variant.

Content And Storage:
Store at -80°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1-10 ug/mL) Immunoprecipitation (1-10 ug/mL) Immunohistochemistry (1-10 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
BRCA1

Gene Symbols:
BRCA1

Immunogen:
Recombinant GST fusion protein corresponding to amino acids 762-1315 of human BRCA1.

Regulatory Status:
RUO

Gene ID (Entrez):
672

Target Species:
Human

Form:
Liquid

Img

Abnova Corporation

89-112-714

--


Antigen:
CENPF

Classification:
Monoclonal

Description:
Mouse monoclonal antibody raised against partial recombinant CENPF.

Formulation:
In PBS, pH 7.4

Gene Alias:
CENF/PRO1779/hcp-1

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes mitosin, a 350 kD phosphoprotein that is specifically involved in mitotic-phase progression.

Content And Storage:
Store at -80°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG2a κ

Applications:
Immunohistochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1-10 ug/mL) Immunoprecipitation (1-10 ug/mL) Immunohistochemistry (Frozen sections) (10 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) The optimal working dilution should be determined by t

Gene:
CENPF

Gene Symbols:
CENPF

Immunogen:
Recombinant GST fusion protein corresponding to amino acids 1759-2093 of human CENPF.

Regulatory Status:
RUO

Gene ID (Entrez):
1063

Target Species:
Human

Form:
Liquid

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89-112-716

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Antigen:
HSPA4/HSPA8

Classification:
Monoclonal

Description:
Mouse monoclonal antibody raised against recombinant HSPA4/HSPA8.

Formulation:
In PBS, pH 7.4 (0.09% sodium azide)

Gene Alias:
APG-2/HS24/P52/MGC131852/RY/hsp70/hsp70RY

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
The epitope is in the region of amino acids 503-640 of human Hsp70.

Content And Storage:
Store at 4°C. Do not freeze.

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1 ug/mL) Immunohistochemistry (1-10 ug/mL) Immunoprecipitation (1-10 ug/mL) Flow cytometry (10 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
__

Gene Symbols:
HSPA4

Immunogen:
Recombinant protein corresponding to human HSPA4/HSPA8.

Regulatory Status:
RUO

Gene ID (Entrez):
3308/3312

Target Species:
Bovine, Canine, Chicken, Drosophila, Fish, Frog, Guinea Pig, Hamster, Human, Monkey, Mouse, Nematode, Plant, Porcine, Rabbit, Rat, Sheep

Form:
Liquid

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Abnova Corporation

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Antigen:
SERPINA1

Classification:
Monoclonal

Description:
Mouse monoclonal antibody raised against native SERPINA1.

Formulation:
In PBS, pH 7.4

Gene Alias:
A1A/A1AT/AAT/MGC23330/MGC9222/PI/PI1/PRO2275

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
These antibodies specifically recognize alpha-1-antitrypsin. They do not cross-react with alpha-1-antichymotrypsin.

Content And Storage:
Store at -80°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

Applications:
ELISA, Immunofluorescence

Conjugate:
Unconjugated

Dilution:
The optimal working dilution should be determined by the end user.

Gene:
SERPINA1

Gene Symbols:
SERPINA1

Immunogen:
Native purified SERPINA1 from human serum.

Regulatory Status:
RUO

Gene ID (Entrez):
5265

Target Species:
Human

Form:
Liquid