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89-114-454

CDKN2A Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-114-454-Each-of-1 In Stock ₹ 51,079.32

89-114-454 - Each of 1

₹ 51,079.32

In Stock

Quantity

1

Base Price: ₹ 51,079.32

GST (18%): ₹ 9,194.278

Total Price: ₹ 60,273.598

Antigen

CDKN2A

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against a synthetic peptide of CDKN2A.

Formulation

In PBS (0.2% gelatin, 0.09% sodium azide)

Gene Alias

ARF/CDK4I/CDKN2/CMM2/INK4/INK4a/MLM/MTS1/TP16/p14/p14ARF/p16/p16INK4/p16INK4a/p19

Host Species

Rabbit

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (PFA fixed), Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1:200) The optimal working dilution should be determined by the end user.

Gene

CDKN2A

Gene Symbols

CDKN2A

Immunogen

A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CDKN2A.

Regulatory Status

RUO

Gene ID (Entrez)

1029

Content And Storage

Store at 4°C. Do not freeze.

Description

  • This gene generates several transcript variants which differ in their first exons
  • At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase
  • The remaining transcript includes an alternate first exon located 20kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants
  • This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, MDM1, a protein responsible for the degradation of p53
  • In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control
  • This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene
  • [provided by RefSeq

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Abnova Corporation

89-114-454

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Antigen:
CDKN2A
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against a synthetic peptide of CDKN2A.
Formulation:
In PBS (0.2% gelatin, 0.09% sodium azide)
Gene Alias:
ARF/CDK4I/CDKN2/CMM2/INK4/INK4a/MLM/MTS1/TP16/p14/p14ARF/p16/p16INK4/p16INK4a/p19
Host Species:
Rabbit
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (PFA fixed), Western Blot
Conjugate:
Unconjugated
Dilution:
Western Blot (1:200) The optimal working dilution should be determined by the end user.
Gene:
CDKN2A
Gene Symbols:
CDKN2A
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CDKN2A.
Regulatory Status:
RUO
Gene ID (Entrez):
1029
Content And Storage:
Store at 4°C. Do not freeze.

Img

Abnova Corporation

89-114-455

--

Antigen:
Mapk3
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against a synthetic peptide of Mapk3.
Formulation:
In PBS (0.2% gelatin, 0.09% sodium azide)
Gene Alias:
ERK1/Erk-1/Esrk1/Prkm3/p44/p44erk1/p44mapk
Host Species:
Rabbit
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Rat
Form:
Liquid
Applications:
Western Blot
Conjugate:
Unconjugated
Dilution:
Western Blot (1:200) The optimal working dilution should be determined by the end user.
Gene:
Mapk3
Gene Symbols:
Mapk3
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to the subdomain XI of rat Mapk3.
Regulatory Status:
RUO
Gene ID (Entrez):
50689
Content And Storage:
Store at 4°C. Do not freeze.

Img

Abnova Corporation

89-114-456

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Antigen:
Mapk1
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against a synthetic peptide of Mapk1.
Formulation:
In PBS (0.2% gelatin, 0.09% sodium azide)
Gene Alias:
Erk2
Host Species:
Rabbit
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Rat
Form:
Liquid
Applications:
Western Blot
Conjugate:
Unconjugated
Dilution:
Western Blot (1:400) The optimal working dilution should be determined by the end user.
Gene:
Mapk1
Gene Symbols:
Mapk1
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of rat Mapk1.
Regulatory Status:
RUO
Gene ID (Entrez):
116590
Content And Storage:
Store at 4°C. Do not freeze.

Img

Abnova Corporation

89-114-457

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Antigen:
Mapk14
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against a synthetic peptide of Mapk14.
Formulation:
In PBS (0.2% gelatin, 0.09% sodium azide)
Gene Alias:
CSBP2/Crk1/Csbp1/MGC102436/Mxi2/PRKM14/PRKM15/p38/p38-alpha/p38MAPK/p38a/p38alpha
Host Species:
Rabbit
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Western Blot
Conjugate:
Unconjugated
Dilution:
Western Blot (1:200) The optimal working dilution should be determined by the end user.
Gene:
Mapk14
Gene Symbols:
Mapk14
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of mouse Mapk14.
Regulatory Status:
RUO
Gene ID (Entrez):
26416
Content And Storage:
Store at 4°C. Do not freeze.