89-114-762

NOTCH1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-114-762-Each-of-1 In Stock ₹ 98,394.00

89-114-762 - Each of 1

₹ 98,394.00

In Stock

Quantity

1

Base Price: ₹ 98,394.00

GST (18%): ₹ 17,710.92

Total Price: ₹ 1,16,104.92

Antigen

NOTCH1

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of NOTCH1.

Formulation

In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.1% sodium azide)

Gene Alias

TAN1/hN1

Host Species

Rabbit

Quantity

200 μL

Primary or Secondary

Primary

Test Specificity

This antiserum is directed against human NOTCH 1. Only the cleaved intracellular (activated) form (NICD) is detected. No reactivity is detected against mouse N2, N3 or N4. The immunogen epitope is only exposed after gamma secretase cleavage and is not accessible in the uncleaved form.

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Dilution

Sandwich ELISA (1:20000-1:60000) Western Blot (1:500) The optimal working dilution should be determined by the end user.

Gene

NOTCH1

Gene Symbols

NOTCH1

Immunogen

A synthetic peptide corresponding to N-terminus the cleaved N intracellular domain (NICD) of human NOTCH1.

Regulatory Status

RUO

Gene ID (Entrez)

4851

Target Species

Human, Mouse, Rat

Form

Liquid

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Description

  • Description This gene encodes a member of the Notch family
  • Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types
  • Notch family members play a role in a variety of developmental processes by controlling cell fate decisions
  • The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells
  • In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development
  • Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined
  • This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer
  • This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development
  • [provided by RefSeq

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Img

Abnova Corporation

89-114-762

--


Antigen:
NOTCH1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of NOTCH1.

Formulation:
In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.1% sodium azide)

Gene Alias:
TAN1/hN1

Host Species:
Rabbit

Quantity:
200 μL

Primary or Secondary:
Primary

Test Specificity:
This antiserum is directed against human NOTCH 1. Only the cleaved intracellular (activated) form (NICD) is detected. No reactivity is detected against mouse N2, N3 or N4. The immunogen epitope is only exposed after gamma secretase cleavage and is not accessible in the uncleaved form.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Dilution:
Sandwich ELISA (1:20000-1:60000) Western Blot (1:500) The optimal working dilution should be determined by the end user.

Gene:
NOTCH1

Gene Symbols:
NOTCH1

Immunogen:
A synthetic peptide corresponding to N-terminus the cleaved N intracellular domain (NICD) of human NOTCH1.

Regulatory Status:
RUO

Gene ID (Entrez):
4851

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Abnova Corporation

89-114-763

--


Antigen:
NOTCH1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of NOTCH1.

Formulation:
In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide)

Gene Alias:
TAN1/hN1

Host Species:
Rabbit

Quantity:
200 μL

Primary or Secondary:
Primary

Test Specificity:
This antiserum is directed against human NOTCH 1. No reaction is detected against NOTCH 2. No reactivity was observed against Mouse Notch.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
ELISA (1:20000-1:100000) Western Blot (1:2000-1:10000) Immunohistochemistry (1:1000-1:5000) The optimal working dilution should be determined by the end user.

Gene:
NOTCH1

Gene Symbols:
NOTCH1

Immunogen:
A synthetic peptide corresponding to amino acids 2488-2502 of human NOTCH1.

Regulatory Status:
RUO

Gene ID (Entrez):
4851

Target Species:
Human

Form:
Liquid

Img

Abnova Corporation

89-114-767

--


Antigen:
POU5F1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of POU5F1.

Formulation:
In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide)

Gene Alias:
MGC22487/OCT3/OCT4/OTF3/OTF4

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody reacts with human and mouse Oct-4 protein.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
ELISA (1:350000) Western Blot (1:1000-1:1500) The optimal working dilution should be determined by the end user.

Gene:
POU5F1

Gene Symbols:
POU5F1

Immunogen:
A synthetic peptide corresponding to internal region of human POU5F1.

Regulatory Status:
RUO

Gene ID (Entrez):
5460

Target Species:
Human

Form:
Liquid

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Abnova Corporation

89-114-772

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Antigen:
RPS6KB1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of RPS6KB1.

Formulation:
In 100mM Tris-Cl, 500mM NaCl, pH 8.0 (0.01% sodium azide)

Gene Alias:
PS6K/S6K/S6K1/STK14A/p70(S6K)-alpha/p70-S6K/p70-alpha

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This affinity-purified antibody is directed against the human p70S6K protein.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
ELISA (1:5000) Western Blot (1:1000) Immunoprecipitation (5 ug/mg protein sample) The optimal working dilution should be determined by the end user.

Gene:
RPS6KB1

Gene Symbols:
RPS6KB1

Immunogen:
A synthetic peptide corresponding to C-terminus human RPS6KB1.

Regulatory Status:
RUO

Gene ID (Entrez):
6198

Target Species:
Human, Mouse, Rat

Form:
Liquid