89-115-974

TP53 (phospho S15), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-115-974-Each-of-1 In Stock ₹ 54,929.52

89-115-974 - Each of 1

₹ 54,929.52

In Stock

Quantity

1

Base Price: ₹ 54,929.52

GST (18%): ₹ 9,887.314

Total Price: ₹ 64,816.834

Antigen

TP53

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of TP53.

Formulation

In TBS, pH 7.2 (BSA, 10% Proclin300)

Gene Alias

FLJ92943/LFS1/TRP53/p53

Host Species

Rabbit

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody recognizes ∼53 KDa of human TP53. It does not recognize non-phosphorylated peptides.

Content And Storage

Store at 4°C. For long term storage store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG

Applications

ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (2-5 ug/mL) The optimal working dilution should be determined by the end user.

Gene

TP53

Gene Symbols

TP53

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding S15 of human TP53.

Regulatory Status

RUO

Gene ID (Entrez)

7157

Target Species

Human, Mouse, Rat

Form

Liquid

Description

  • This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism
  • p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy
  • p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains
  • It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor
  • Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity
  • Alterations of this gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome
  • Multiple p53 variants due to alternative promoters and multiple alternative splicing have been found
  • These variants encode distinct isoforms, which can regulate p53 transcriptional activity
  • [provided by RefSeq] Sequence: PLSQE

Compare Similar Items

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Abnova Corporation

89-115-974

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Antigen:
TP53

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of TP53.

Formulation:
In TBS, pH 7.2 (BSA, 10% Proclin300)

Gene Alias:
FLJ92943/LFS1/TRP53/p53

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes ∼53 KDa of human TP53. It does not recognize non-phosphorylated peptides.

Content And Storage:
Store at 4°C. For long term storage store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (2-5 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
TP53

Gene Symbols:
TP53

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S15 of human TP53.

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Abnova Corporation

89-115-976

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Antigen:
PAK4

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of PAK4.

Formulation:
In TBS, pH 7.2 (BSA, 10% Proclin300)

Gene Alias:
__

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes PAK4 at a phosphorylation site of Serine 474 (∼68KDa), or serine 602 of PAK5 (∼90KDa) or Serine 560 of PAK6 (∼80 KDa). It does not cross react to other PAK1, PAK2 or PAK3.

Content And Storage:
Store at 4°C. For long term storage store at -20°C or lower.Aliquot to avoid repeated freezing and thawing.

Isotype:
__

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
PAK4

Gene Symbols:
PAK4

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S474 of human PAK4.

Regulatory Status:
RUO

Gene ID (Entrez):
10298

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Abnova Corporation

89-115-977

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Antigen:
ROCK2

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of ROCK2.

Formulation:
In TBS, pH 7.2 (BSA, 10% Proclin300)

Gene Alias:
KIAA0619

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes ∼165 KDa of human ROCK2 at a phosphorylation site of Thr396. It does not react to non-phosphorylated protein.

Content And Storage:
Store at 4°C. For long term storage store at -20°C or lower.Aliquot to avoid repeated freezing and thawing.

Isotype:
__

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (0.5-2 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
ROCK2

Gene Symbols:
ROCK2

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding T396 of human ROCK2.

Regulatory Status:
RUO

Gene ID (Entrez):
9475

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Abnova Corporation

89-115-978

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Antigen:
RHO

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of RHO.

Formulation:
In TBS, pH 7.2 (BSA, 10% Proclin300)

Gene Alias:
CSNBAD1/MGC138309/MGC138311/OPN2/RP4

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes ∼24 KDa of human RHO.

Content And Storage:
Store at 4°C. For long term storage store at -20°C or lower.Aliquot to avoid repeated freezing and thawing.

Isotype:
__

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (2-5 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
RHO

Gene Symbols:
RHO

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S188 of human RHO.

Regulatory Status:
RUO

Gene ID (Entrez):
6010

Target Species:
Human, Mouse, Rat

Form:
Liquid