89-116-248

PSEN1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-116-248-Each-of-1 In Stock ₹ 73,752.72

89-116-248 - Each of 1

₹ 73,752.72

In Stock

Quantity

1

Base Price: ₹ 73,752.72

GST (18%): ₹ 13,275.49

Total Price: ₹ 87,028.21

Antigen

PSEN1

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of PSEN1.

Formulation

In PBS (0.02% sodium azide)

Gene Alias

AD3/FAD/PS1/S182

Host Species

Rabbit

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody has no cross-reactivity to presenilin2.

Content And Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications

Immunohistochemistry (PFA fixed), Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.

Gene

PSEN1

Gene Symbols

PSEN1

Immunogen

A synthetic peptide corresponding to C-terminus 23 amino acids of human PSEN1.

Regulatory Status

RUO

Gene ID (Entrez)

5663

Target Species

Human, Mouse, Rat

Form

Liquid

Description

  • Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP)
  • These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains)
  • Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP
  • Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes
  • Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene, the full-length nature of only some have been determined
  • [provided by RefSeq]

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Abnova Corporation

89-116-248

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Antigen:
PSEN1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of PSEN1.

Formulation:
In PBS (0.02% sodium azide)

Gene Alias:
AD3/FAD/PS1/S182

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody has no cross-reactivity to presenilin2.

Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
PSEN1

Gene Symbols:
PSEN1

Immunogen:
A synthetic peptide corresponding to C-terminus 23 amino acids of human PSEN1.

Regulatory Status:
RUO

Gene ID (Entrez):
5663

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Abnova Corporation

89-116-249

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Antigen:
HAP1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of HAP1.

Formulation:
In PBS (0.02% sodium azide)

Gene Alias:
HAP2/HIP5/HLP/hHLP1

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
HAP1

Gene Symbols:
HAP1

Immunogen:
A synthetic peptide corresponding to internal region 19 amino acids of human HAP1.

Regulatory Status:
RUO

Gene ID (Entrez):
9001

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Abnova Corporation

89-116-250

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Antigen:
CDKN2A

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of CDKN2A.

Formulation:
In PBS (0.02% sodium azide)

Gene Alias:
ARF/CDK4I/CDKN2/CMM2/INK4/INK4a/MLM/MTS1/TP16/p14/p14ARF/p16/p16INK4/p16INK4a/p19

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
CDKN2A

Gene Symbols:
CDKN2A

Immunogen:
A synthetic peptide corresponding to N-terminus 19 amino acids of human CDKN2A.

Regulatory Status:
RUO

Gene ID (Entrez):
1029

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Abnova Corporation

89-116-251

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Antigen:
HUWE1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of HUWE1.

Formulation:
In PBS (0.02% sodium azide)

Gene Alias:
ARF-BP1/HECTH9/HSPC272/Ib772/KIAA0312/LASU1/MULE/UREB1

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
HUWE1

Gene Symbols:
HUWE1

Immunogen:
A synthetic peptide corresponding to C-terminus 19 amino acids of human HUWE1.

Regulatory Status:
RUO

Gene ID (Entrez):
10075

Target Species:
Human, Mouse, Rat

Form:
Liquid