89-116-387

CASP8 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-116-387-Each-of-1 In Stock ₹ 73,752.72

89-116-387 - Each of 1

₹ 73,752.72

In Stock

Quantity

1

Base Price: ₹ 73,752.72

GST (18%): ₹ 13,275.49

Total Price: ₹ 87,028.21

Antigen

CASP8

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of CASP8.

Formulation

In PBS (0.02% sodium azide)

Gene Accession No.

NP_001219

Gene Symbols

CASP8

Immunogen

A synthetic peptide corresponding to C-terminus 16 amino acids of human CASP8.

Regulatory Status

RUO

Gene ID (Entrez)

841

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (0.5 ug/mL) The optimal working dilution should be determined by the end user.

Gene

CASP8

Gene Alias

ALPS2B/CAP4/FLICE/FLJ17672/MACH/MCH5/MGC78473

Host Species

Rabbit

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

Depending on cell lines or tissues used, either full-length or other cleavage products may be observed.

Content And Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • This gene encodes a member of the cysteine-aspartic acid protease (caspase) family
  • Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis
  • Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit
  • Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits
  • This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli
  • The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD
  • This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases
  • Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined
  • [provided by RefSeq

Compare Similar Items

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Img

Abnova Corporation

89-116-387

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Antigen:
CASP8

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of CASP8.

Formulation:
In PBS (0.02% sodium azide)

Gene Accession No.:
NP_001219

Gene Symbols:
CASP8

Immunogen:
A synthetic peptide corresponding to C-terminus 16 amino acids of human CASP8.

Regulatory Status:
RUO

Gene ID (Entrez):
841

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.5 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
CASP8

Gene Alias:
ALPS2B/CAP4/FLICE/FLJ17672/MACH/MCH5/MGC78473

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Depending on cell lines or tissues used, either full-length or other cleavage products may be observed.

Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-116-388

--


Antigen:
CASP8

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of CASP8.

Formulation:
In PBS (0.02% sodium azide)

Gene Accession No.:
NP_001219

Gene Symbols:
CASP8

Immunogen:
A synthetic peptide corresponding to C-terminus of human CASP8.

Regulatory Status:
RUO

Gene ID (Entrez):
841

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.5 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
CASP8

Gene Alias:
ALPS2B/CAP4/FLICE/FLJ17672/MACH/MCH5/MGC78473

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-116-391

--


Antigen:
TSC1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of TSC1.

Formulation:
In PBS (0.02% sodium azide)

Gene Accession No.:
__

Gene Symbols:
TSC1

Immunogen:
A synthetic peptide corresponding to C-terminus 15 amino acids of human TSC1.

Regulatory Status:
RUO

Gene ID (Entrez):
7248

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (2 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
TSC1

Gene Alias:
KIAA0243/LAM/MGC86987/TSC

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-116-392

--


Antigen:
TSC1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of TSC1.

Formulation:
In PBS (0.02% sodium azide)

Gene Accession No.:
__

Gene Symbols:
TSC1

Immunogen:
A synthetic peptide corresponding to internal region 15 amino acids of human TSC1.

Regulatory Status:
RUO

Gene ID (Entrez):
7248

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
TSC1

Gene Alias:
KIAA0243/LAM/MGC86987/TSC

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
TSC1 antibody will recognize both isoforms of TSC1.

Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.