89-116-945

MBD1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-116-945-Each-of-1 In Stock ₹ 67,677.96

89-116-945 - Each of 1

₹ 67,677.96

In Stock

Quantity

1

Base Price: ₹ 67,677.96

GST (18%): ₹ 12,182.033

Total Price: ₹ 79,859.993

Antigen

MBD1

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of MBD1.

Formulation

In PBS (0.05% sodium azide, 0.05% proclin 300)

Gene Alias

CXXC3/PCM1/RFT

Host Species

Rabbit

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ChIP Assay, ELISA

Conjugate

Unconjugated

Dilution

ELISA (1:300-1:1000) ChIP (1.7 ug/ChIP) The optimal working dilution should be determined by the end user.

Gene

MBD1

Gene Symbols

MBD1

Immunogen

A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human MBD1.

Regulatory Status

RUO

Gene ID (Entrez)

4152

Content And Storage

Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development
  • Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD)
  • Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA
  • MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters
  • Five transcript variants of the MBD1 are generated by alternative splicing resulting in protein isoforms that contain one MBD domain, two to three cysteine-rich (CXXC) domains, and some differences in the COOH terminus
  • All five transcript variants repress transcription from methylated promoters; in addition, variants with three CXXC domains also repress unmethylated promoter activity
  • MBD1 and MBD2 map very close to each other on chromosome 18q21
  • [provided by RefSeq

Compare Similar Items

Show Difference

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Abnova Corporation

89-116-945

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Antigen:
MBD1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of MBD1.

Formulation:
In PBS (0.05% sodium azide, 0.05% proclin 300)

Gene Alias:
CXXC3/PCM1/RFT

Host Species:
Rabbit

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ChIP Assay, ELISA

Conjugate:
Unconjugated

Dilution:
ELISA (1:300-1:1000) ChIP (1.7 ug/ChIP) The optimal working dilution should be determined by the end user.

Gene:
MBD1

Gene Symbols:
MBD1

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human MBD1.

Regulatory Status:
RUO

Gene ID (Entrez):
4152

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-116-947

--


Antigen:
DNMT3A

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of DNMT3A.

Formulation:
In PBS (0.05% sodium azide, 0.05% proclin 300)

Gene Alias:
DNMT3A2/M.HsaIIIA

Host Species:
Rabbit

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
ELISA (1:100) Western Blot (1:2000) Immunoprecipitation (2 ug) The optimal working dilution should be determined by the end user.

Gene:
DNMT3A

Gene Symbols:
DNMT3A

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to amino acids 44-58 of human DNMT3A.

Regulatory Status:
RUO

Gene ID (Entrez):
1788

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-116-948

--


Antigen:
DNMT3A

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of DNMT3A.

Formulation:
In PBS (0.05% sodium azide, 0.05% proclin 300)

Gene Alias:
DNMT3A2/M.HsaIIIA

Host Species:
Rabbit

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
ELISA (1:100) Western Blot (1:2500) Immunoprecipitation (2 ug/IP) The optimal working dilution should be determined by the end user.

Gene:
DNMT3A

Gene Symbols:
DNMT3A

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to amino acids 92-106 of human DNMT3A.

Regulatory Status:
RUO

Gene ID (Entrez):
1788

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-116-949

--


Antigen:
DNMT3A

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of DNMT3A.

Formulation:
In PBS (0.05% sodium azide, 0.05% proclin 300)

Gene Alias:
DNMT3A2/M.HsaIIIA

Host Species:
Rabbit

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
ELISA (1:50) Western Blot (1:2000) Immunoprecipitation (2 ug/IP) The optimal working dilution should be determined by the end user.

Gene:
DNMT3A

Gene Symbols:
DNMT3A

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to amino acids 107-121 of human DNMT3A.

Regulatory Status:
RUO

Gene ID (Entrez):
1788

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.