89-117-352

PLAU, Sheep, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-117-352-Each-of-1 In Stock ₹ 83,848.80

89-117-352 - Each of 1

₹ 83,848.80

In Stock

Quantity

1

Base Price: ₹ 83,848.80

GST (18%): ₹ 15,092.784

Total Price: ₹ 98,941.584

Antigen

PLAU

Classification

Polyclonal

Description

Sheep polyclonal antibody raised against native PLAU.

Formulation

In serum

Gene Alias

ATF/UPA/URK/UROKINASE/u-PA

Host Species

Sheep

Quantity

1 mL

Primary or Secondary

Primary

Test Specificity

This antibody reacts only with human u-PA isolated from kidney cell culture tissue. No reactivity with other human proteins. Identity established by double diffusion with u-PA isolated from human kidney tissue and E. coli-derived recombinant u-PA. No cross reactivity with human tissue type plasminogen activator.

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications

ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Immunoprecipitation, Inhibition Assays, Radioimmune Assays (RIA), Western Blot

Conjugate

Unconjugated

Dilution

The optimal working dilution should be determined by the end user.

Gene

PLAU

Gene Symbols

PLAU

Immunogen

Native purified two chain human urinary type high molecular weight PLAU from pooled urine.

Regulatory Status

RUO

Gene ID (Entrez)

5328

Target Species

Human

Form

Liquid

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Description

  • This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation
  • A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding
  • This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen
  • Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain
  • This two-chain derivative is also called HMW-uPA (high molecular weight uPA)
  • HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment
  • LMW-uPA is proteolytically active but does not bind to the uPA receptor
  • Alternatively spliced transcript variants encoding different isoforms have been found for this gene
  • [provided by RefSeq]

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Abnova Corporation

89-117-352

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Antigen:
PLAU

Classification:
Polyclonal

Description:
Sheep polyclonal antibody raised against native PLAU.

Formulation:
In serum

Gene Alias:
ATF/UPA/URK/UROKINASE/u-PA

Host Species:
Sheep

Quantity:
1 mL

Primary or Secondary:
Primary

Test Specificity:
This antibody reacts only with human u-PA isolated from kidney cell culture tissue. No reactivity with other human proteins. Identity established by double diffusion with u-PA isolated from human kidney tissue and E. coli-derived recombinant u-PA. No cross reactivity with human tissue type plasminogen activator.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Immunoprecipitation, Inhibition Assays, Radioimmune Assays (RIA), Western Blot

Conjugate:
Unconjugated

Dilution:
The optimal working dilution should be determined by the end user.

Gene:
PLAU

Gene Symbols:
PLAU

Immunogen:
Native purified two chain human urinary type high molecular weight PLAU from pooled urine.

Regulatory Status:
RUO

Gene ID (Entrez):
5328

Target Species:
Human

Form:
Liquid

Img

Abnova Corporation

89-117-353

--


Antigen:
SLC7A11

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of SLC7A11.

Formulation:
In PBS

Gene Alias:
CCBR1/xCT

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
This antibody reacts with the human and mouse proteins. Other species have not been tested. This is specific to XCT. By Western blot a band at ∼55 KDa is seen. Immunoprecipitation is not recommended.

Content And Storage:
Store at 4°C. Do not freeze.

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Biotin

Dilution:
Western Blot (1:1000) The optimal working dilution should be determined by the end user.

Gene:
SLC7A11

Gene Symbols:
SLC7A11

Immunogen:
A synthetic peptide corresponding to amino acids 1-50 of human SLC7A11.

Regulatory Status:
RUO

Gene ID (Entrez):
23657

Target Species:
Human, Mouse

Form:
Liquid

Img

Abnova Corporation

89-117-354

--


Antigen:
SLC7A11

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of SLC7A11.

Formulation:
In PBS

Gene Alias:
CCBR1/xCT

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
This antibody reacts with the human and mouse proteins. Other species have not been tested. This is specific to XCT. By Western blot a band at ∼55 KDa is seen. Immunoprecipitation is not recommended.

Content And Storage:
Store at 4°C. Do not freeze.

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
HRP

Dilution:
Western Blot (1:1000) The optimal working dilution should be determined by the end user.

Gene:
SLC7A11

Gene Symbols:
SLC7A11

Immunogen:
A synthetic peptide corresponding to amino acids 1-50 of human SLC7A11.

Regulatory Status:
RUO

Gene ID (Entrez):
23657

Target Species:
Human, Mouse

Form:
Liquid

Img

Abnova Corporation

89-117-357

--


Antigen:
SLC7A11

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of Slc7a11.

Formulation:
In PBS

Gene Alias:
9930009M05Rik/AI451155/sut/xCT

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
This antibody reacts with the human protein. It does not react with murine stomach tissue in Western blot. Other species have not been tested. This is specific to XCT. By Western blot a band at ∼55 KDa is seen. No other applications have been tested. Recommended Starting Dilutions: Western Blot: 1 ug/ml (ECL) Immunoprecipitation: Not tested Immunohisto/cytochemistry: Not tested *Optimal working dilutions should be determined by the investigator.

Content And Storage:
Store at 4°C. Do not freeze.

Applications:
Western Blot

Conjugate:
HRP

Dilution:
The optimal working dilution should be determined by the end user.

Gene:
Slc7a11

Gene Symbols:
Slc7a11

Immunogen:
A synthetic peptide corresponding to amino acids 1-50 of mouse Slc7a11.

Regulatory Status:
RUO

Gene ID (Entrez):
26570

Target Species:
Mouse

Form:
Liquid