89-117-585

CDKN2A Rabbit anti-Human, DyLight 488, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-117-585-Each-of-1 In Stock ₹ 84,019.92

89-117-585 - Each of 1

₹ 84,019.92

In Stock

Quantity

1

Base Price: ₹ 84,019.92

GST (18%): ₹ 15,123.586

Total Price: ₹ 99,143.506

Antigen

CDKN2A

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of CDKN2A.

Formulation

In 50mM sodium borate

Gene Accession No.

Q8N726

Gene Symbols

CDKN2A

Immunogen

A synthetic peptide corresponding to amino acids 50-150 of human CDKN2A.

Regulatory Status

RUO

Gene ID (Entrez)

1029

Target Species

Human

Form

Liquid

Applications

Immunofluorescence, Western Blot

Conjugate

DyLight 488

Dilution

Immunofluorescence (1:100) Western Blot (2 ug/mL) The optimal working dilution should be determined by the end user.

Gene

CDKN2A

Gene Alias

ARF/CDK4I/CDKN2/CMM2/INK4/INK4a/MLM/MTS1/TP16/p14/p14ARF/p16/p16INK4/p16INK4a/p19

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Test Specificity

This antibody reacts with human p14 ARF. Other species untested. This is specific to p14ARF. This antibody may be used for Western blotting, where a band is seen at where a band is seen at ∼16 KDa, representing p14ARF (p14ARF tends to run slightly higher than the theoretical MW of 14 KDa). Additional faint bands may be seen at ∼32 and 47 KDa.

Content And Storage

Store at 4°C. Do not freeze.

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Description

  • This gene generates several transcript variants which differ in their first exons
  • At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase
  • The remaining transcript includes an alternate first exon located 20kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants
  • This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, MDM1, a protein responsible for the degradation of p53
  • In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control
  • This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene
  • [provided by RefSeq

Compare Similar Items

Show Difference

Img

Abnova Corporation

89-117-585

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Antigen:
CDKN2A

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of CDKN2A.

Formulation:
In 50mM sodium borate

Gene Accession No.:
Q8N726

Gene Symbols:
CDKN2A

Immunogen:
A synthetic peptide corresponding to amino acids 50-150 of human CDKN2A.

Regulatory Status:
RUO

Gene ID (Entrez):
1029

Target Species:
Human

Form:
Liquid

Applications:
Immunofluorescence, Western Blot

Conjugate:
DyLight 488

Dilution:
Immunofluorescence (1:100) Western Blot (2 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
CDKN2A

Gene Alias:
ARF/CDK4I/CDKN2/CMM2/INK4/INK4a/MLM/MTS1/TP16/p14/p14ARF/p16/p16INK4/p16INK4a/p19

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
This antibody reacts with human p14 ARF. Other species untested. This is specific to p14ARF. This antibody may be used for Western blotting, where a band is seen at where a band is seen at ∼16 KDa, representing p14ARF (p14ARF tends to run slightly higher than the theoretical MW of 14 KDa). Additional faint bands may be seen at ∼32 and 47 KDa.

Content And Storage:
Store at 4°C. Do not freeze.

Img

Abnova Corporation

89-117-586

--


Antigen:
CDKN2A

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of CDKN2A.

Formulation:
In PBS

Gene Accession No.:
Q8N726

Gene Symbols:
CDKN2A

Immunogen:
A synthetic peptide corresponding to amino acids 100-200 of human CDKN2A.

Regulatory Status:
RUO

Gene ID (Entrez):
1029

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Conjugate:
Biotin

Dilution:
Western Blot (2 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
CDKN2A

Gene Alias:
ARF/CDK4I/CDKN2/CMM2/INK4/INK4a/MLM/MTS1/TP16/p14/p14ARF/p16/p16INK4/p16INK4a/p19

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
This antibody reacts with human p14ARF. Other species have not been tested. This is specific to p14ARF. This antibody may be used for Western blotting, where a band is seen at ∼16 KDa, representing p14ARF (p14ARF tends to run slightly higher than the theoretical MW of 14 KDa). Additional non-specific bands may be seen at ∼25 and 47 KDa.

Content And Storage:
Store at 4°C. Do not freeze.

Img

Abnova Corporation

89-117-587

--


Antigen:
CDKN2A

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of CDKN2A.

Formulation:
In PBS

Gene Accession No.:
Q8N726

Gene Symbols:
CDKN2A

Immunogen:
A synthetic peptide corresponding to amino acids 50-150 of human CDKN2A.

Regulatory Status:
RUO

Gene ID (Entrez):
1029

Target Species:
Human

Form:
Liquid

Applications:
Immunofluorescence, Western Blot

Conjugate:
Biotin

Dilution:
Immunofluorescence (1:100) Western Blot (2 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
CDKN2A

Gene Alias:
ARF/CDK4I/CDKN2/CMM2/INK4/INK4a/MLM/MTS1/TP16/p14/p14ARF/p16/p16INK4/p16INK4a/p19

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
This antibody reacts with human p14 ARF. Other species untested. This is specific to p14ARF. This antibody may be used for Western blotting, where a band is seen at where a band is seen at ∼16 KDa, representing p14ARF (p14ARF tends to run slightly higher than the theoretical MW of 14 KDa). Additional faint bands may be seen at ∼32 and 47 KDa.

Content And Storage:
Store at 4°C. Do not freeze.

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Abnova Corporation

89-117-591

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Antigen:
ALB

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against native ALB.

Formulation:
In 20mM sodium phosphate buffer, 140mM NaCl, pH 7.3 (0.05% sodium azide)

Gene Accession No.:
__

Gene Symbols:
ALB

Immunogen:
Native purified bovine ALB.

Regulatory Status:
RUO

Gene ID (Entrez):
280717

Target Species:
Bovine

Form:
Liquid

Applications:
ELISA, Immunodiffusion, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Dilution:
The optimal working dilution should be determined by the end user.

Gene:
ALB

Gene Alias:
MGC179277

Host Species:
Rabbit

Quantity:
2 mg

Primary or Secondary:
Primary

Test Specificity:
It shows reactivity to bovine albumin; cross-reactivity to other species may exist. Antibody activity to other serum proteins is not present.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.