89-117-954
MLL (phospho S516), Rabbit anti-Human, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-117-954-Each-of-1 | In Stock | ₹ 67,763.52 |
89-117-954 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 67,763.52
GST (18%): ₹ 12,197.434
Total Price: ₹ 79,960.954
Antigen
MLL
Classification
Polyclonal
Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of MLL.
Formulation
In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Gene Alias
ALL-1/CXXC7/FLJ11783/HRX/HTRX1/KMT2A/MLL/GAS7/MLL1A/TET1-MLL/TRX1
Host Species
Rabbit
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Dilution
ELISA (1:2000-1:5000) Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
Gene
MLL
Gene Symbols
MLL
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding S516 of human MLL.
Regulatory Status
RUO
Gene ID (Entrez)
4297
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Related Products
Description
- The MLL gene encodes a DNA-binding protein that methylates histone H3 (see MIM 601128) lys4 (H3K4) and positively regulates expression of target genes, including multiple HOX genes (see MIM 142980)
- MLL is a frequent target for recurrent translocations in acute leukemias that may be characterized as acute myeloid leukemia (AML; MIM 601626), acute lymphoblastic leukemia (ALL), or mixed lineage (biphenotypic) leukemia (MLL)
- Leukemias with translocations involving MLL possess unique clinical and biologic characteristics and are often associated with poor prognosis
- MLL rearrangements are found in more than 70% of infant leukemias, whether the immunophenotype is more consistent with ALL or AML6, but are less frequent in leukemias from older children
- MLL translocations are also found in approximately 10% of AMLs in adults, as well as in therapy-related leukemias, most often characterized as AML, that develop in patients previously treated with topoisomerase II inhibitors for other malignancies
- More than 50 different MLL fusion partners have been identified
- Leukemogenic MLL translocations encode MLL fusion proteins that have lost H3K4 methyltransferase activity
- A key feature of MLL fusion proteins is their ability to efficiently transform hematopoietic cells into leukemia stem cells (Krivtsov and Armstrong, 2007 [PubMed 17957188]).[supplied by OMIM
Compare Similar Items
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Antigen: MLL
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of MLL.
Formulation: In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Gene Alias: ALL-1/CXXC7/FLJ11783/HRX/HTRX1/KMT2A/MLL/GAS7/MLL1A/TET1-MLL/TRX1
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Dilution: ELISA (1:2000-1:5000) Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
Gene: MLL
Gene Symbols: MLL
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S516 of human MLL.
Regulatory Status: RUO
Gene ID (Entrez): 4297
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen:
MLL
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of MLL.
Formulation:
In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Gene Alias:
ALL-1/CXXC7/FLJ11783/HRX/HTRX1/KMT2A/MLL/GAS7/MLL1A/TET1-MLL/TRX1
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Dilution:
ELISA (1:2000-1:5000) Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
Gene:
MLL
Gene Symbols:
MLL
Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S516 of human MLL.
Regulatory Status:
RUO
Gene ID (Entrez):
4297
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen: IKBKB
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of IKBKB.
Formulation: In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Gene Alias: FLJ40509/IKK-beta/IKK2/IKKB/MGC131801/NFKBIKB
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Dilution: ELISA (1:2000-1:5000) Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
Gene: IKBKB
Gene Symbols: IKBKB
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S740 of human IKBKB.
Regulatory Status: RUO
Gene ID (Entrez): 3551
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen:
IKBKB
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of IKBKB.
Formulation:
In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Gene Alias:
FLJ40509/IKK-beta/IKK2/IKKB/MGC131801/NFKBIKB
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Dilution:
ELISA (1:2000-1:5000) Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
Gene:
IKBKB
Gene Symbols:
IKBKB
Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S740 of human IKBKB.
Regulatory Status:
RUO
Gene ID (Entrez):
3551
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen: MAP4
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of MAP4.
Formulation: In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Gene Alias: DKFZp779A1753/MGC8617
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Dilution: ELISA (1:2000-1:5000) Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
Gene: MAP4
Gene Symbols: MAP4
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S1073 of human MAP4.
Regulatory Status: RUO
Gene ID (Entrez): 4134
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen:
MAP4
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of MAP4.
Formulation:
In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Gene Alias:
DKFZp779A1753/MGC8617
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Dilution:
ELISA (1:2000-1:5000) Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
Gene:
MAP4
Gene Symbols:
MAP4
Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S1073 of human MAP4.
Regulatory Status:
RUO
Gene ID (Entrez):
4134
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen: MAPK11
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of MAPK11.
Formulation: In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Gene Alias: P38B/P38BETA2/PRKM11/SAPK2/SAPK2B/p38-2/p38Beta
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Liquid
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Dilution: ELISA (1:2000-1:5000) Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
Gene: MAPK11
Gene Symbols: MAPK11
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding T180/T182 of human MAPK11.
Regulatory Status: RUO
Gene ID (Entrez): 5600
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen:
MAPK11
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of MAPK11.
Formulation:
In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Gene Alias:
P38B/P38BETA2/PRKM11/SAPK2/SAPK2B/p38-2/p38Beta
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Liquid
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Dilution:
ELISA (1:2000-1:5000) Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
Gene:
MAPK11
Gene Symbols:
MAPK11
Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding T180/T182 of human MAPK11.
Regulatory Status:
RUO
Gene ID (Entrez):
5600
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.