89-118-754

TP53 (phospho S20), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-118-754-Each-of-1 In Stock ₹ 54,929.52

89-118-754 - Each of 1

₹ 54,929.52

In Stock

Quantity

1

Base Price: ₹ 54,929.52

GST (18%): ₹ 9,887.314

Total Price: ₹ 64,816.834

Antigen

TP53

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of TP53.

Formulation

In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)

Gene Alias

FLJ92943/LFS1/TRP53/p53

Host Species

Rabbit

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody detects endogenous levels of TP53 only when phosphorylated at serine 20.

Content And Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications

ELISA, Immunohistochemistry (PFA fixed), Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:4000) The optimal working dilution should be determined by the end user.

Gene

TP53

Gene Symbols

TP53

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding S20 of human TP53.

Regulatory Status

RUO

Gene ID (Entrez)

7157

Target Species

Human, Mouse

Form

Liquid

Description

  • This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism
  • p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy
  • p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains
  • It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor
  • Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity
  • Alterations of this gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome
  • Multiple p53 variants due to alternative promoters and multiple alternative splicing have been found
  • These variants encode distinct isoforms, which can regulate p53 transcriptional activity
  • [provided by RefSeq]

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Abnova Corporation

89-118-754

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Antigen:
TP53

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of TP53.

Formulation:
In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)

Gene Alias:
FLJ92943/LFS1/TRP53/p53

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody detects endogenous levels of TP53 only when phosphorylated at serine 20.

Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:4000) The optimal working dilution should be determined by the end user.

Gene:
TP53

Gene Symbols:
TP53

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S20 of human TP53.

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Target Species:
Human, Mouse

Form:
Liquid

Img

Abnova Corporation

89-118-755

--


Antigen:
TP53

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of TP53.

Formulation:
In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)

Gene Alias:
FLJ92943/LFS1/TRP53/p53

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody detects endogenous levels of TP53 only when phosphorylated at serine 37.

Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:4000) The optimal working dilution should be determined by the end user.

Gene:
TP53

Gene Symbols:
TP53

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S37 of human TP53.

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Target Species:
Human

Form:
Liquid

Img

Abnova Corporation

89-118-756

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Antigen:
PDGFRB

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of PDGFRB.

Formulation:
In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)

Gene Alias:
CD140B/JTK12/PDGF-R-beta/PDGFR/PDGFR1

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody detects endogenous levels of PDGFRB only when phosphorylated at tyrosine 751.

Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:4000) The optimal working dilution should be determined by the end user.

Gene:
PDGFRB

Gene Symbols:
PDGFRB

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding Y751 of human PDGFRB.

Regulatory Status:
RUO

Gene ID (Entrez):
5159

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Abnova Corporation

89-118-757

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Antigen:
STK11

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of STK11.

Formulation:
In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)

Gene Alias:
LKB1/PJS

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody detects endogenous levels of STK11 only when phosphorylated at serine 334.

Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:4000) The optimal working dilution should be determined by the end user.

Gene:
STK11

Gene Symbols:
STK11

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S334 of human STK11.

Regulatory Status:
RUO

Gene ID (Entrez):
6794

Target Species:
Human, Mouse

Form:
Liquid