89-118-800
CHEK2 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-118-800-Each-of-1 | In Stock | ₹ 51,079.32 |
89-118-800 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,079.32
GST (18%): ₹ 9,194.278
Total Price: ₹ 60,273.598
Antigen
CHEK2
Classification
Polyclonal
Description
Rabbit polyclonal antibody raised against synthetic peptide of CHEK2.
Formulation
In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)
Gene Accession No.
O96017
Gene Symbols
CHEK2
Immunogen
A synthetic peptide corresponding to residues surrounding T387 of human CHEK2.
Regulatory Status
RUO
Gene ID (Entrez)
11200
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Conjugate
Unconjugated
Dilution
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:20000) The optimal working dilution should be determined by the end user.
Gene
CHEK2
Gene Alias
CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species
Rabbit
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
This antibody detects endogenous levels of total CHEK2 protein.
Content And Storage
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Description
- In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators
- The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor
- It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage
- When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1
- In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage
- Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53
- Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors
- This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases
- Three transcript variants encoding different isoforms have been found for this gene
- [provided by RefSeq
Compare Similar Items
Show Difference
Antigen: CHEK2
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against synthetic peptide of CHEK2.
Formulation: In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)
Gene Accession No.: O96017
Gene Symbols: CHEK2
Immunogen: A synthetic peptide corresponding to residues surrounding T387 of human CHEK2.
Regulatory Status: RUO
Gene ID (Entrez): 11200
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
Conjugate: Unconjugated
Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:20000) The optimal working dilution should be determined by the end user.
Gene: CHEK2
Gene Alias: CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This antibody detects endogenous levels of total CHEK2 protein.
Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen:
CHEK2
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against synthetic peptide of CHEK2.
Formulation:
In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)
Gene Accession No.:
O96017
Gene Symbols:
CHEK2
Immunogen:
A synthetic peptide corresponding to residues surrounding T387 of human CHEK2.
Regulatory Status:
RUO
Gene ID (Entrez):
11200
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Conjugate:
Unconjugated
Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:20000) The optimal working dilution should be determined by the end user.
Gene:
CHEK2
Gene Alias:
CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody detects endogenous levels of total CHEK2 protein.
Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen: CRKL
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against synthetic peptide of CRKL.
Formulation: In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)
Gene Accession No.: P46109
Gene Symbols: CRKL
Immunogen: A synthetic peptide corresponding to residues surrounding Y207 of human CRKL.
Regulatory Status: RUO
Gene ID (Entrez): 1399
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
Conjugate: Unconjugated
Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:20000) The optimal working dilution should be determined by the end user.
Gene: CRKL
Gene Alias: __
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This antibody detects endogenous levels of total CRKL protein.
Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen:
CRKL
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against synthetic peptide of CRKL.
Formulation:
In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)
Gene Accession No.:
P46109
Gene Symbols:
CRKL
Immunogen:
A synthetic peptide corresponding to residues surrounding Y207 of human CRKL.
Regulatory Status:
RUO
Gene ID (Entrez):
1399
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Conjugate:
Unconjugated
Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:20000) The optimal working dilution should be determined by the end user.
Gene:
CRKL
Gene Alias:
__
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody detects endogenous levels of total CRKL protein.
Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen: FGFR1
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against synthetic peptide of FGFR1.
Formulation: In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)
Gene Accession No.: P11362
Gene Symbols: FGFR1
Immunogen: A synthetic peptide corresponding to residues surrounding Y154 of human FGFR1.
Regulatory Status: RUO
Gene ID (Entrez): 2260
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
Conjugate: Unconjugated
Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:20000) The optimal working dilution should be determined by the end user.
Gene: FGFR1
Gene Alias: BFGFR/CD331/CEK/FGFBR/FLG/FLJ99988/FLT2/HBGFR/KAL2/N-SAM
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This antibody detects endogenous levels of total FGFR1 protein.
Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen:
FGFR1
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against synthetic peptide of FGFR1.
Formulation:
In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)
Gene Accession No.:
P11362
Gene Symbols:
FGFR1
Immunogen:
A synthetic peptide corresponding to residues surrounding Y154 of human FGFR1.
Regulatory Status:
RUO
Gene ID (Entrez):
2260
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Conjugate:
Unconjugated
Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:20000) The optimal working dilution should be determined by the end user.
Gene:
FGFR1
Gene Alias:
BFGFR/CD331/CEK/FGFBR/FLG/FLJ99988/FLT2/HBGFR/KAL2/N-SAM
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody detects endogenous levels of total FGFR1 protein.
Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen: FLT3
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against synthetic peptide of FLT3.
Formulation: In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)
Gene Accession No.: P36888
Gene Symbols: FLT3
Immunogen: A synthetic peptide corresponding to residues surrounding Y591 of human FLT3.
Regulatory Status: RUO
Gene ID (Entrez): 2322
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
Conjugate: Unconjugated
Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:20000) The optimal working dilution should be determined by the end user.
Gene: FLT3
Gene Alias: CD135/FLK2/STK1
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This antibody detects endogenous levels of total FLT3 protein.
Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen:
FLT3
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against synthetic peptide of FLT3.
Formulation:
In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)
Gene Accession No.:
P36888
Gene Symbols:
FLT3
Immunogen:
A synthetic peptide corresponding to residues surrounding Y591 of human FLT3.
Regulatory Status:
RUO
Gene ID (Entrez):
2322
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Conjugate:
Unconjugated
Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:20000) The optimal working dilution should be determined by the end user.
Gene:
FLT3
Gene Alias:
CD135/FLK2/STK1
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody detects endogenous levels of total FLT3 protein.
Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.