89-118-809

ALK (phospho Y1586), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-118-809-Each-of-1 In Stock ₹ 54,929.52

89-118-809 - Each of 1

₹ 54,929.52

In Stock

Quantity

1

Base Price: ₹ 54,929.52

GST (18%): ₹ 9,887.314

Total Price: ₹ 64,816.834

Antigen

ALK

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of ALK.

Formulation

In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)

Gene Accession No.

Q9UM73

Gene Symbols

ALK

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding Y1586 of human ALK.

Regulatory Status

RUO

Gene ID (Entrez)

238

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (PFA fixed), Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:4000) The optimal working dilution should be determined by the end user.

Gene

ALK

Gene Alias

CD246/Ki-1/TFG/ALK

Host Species

Rabbit

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody detects endogenous levels of ALK only when phosphorylated at tyrosine 1586.

Content And Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • The 2;5 chromosomal translocation is frequently associated with anaplastic large cell lymphomas (ALCLs)
  • The translocation creates a fusion gene consisting of the ALK (anaplastic lymphoma kinase) gene and the nucleophosmin (NPM) gene: the 3' half of ALK, derived from chromosome 2, is fused to the 5' portion of NPM from chromosome 5
  • A recent study shows that the product of the NPM-ALK fusion gene is oncogenic
  • The deduced amino acid sequences reveal that ALK is a novel receptor protein-tyrosine kinase having a putative transmembrane domain and an extracellular domain
  • These sequences are absent in the product of the transforming NPM-ALK gene
  • ALK shows the greatest sequence similarity to LTK (leukocyte tyrosine kinase)
  • ALK plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system
  • [provided by RefSeq]

Compare Similar Items

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Img

Abnova Corporation

89-118-809

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Antigen:
ALK

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of ALK.

Formulation:
In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)

Gene Accession No.:
Q9UM73

Gene Symbols:
ALK

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding Y1586 of human ALK.

Regulatory Status:
RUO

Gene ID (Entrez):
238

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:4000) The optimal working dilution should be determined by the end user.

Gene:
ALK

Gene Alias:
CD246/Ki-1/TFG/ALK

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody detects endogenous levels of ALK only when phosphorylated at tyrosine 1586.

Content And Storage:
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-118-810

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Antigen:
UBE2S

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of UBE2S.

Formulation:
In PBS (0.09% sodium azide)

Gene Accession No.:
__

Gene Symbols:
UBE2S

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human UBE2S.

Regulatory Status:
RUO

Gene ID (Entrez):
27338

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.

Gene:
UBE2S

Gene Alias:
E2-EPF/E2EPF/EPF5

Host Species:
Rabbit

Quantity:
400 μL

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-118-811

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Antigen:
MYST3

Classification:
Polyclonal

Description:
Goat polyclonal antibody raised against synthetic peptide of MYST3.

Formulation:
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)

Gene Accession No.:
__

Gene Symbols:
MYST3

Immunogen:
A synthetic peptide corresponding to human MYST3.

Regulatory Status:
RUO

Gene ID (Entrez):
7994

Target Species:
Human

Form:
Liquid

Applications:
ELISA

Conjugate:
Unconjugated

Dilution:
ELISA (1:16000) The optimal working dilution should be determined by the end user.

Gene:
MYST3

Gene Alias:
KAT6A/MGC167033/MOZ/RUNXBP2/ZNF220

Host Species:
Goat

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-118-812

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Antigen:
HTR7

Classification:
Polyclonal

Description:
Goat polyclonal antibody raised against synthetic peptide of HTR7.

Formulation:
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)

Gene Accession No.:
__

Gene Symbols:
HTR7

Immunogen:
A synthetic peptide corresponding to human HTR7.

Regulatory Status:
RUO

Gene ID (Entrez):
3363

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Dilution:
ELISA (1:16000) Western Blot (1-3 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
HTR7

Gene Alias:
5-HT7

Host Species:
Goat

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.