89-119-667

PPP1R1B Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-119-667-Each-of-1 In Stock ₹ 53,731.68

89-119-667 - Each of 1

₹ 53,731.68

In Stock

Quantity

1

Base Price: ₹ 53,731.68

GST (18%): ₹ 9,671.702

Total Price: ₹ 63,403.382

Antigen

PPP1R1B

Classification

Polyclonal

Conjugate

Unconjugated

Dilution

Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:40000) The optimal working dilution should be determined by the end user.

Gene

PPP1R1B

Gene Symbols

PPP1R1B

Immunogen

A synthetic peptide corresponding to human PPP1R1B.

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody is specific to PPP1R1B.

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications

ELISA, Immunohistochemistry (PFA fixed), Western Blot

Concentration

1 mg/mL

Description

Rabbit polyclonal antibody raised against synthetic peptide of PPP1R1B.

Formulation

In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias

DARPP-32/DARPP32/FLJ20940

Host Species

Rabbit

Purification Method

Affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

84152

Target Species

Human, Mouse, Rat

Form

Liquid

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Description

  • Midbrain dopaminergic neurons play a critical role in multiple brain functions, and abnormal signaling through dopaminergic pathways has been implicated in several major neurologic and psychiatric disorders
  • One well-studied target for the actions of dopamine is DARPP32
  • In the densely dopamine- and glutamate-innervated rat caudate-putamen, DARPP32 is expressed in medium-sized spiny neurons (Ouimet and Greengard, 1990 [PubMed 2191086]) that also express dopamine D1 receptors (Walaas and Greengard, 1984 [PubMed 6319627])
  • The function of DARPP32 seems to be regulated by receptor stimulation
  • Both dopaminergic and glutamatergic (NMDA) receptor stimulation regulate the extent of DARPP32 phosphorylation, but in opposite directions (Halpain et al., 1990 [PubMed 2153935])
  • Dopamine D1 receptor stimulation enhances cAMP formation, resulting in the phosphorylation of DARPP32 (Walaas and Greengard, 1984 [PubMed 6319627]); phosphorylated DARPP32 is a potent protein phosphatase-1 (see MIM 176875) inhibitor (Hemmings et al., 1984 [PubMed 6087160])
  • NMDA receptor stimulation elevates intracellular calcium, which leads to activation of calcineurin and dephosphorylation of phospho-DARPP32, thereby reducing the phosphatase-1 inhibitory activity of DARPP32 (Halpain et al., 1990 [PubMed 2153935]).[supplied by OMIM

Compare Similar Items

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Img

Abnova Corporation

89-119-667

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Antigen:
PPP1R1B

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:40000) The optimal working dilution should be determined by the end user.

Gene:
PPP1R1B

Gene Symbols:
PPP1R1B

Immunogen:
A synthetic peptide corresponding to human PPP1R1B.

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody is specific to PPP1R1B.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1 mg/mL

Description:
Rabbit polyclonal antibody raised against synthetic peptide of PPP1R1B.

Formulation:
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias:
DARPP-32/DARPP32/FLJ20940

Host Species:
Rabbit

Purification Method:
Affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
84152

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Abnova Corporation

89-119-669

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Antigen:
EGFR

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1:300-1:1000) Immunohistochemistry (1:50-1:100) Immunofluorescence (1:500-1:1000) ELISA (1:40000) The optimal working dilution should be determined by the end user.

Gene:
EGFR

Gene Symbols:
EGFR

Immunogen:
A synthetic peptide corresponding to human EGFR.

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody is specific to EGFR.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1 mg/mL

Description:
Rabbit polyclonal antibody raised against synthetic peptide of EGFR.

Formulation:
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias:
ERBB/ERBB1/HER1/PIG61/mENA

Host Species:
Rabbit

Purification Method:
Affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
1956

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Abnova Corporation

89-119-671

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Antigen:
HSP90AB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) Immunofluorescence (1:500-1:1000) ELISA (1:40000) The optimal working dilution should be determined by the end user.

Gene:
HSP90AB1

Gene Symbols:
HSP90AB1

Immunogen:
A synthetic peptide corresponding to human HSP90AB1.

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody is specific to HSP90AB1.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Description:
Rabbit polyclonal antibody raised against synthetic peptide of HSP90AB1.

Formulation:
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias:
D6S182/FLJ26984/HSP90-BETA/HSP90B/HSPC2/HSPCB

Host Species:
Rabbit

Purification Method:
Affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
3326

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Abnova Corporation

89-119-672

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Antigen:
NFKBIE

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) Immunofluorescence (1:500-1:1000) ELISA (1:40000) The optimal working dilution should be determined by the end user.

Gene:
NFKBIE

Gene Symbols:
NFKBIE

Immunogen:
A synthetic peptide corresponding to human NFKBIE.

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody is specific to NFKBIE.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1 mg/mL

Description:
Rabbit polyclonal antibody raised against synthetic peptide of NFKBIE.

Formulation:
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias:
IKBE

Host Species:
Rabbit

Purification Method:
Affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
4794

Target Species:
Human, Mouse, Rat

Form:
Liquid