89-119-720
CHEK2 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-119-720-Each-of-1 | In Stock | ₹ 53,731.68 |
89-119-720 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,731.68
GST (18%): ₹ 9,671.702
Total Price: ₹ 63,403.382
Antigen
CHEK2
Classification
Polyclonal
Conjugate
Unconjugated
Dilution
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:5000) The optimal working dilution should be determined by the end user.
Gene
CHEK2
Gene Alias
CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species
Rabbit
Purification Method
Affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
11200
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Concentration
1 mg/mL
Description
Rabbit polyclonal antibody raised against synthetic peptide of CHEK2.
Formulation
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.
O96017
Gene Symbols
CHEK2
Immunogen
A synthetic peptide corresponding to human CHEK2.
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
This antibody is specific to CHEK2.
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Description
- In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators
- The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor
- It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage
- When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1
- In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage
- Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53
- Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors
- This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases
- Three transcript variants encoding different isoforms have been found for this gene
- [provided by RefSeq
Compare Similar Items
Show Difference
Antigen: CHEK2
Classification: Polyclonal
Conjugate: Unconjugated
Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:5000) The optimal working dilution should be determined by the end user.
Gene: CHEK2
Gene Alias: CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species: Rabbit
Purification Method: Affinity purification
Regulatory Status: RUO
Gene ID (Entrez): 11200
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
Concentration: 1 mg/mL
Description: Rabbit polyclonal antibody raised against synthetic peptide of CHEK2.
Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.: O96017
Gene Symbols: CHEK2
Immunogen: A synthetic peptide corresponding to human CHEK2.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This antibody is specific to CHEK2.
Content And Storage: Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen:
CHEK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:5000) The optimal working dilution should be determined by the end user.
Gene:
CHEK2
Gene Alias:
CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species:
Rabbit
Purification Method:
Affinity purification
Regulatory Status:
RUO
Gene ID (Entrez):
11200
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Concentration:
1 mg/mL
Description:
Rabbit polyclonal antibody raised against synthetic peptide of CHEK2.
Formulation:
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.:
O96017
Gene Symbols:
CHEK2
Immunogen:
A synthetic peptide corresponding to human CHEK2.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody is specific to CHEK2.
Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen: CCND1
Classification: Polyclonal
Conjugate: Unconjugated
Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:40000) The optimal working dilution should be determined by the end user.
Gene: CCND1
Gene Alias: BCL1/D11S287E/PRAD1/U21B31
Host Species: Rabbit
Purification Method: Affinity purification
Regulatory Status: RUO
Gene ID (Entrez): 595
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
Concentration: 1 mg/mL
Description: Rabbit polyclonal antibody raised against synthetic peptide of CCND1.
Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.: P24385
Gene Symbols: CCND1
Immunogen: A synthetic peptide corresponding to human CCND1.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This antibody is specific to CCND1.
Content And Storage: Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen:
CCND1
Classification:
Polyclonal
Conjugate:
Unconjugated
Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:40000) The optimal working dilution should be determined by the end user.
Gene:
CCND1
Gene Alias:
BCL1/D11S287E/PRAD1/U21B31
Host Species:
Rabbit
Purification Method:
Affinity purification
Regulatory Status:
RUO
Gene ID (Entrez):
595
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Concentration:
1 mg/mL
Description:
Rabbit polyclonal antibody raised against synthetic peptide of CCND1.
Formulation:
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.:
P24385
Gene Symbols:
CCND1
Immunogen:
A synthetic peptide corresponding to human CCND1.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody is specific to CCND1.
Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen: PRKDC
Classification: Polyclonal
Conjugate: Unconjugated
Dilution: Immunohistochemistry (1:50-1:100) ELISA (1:40000) The optimal working dilution should be determined by the end user.
Gene: PRKDC
Gene Alias: DNA-PKcs/DNAPK/DNPK1/HYRC/HYRC1/XRCC7/p350
Host Species: Rabbit
Purification Method: Affinity purification
Regulatory Status: RUO
Gene ID (Entrez): 5591
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry (PFA fixed)
Concentration: 1 mg/mL
Description: Rabbit polyclonal antibody raised against synthetic peptide of PRKDC.
Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.: __
Gene Symbols: PRKDC
Immunogen: A synthetic peptide corresponding to human PRKDC.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This antibody is specific to PRKDC.
Content And Storage: Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen:
PRKDC
Classification:
Polyclonal
Conjugate:
Unconjugated
Dilution:
Immunohistochemistry (1:50-1:100) ELISA (1:40000) The optimal working dilution should be determined by the end user.
Gene:
PRKDC
Gene Alias:
DNA-PKcs/DNAPK/DNPK1/HYRC/HYRC1/XRCC7/p350
Host Species:
Rabbit
Purification Method:
Affinity purification
Regulatory Status:
RUO
Gene ID (Entrez):
5591
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (PFA fixed)
Concentration:
1 mg/mL
Description:
Rabbit polyclonal antibody raised against synthetic peptide of PRKDC.
Formulation:
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.:
__
Gene Symbols:
PRKDC
Immunogen:
A synthetic peptide corresponding to human PRKDC.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody is specific to PRKDC.
Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen: NR3C1
Classification: Polyclonal
Conjugate: Unconjugated
Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:10000) The optimal working dilution should be determined by the end user.
Gene: NR3C1
Gene Alias: GCCR/GCR/GR/GRL
Host Species: Rabbit
Purification Method: Affinity purification
Regulatory Status: RUO
Gene ID (Entrez): 2908
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
Concentration: 1 mg/mL
Description: Rabbit polyclonal antibody raised against synthetic peptide of NR3C1.
Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.: __
Gene Symbols: NR3C1
Immunogen: A synthetic peptide corresponding to human NR3C1.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This antibody is specific to NR3C1.
Content And Storage: Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Antigen:
NR3C1
Classification:
Polyclonal
Conjugate:
Unconjugated
Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:10000) The optimal working dilution should be determined by the end user.
Gene:
NR3C1
Gene Alias:
GCCR/GCR/GR/GRL
Host Species:
Rabbit
Purification Method:
Affinity purification
Regulatory Status:
RUO
Gene ID (Entrez):
2908
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Concentration:
1 mg/mL
Description:
Rabbit polyclonal antibody raised against synthetic peptide of NR3C1.
Formulation:
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.:
__
Gene Symbols:
NR3C1
Immunogen:
A synthetic peptide corresponding to human NR3C1.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody is specific to NR3C1.
Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.