89-126-444

TP53 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-126-444-Each-of-1 In Stock ₹ 67,763.52

89-126-444 - Each of 1

₹ 67,763.52

In Stock

Quantity

1

Base Price: ₹ 67,763.52

GST (18%): ₹ 12,197.434

Total Price: ₹ 79,960.954

Antigen

TP53

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of TP53.

Formulation

In PBS, pH 7.2 (0.09% sodium azide)

Gene Alias

FLJ92943/LFS1/TRP53/p53

Host Species

Rabbit

Purification Method

Antigen affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

7157

Target Species

Human

Form

Liquid

Applications

Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.

Gene

TP53

Gene Symbols

TP53

Immunogen

A synthetic peptide corresponding to TP53.

Quantity

100 μL

Primary or Secondary

Primary

Test Specificity

TP53 polyclonal antibody detects endogenous levels of TP53 protein.

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism
  • p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy
  • p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains
  • It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor
  • Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity
  • Alterations of this gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome
  • Multiple p53 variants due to alternative promoters and multiple alternative splicing have been found
  • These variants encode distinct isoforms, which can regulate p53 transcriptional activity
  • [provided by RefSeq]

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Img

Abnova Corporation

89-126-444

--


Antigen:
TP53

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of TP53.

Formulation:
In PBS, pH 7.2 (0.09% sodium azide)

Gene Alias:
FLJ92943/LFS1/TRP53/p53

Host Species:
Rabbit

Purification Method:
Antigen affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.

Gene:
TP53

Gene Symbols:
TP53

Immunogen:
A synthetic peptide corresponding to TP53.

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
TP53 polyclonal antibody detects endogenous levels of TP53 protein.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-126-445

--


Antigen:
TP53

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of TP53.

Formulation:
In PBS, pH 7.2 (0.05% sodium azide)

Gene Alias:
FLJ92943/LFS1/TRP53/p53

Host Species:
Rabbit

Purification Method:
Antigen affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Target Species:
Human

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) Immunofluorescence (1:50-1:200) The optimal working dilution should be determined by the end user.

Gene:
TP53

Gene Symbols:
TP53

Immunogen:
A synthetic peptide corresponding to TP53.

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
TP53 polyclonal antibody detects endogenous levels of TP53 protein.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-126-448

--


Antigen:
PML

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of PML.

Formulation:
In PBS, pH 7.2 (0.05% sodium azide)

Gene Alias:
MYL/PP8675/RNF71/TRIM19

Host Species:
Rabbit

Purification Method:
Antigen affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
5371

Target Species:
Human

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) Immunofluorescence (1:50-1:200) The optimal working dilution should be determined by the end user.

Gene:
PML

Gene Symbols:
PML

Immunogen:
A synthetic peptide corresponding to PML.

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
PML polyclonal antibody detects endogenous levels of PML protein.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-126-449

--


Antigen:
PSEN1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of PSEN1.

Formulation:
In PBS, pH 7.2 (0.05% sodium azide)

Gene Alias:
AD3/FAD/PS1/S182

Host Species:
Rabbit

Purification Method:
Antigen affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
5663

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.

Gene:
PSEN1

Gene Symbols:
PSEN1

Immunogen:
A synthetic peptide corresponding to PSEN1.

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
PSEN1 polyclonal antibody detects endogenous levels of PSEN1 protein.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.