89-126-983

BRCA1 (phospho S1524), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-126-983-Each-of-1 In Stock ₹ 54,929.52

89-126-983 - Each of 1

₹ 54,929.52

In Stock

Quantity

1

Base Price: ₹ 54,929.52

GST (18%): ₹ 9,887.314

Total Price: ₹ 64,816.834

Antigen

BRCA1

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of BRCA1.

Formulation

In PBS (without mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Accession No.

P38398

Gene Symbols

BRCA1

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding S1524 of human BRCA1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (PFA fixed)

Conjugate

Unconjugated

Dilution

Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.

Gene

BRCA1

Gene Alias

BRCAI/BRCC1/IRIS/PSCP/RNF53

Host Species

Rabbit

Purification Method

Affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

672

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Description

  • This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor
  • The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC)
  • This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes
  • This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination
  • Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers
  • Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene
  • Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described
  • A related pseudogene, which is also located on chromosome 17, has been identified
  • [provided by RefSeq Sequence: Y-P-Sp-Q-E

Compare Similar Items

Show Difference

Img

Abnova Corporation

89-126-983

--


Antigen:
BRCA1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of BRCA1.

Formulation:
In PBS (without mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Accession No.:
P38398

Gene Symbols:
BRCA1

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S1524 of human BRCA1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed)

Conjugate:
Unconjugated

Dilution:
Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.

Gene:
BRCA1

Gene Alias:
BRCAI/BRCC1/IRIS/PSCP/RNF53

Host Species:
Rabbit

Purification Method:
Affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
672

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-126-985

--


Antigen:
CDC25A

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of CDC25A.

Formulation:
In PBS (without mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Accession No.:
P30304

Gene Symbols:
CDC25A

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S75 of human CDC25A.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.

Gene:
CDC25A

Gene Alias:
CDC25A2

Host Species:
Rabbit

Purification Method:
Affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
993

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-126-986

--


Antigen:
CDC25C

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of CDC25C.

Formulation:
In PBS (without mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Accession No.:
P30307

Gene Symbols:
CDC25C

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S216 of human CDC25C.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (PFA fixed)

Conjugate:
Unconjugated

Dilution:
Immunohistochemistry (1:50-1:100) Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.

Gene:
CDC25C

Gene Alias:
CDC25

Host Species:
Rabbit

Purification Method:
Affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
995

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-126-989

--


Antigen:
CTNNB1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of CTNNB1.

Formulation:
In PBS (without mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Accession No.:
P35222

Gene Symbols:
CTNNB1

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding T41/S45 of human CTNNB1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.

Gene:
CTNNB1

Gene Alias:
CTNNB/DKFZp686D02253/FLJ25606/FLJ37923

Host Species:
Rabbit

Purification Method:
Affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
1499

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.