89-128-307

TP53 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-128-307-Each-of-1 In Stock ₹ 51,079.32

89-128-307 - Each of 1

₹ 51,079.32

In Stock

Quantity

1

Base Price: ₹ 51,079.32

GST (18%): ₹ 9,194.278

Total Price: ₹ 60,273.598

Antigen

TP53

Classification

Polyclonal

Conjugate

Unconjugated

Dilution

Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.

Gene

TP53

Gene Symbols

TP53

Immunogen

A synthetic peptide corresponding to residues surrounding S33 of human TP53.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Description

Rabbit polyclonal antibody raised against synthetic peptide of TP53.

Formulation

In PBS (without Mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias

FLJ92943/LFS1/TRP53/p53

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7157

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism
  • p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy
  • p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains
  • It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor
  • Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity
  • Alterations of this gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome
  • Multiple p53 variants due to alternative promoters and multiple alternative splicing have been found
  • These variants encode distinct isoforms, which can regulate p53 transcriptional activity
  • [provided by RefSeq] Sequence: V-L-Sp-P-L

Compare Similar Items

Show Difference

Img

Abnova Corporation

89-128-307

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Antigen:
TP53

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.

Gene:
TP53

Gene Symbols:
TP53

Immunogen:
A synthetic peptide corresponding to residues surrounding S33 of human TP53.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Description:
Rabbit polyclonal antibody raised against synthetic peptide of TP53.

Formulation:
In PBS (without Mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias:
FLJ92943/LFS1/TRP53/p53

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-128-308

--


Antigen:
CDKL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1:1000) The optimal working dilution should be determined by the end user.

Gene:
CDKL2

Gene Symbols:
CDKL2

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to internal region of human CDKL2.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
__

Description:
Rabbit polyclonal antibody raised against synthetic peptide of CDKL2.

Formulation:
In PBS (0.09% sodium azide)

Gene Alias:
KKIAMRE/P56

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
8999

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-128-309

--


Antigen:
TP53

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.

Gene:
TP53

Gene Symbols:
TP53

Immunogen:
A synthetic peptide corresponding to residues surrounding S37 of human TP53.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Description:
Rabbit polyclonal antibody raised against synthetic peptide of TP53.

Formulation:
In PBS (without Mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias:
FLJ92943/LFS1/TRP53/p53

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-128-310

--


Antigen:
TP53

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.

Gene:
TP53

Gene Symbols:
TP53

Immunogen:
A synthetic peptide corresponding to residues surrounding S46 of human TP53.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Description:
Rabbit polyclonal antibody raised against synthetic peptide of TP53.

Formulation:
In PBS (without Mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias:
FLJ92943/LFS1/TRP53/p53

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.