89-128-490
CHEK2 Rabbit anti-Human, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-128-490-Each-of-1 | In Stock | ₹ 51,079.32 |
89-128-490 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,079.32
GST (18%): ₹ 9,194.278
Total Price: ₹ 60,273.598
Antigen
CHEK2
Classification
Polyclonal
Conjugate
Unconjugated
Dilution
Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
Gene
CHEK2
Gene Alias
CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11200
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications
Immunohistochemistry (PFA fixed)
Concentration
1 mg/mL
Description
Rabbit polyclonal antibody raised against synthetic peptide of CHEK2.
Formulation
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.
O96017
Gene Symbols
CHEK2
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S33 of human CHEK2.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators
- The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor
- It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage
- When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1
- In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage
- Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53
- Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors
- This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases
- Three transcript variants encoding different isoforms have been found for this gene
- [provided by RefSeq Sequence: S-S-Sp-Q-S
Compare Similar Items
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Antigen: CHEK2
Classification: Polyclonal
Conjugate: Unconjugated
Dilution: Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
Gene: CHEK2
Gene Alias: CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11200
Content And Storage: Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications: Immunohistochemistry (PFA fixed)
Concentration: 1 mg/mL
Description: Rabbit polyclonal antibody raised against synthetic peptide of CHEK2.
Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.: O96017
Gene Symbols: CHEK2
Immunogen: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S33 of human CHEK2.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
CHEK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Dilution:
Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
Gene:
CHEK2
Gene Alias:
CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11200
Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications:
Immunohistochemistry (PFA fixed)
Concentration:
1 mg/mL
Description:
Rabbit polyclonal antibody raised against synthetic peptide of CHEK2.
Formulation:
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.:
O96017
Gene Symbols:
CHEK2
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S33 of human CHEK2.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Antigen: ABL1/ABL2
Classification: Polyclonal
Conjugate: Unconjugated
Dilution: Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
Gene: __
Gene Alias: ABL/JTK7/bcr/abl/c-ABL/p150/v-abl
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 25/27
Content And Storage: Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications: Immunohistochemistry (PFA fixed)
Concentration: 1 mg/mL
Description: Rabbit polyclonal antibody raised against synthetic peptide of ABL1/ABL2.
Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.: P00519 (Gene ID : 25);P42684 (Gene ID : 27)
Gene Symbols: ABL1
Immunogen: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y393/Y429 of human ABL1/ABL2.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Liquid
Antigen:
ABL1/ABL2
Classification:
Polyclonal
Conjugate:
Unconjugated
Dilution:
Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
Gene:
__
Gene Alias:
ABL/JTK7/bcr/abl/c-ABL/p150/v-abl
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
25/27
Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications:
Immunohistochemistry (PFA fixed)
Concentration:
1 mg/mL
Description:
Rabbit polyclonal antibody raised against synthetic peptide of ABL1/ABL2.
Formulation:
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.:
P00519 (Gene ID : 25);P42684 (Gene ID : 27)
Gene Symbols:
ABL1
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y393/Y429 of human ABL1/ABL2.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Liquid
Antigen: STAT2
Classification: Polyclonal
Conjugate: Unconjugated
Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
Gene: STAT2
Gene Alias: ISGF-3/MGC59816/P113/STAT113
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6773
Content And Storage: Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications: Immunohistochemistry (PFA fixed), Western Blot
Concentration: 1 mg/mL
Description: Rabbit polyclonal antibody raised against synthetic peptide of STAT2.
Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.: __
Gene Symbols: STAT2
Immunogen: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y690 of human STAT2.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
STAT2
Classification:
Polyclonal
Conjugate:
Unconjugated
Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
Gene:
STAT2
Gene Alias:
ISGF-3/MGC59816/P113/STAT113
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6773
Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications:
Immunohistochemistry (PFA fixed), Western Blot
Concentration:
1 mg/mL
Description:
Rabbit polyclonal antibody raised against synthetic peptide of STAT2.
Formulation:
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.:
__
Gene Symbols:
STAT2
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y690 of human STAT2.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Antigen: PXN
Classification: Polyclonal
Conjugate: Unconjugated
Dilution: Western Blot (1:500-1:1000) Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.
Gene: PXN
Gene Alias: FLJ16691
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5829
Content And Storage: Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications: Immunofluorescence, Western Blot
Concentration: 1 mg/mL
Description: Rabbit polyclonal antibody raised against synthetic peptide of PXN.
Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.: __
Gene Symbols: PXN
Immunogen: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y88 of human PXN.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
PXN
Classification:
Polyclonal
Conjugate:
Unconjugated
Dilution:
Western Blot (1:500-1:1000) Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.
Gene:
PXN
Gene Alias:
FLJ16691
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5829
Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications:
Immunofluorescence, Western Blot
Concentration:
1 mg/mL
Description:
Rabbit polyclonal antibody raised against synthetic peptide of PXN.
Formulation:
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Accession No.:
__
Gene Symbols:
PXN
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y88 of human PXN.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid