89-130-037
CHEK2 Rabbit anti-Human, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-130-037-Each-of-1 | In Stock | ₹ 67,763.52 |
89-130-037 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 67,763.52
GST (18%): ₹ 12,197.434
Total Price: ₹ 79,960.954
Antigen
CHEK2
Classification
Polyclonal
Description
Rabbit polyclonal antibody raised against recombinant CHEK2.
Formulation
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Gene Accession No.
E7EPP1
Gene Symbols
CHEK2
Immunogen
Recombinant protein corresponding to amino acids of human CHEK2.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunohistochemistry (PFA fixed), Western Blot
Conjugate
Unconjugated
Dilution
Western Blot (1:100-1:250) Immunohistochemistry (1:10-1:20) The optimal working dilution should be determined by the end user.
Gene
CHEK2
Gene Alias
CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species
Rabbit
Purification Method
Antigen affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
11200
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG
Description
- In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators
- The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor
- It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage
- When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1
- In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage
- Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53
- Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors
- This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases
- Three transcript variants encoding different isoforms have been found for this gene
- [provided by RefSeq Sequence: TSTMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNG
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Antigen: CHEK2
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against recombinant CHEK2.
Formulation: In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Gene Accession No.: E7EPP1
Gene Symbols: CHEK2
Immunogen: Recombinant protein corresponding to amino acids of human CHEK2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (PFA fixed), Western Blot
Conjugate: Unconjugated
Dilution: Western Blot (1:100-1:250) Immunohistochemistry (1:10-1:20) The optimal working dilution should be determined by the end user.
Gene: CHEK2
Gene Alias: CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species: Rabbit
Purification Method: Antigen affinity purification
Regulatory Status: RUO
Gene ID (Entrez): 11200
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG
Antigen:
CHEK2
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against recombinant CHEK2.
Formulation:
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Gene Accession No.:
E7EPP1
Gene Symbols:
CHEK2
Immunogen:
Recombinant protein corresponding to amino acids of human CHEK2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (PFA fixed), Western Blot
Conjugate:
Unconjugated
Dilution:
Western Blot (1:100-1:250) Immunohistochemistry (1:10-1:20) The optimal working dilution should be determined by the end user.
Gene:
CHEK2
Gene Alias:
CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species:
Rabbit
Purification Method:
Antigen affinity purification
Regulatory Status:
RUO
Gene ID (Entrez):
11200
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG
Antigen: TAF7L
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against recombinant TAF7L.
Formulation: In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Gene Accession No.: __
Gene Symbols: TAF7L
Immunogen: Recombinant protein corresponding to amino acids of human TAF7L.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (PFA fixed)
Conjugate: Unconjugated
Dilution: Immunofluorescence (1-4 ug/ml) Immunohistochemistry (1:10-1:20) The optimal working dilution should be determined by the end user.
Gene: TAF7L
Gene Alias: FLJ23157/TAF2Q/dJ738A13.1
Host Species: Rabbit
Purification Method: Antigen affinity purification
Regulatory Status: RUO
Gene ID (Entrez): 54457
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG
Antigen:
TAF7L
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against recombinant TAF7L.
Formulation:
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Gene Accession No.:
__
Gene Symbols:
TAF7L
Immunogen:
Recombinant protein corresponding to amino acids of human TAF7L.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (PFA fixed)
Conjugate:
Unconjugated
Dilution:
Immunofluorescence (1-4 ug/ml) Immunohistochemistry (1:10-1:20) The optimal working dilution should be determined by the end user.
Gene:
TAF7L
Gene Alias:
FLJ23157/TAF2Q/dJ738A13.1
Host Species:
Rabbit
Purification Method:
Antigen affinity purification
Regulatory Status:
RUO
Gene ID (Entrez):
54457
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG
Antigen: PQBP1
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against recombinant PQBP1.
Formulation: In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Gene Accession No.: __
Gene Symbols: PQBP1
Immunogen: Recombinant protein corresponding to amino acids of human PQBP1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate: Unconjugated
Dilution: Immunofluorescence (1-4 ug/ml) Immunohistochemistry (1:200-1:500) The optimal working dilution should be determined by the end user.
Gene: PQBP1
Gene Alias: MRX55/MRXS3/MRXS8/NPW38/RENS1/SHS
Host Species: Rabbit
Purification Method: Antigen affinity purification
Regulatory Status: RUO
Gene ID (Entrez): 10084
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG
Antigen:
PQBP1
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against recombinant PQBP1.
Formulation:
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Gene Accession No.:
__
Gene Symbols:
PQBP1
Immunogen:
Recombinant protein corresponding to amino acids of human PQBP1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate:
Unconjugated
Dilution:
Immunofluorescence (1-4 ug/ml) Immunohistochemistry (1:200-1:500) The optimal working dilution should be determined by the end user.
Gene:
PQBP1
Gene Alias:
MRX55/MRXS3/MRXS8/NPW38/RENS1/SHS
Host Species:
Rabbit
Purification Method:
Antigen affinity purification
Regulatory Status:
RUO
Gene ID (Entrez):
10084
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG
Antigen: NUP62CL
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against recombinant NUP62CL.
Formulation: In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Gene Accession No.: __
Gene Symbols: NUP62CL
Immunogen: Recombinant protein corresponding to amino acids of human NUP62CL.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry, Immunohistochemistry (Formalin/Paraffin)
Conjugate: Unconjugated
Dilution: Immunohistochemistry (1:200-1:500) The optimal working dilution should be determined by the end user.
Gene: NUP62CL
Gene Alias: FLJ20130
Host Species: Rabbit
Purification Method: Antigen affinity purification
Regulatory Status: RUO
Gene ID (Entrez): 54830
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG
Antigen:
NUP62CL
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against recombinant NUP62CL.
Formulation:
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Gene Accession No.:
__
Gene Symbols:
NUP62CL
Immunogen:
Recombinant protein corresponding to amino acids of human NUP62CL.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry, Immunohistochemistry (Formalin/Paraffin)
Conjugate:
Unconjugated
Dilution:
Immunohistochemistry (1:200-1:500) The optimal working dilution should be determined by the end user.
Gene:
NUP62CL
Gene Alias:
FLJ20130
Host Species:
Rabbit
Purification Method:
Antigen affinity purification
Regulatory Status:
RUO
Gene ID (Entrez):
54830
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG