89-130-729

TP53 (phospho T387), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-130-729-Each-of-1 In Stock ₹ 54,929.52

89-130-729 - Each of 1

₹ 54,929.52

In Stock

Quantity

1

Base Price: ₹ 54,929.52

GST (18%): ₹ 9,887.314

Total Price: ₹ 64,816.834

Antigen

TP53

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human TP53.

Formulation

In PBS (without Mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias

FLJ92943/LFS1/TRP53/p53

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7157

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunohistochemistry (PFA fixed)

Conjugate

Unconjugated

Dilution

Immunohistochemistry (1:50∼1:100) The optimal working dilution should be determined by the end user.

Gene

TP53

Gene Symbols

TP53

Immunogen

Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T387 of human TP53.

Quantity

100 μL

Primary or Secondary

Primary

Test Specificity

TP53 (phospho T387) polyclonal antibody detects endogenous levels of human TP53 only when phosphorylated at threonine 387.

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism
  • p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy
  • p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains
  • It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor
  • Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity
  • Alterations of this gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome
  • Multiple p53 variants due to alternative promoters and multiple alternative splicing have been found
  • These variants encode distinct isoforms, which can regulate p53 transcriptional activity
  • [provided by RefSeq]

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Img

Abnova Corporation

89-130-729

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Antigen:
TP53

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human TP53.

Formulation:
In PBS (without Mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias:
FLJ92943/LFS1/TRP53/p53

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed)

Conjugate:
Unconjugated

Dilution:
Immunohistochemistry (1:50∼1:100) The optimal working dilution should be determined by the end user.

Gene:
TP53

Gene Symbols:
TP53

Immunogen:
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T387 of human TP53.

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
TP53 (phospho T387) polyclonal antibody detects endogenous levels of human TP53 only when phosphorylated at threonine 387.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Antigen:
CSNK1A1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CSNK1A1.

Formulation:
In PBS (without mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias:
CK1/HLCDGP1/PRO2975

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1452

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Immunohistochemistry (1:50∼1:100) Western Blot (1:500∼1:1000) The optimal working dilution should be determined by the end user.

Gene:
CSNK1A1

Gene Symbols:
CSNK1A1

Immunogen:
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y294 of human CSNK1A1.

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
CSNK1A1 (phospho Y294) polyclonal antibody detects endogenous levels of human CSNK1A1 only when phosphorylated at tyrosine 294.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Antigen:
DYRK3

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of DYRK3.

Formulation:
In PBS (0.09% sodium azide)

Gene Alias:
DYRK5/RED/REDK/hYAK3-2

Host Species:
Rabbit

Purification Method:
Protein G purification

Regulatory Status:
RUO

Gene ID (Entrez):
8444

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1:1000) The optimal working dilution should be determined by the end user.

Gene:
DYRK3

Gene Symbols:
DYRK3

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human DYRK3.

Quantity:
400 μL

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Antigen:
ILK

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human ILK.

Formulation:
In PBS (without Mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias:
DKFZp686F1765/P59

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3611

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed)

Conjugate:
Unconjugated

Dilution:
Immunohistochemistry (1:50∼1:100) The optimal working dilution should be determined by the end user.

Gene:
ILK

Gene Symbols:
ILK

Immunogen:
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S246 of human ILK.

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
ILK (phospho S246) polyclonal antibody detects endogenous levels of human ILK only when phosphorylated at serine 246.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.