89-131-660

KNG1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-131-660-Each-of-1 In Stock ₹ 51,079.32

89-131-660 - Each of 1

₹ 51,079.32

In Stock

Quantity

1

Base Price: ₹ 51,079.32

GST (18%): ₹ 9,194.278

Total Price: ₹ 60,273.598

Antigen

KNG1

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of KNG1.

Formulation

In PBS, pH 7.5 (50% glycerol, 0.01% thimerosal)

Gene Alias

BDK/KNG

Host Species

Rabbit

Quantity

150 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunoprecipitation

Conjugate

Unconjugated

Dilution

The optimal working dilution should be determined by the end user.

Gene

KNG1

Gene Symbols

KNG1

Immunogen

A synthetic peptide (conjugated with KLH) corresponding to human KNG1.

Regulatory Status

RUO

Gene ID (Entrez)

3827

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • High molecular weight kininogen (HMWK) plays an important role in assembly of the plasma kallikrein (see MIM 147910)-kinin system
  • The KNG1 gene generates both HMWK and low molecular weight kininogen (LMWK) through alternative splicing
  • Both HMWK and LMWK contain an identical heavy chain consisting of protein domains 1, 2, and 3
  • However, HMWK contains a 56kDa light chain that consists of domains 5 and 6H, whereas LMWK contains a unique 4kDa light chain that consists of domain 5L
  • In both proteins, the heavy and light chains are linked by domain 4, which contains the bradykinin (BK) nonapeptide
  • BK, which is released by plasma kallikrein, is a potent inflammatory mediator that causes vasodilation and enhanced capillary permeability, induces pain, and stimulates production of nitric oxide and prostacyclin (see MIM 601699) from endothelial cells
  • During vascular damage, BK stimulates smooth muscle proliferation and intimal hypertrophy
  • Release of BK from HMWK generates a 2-chain HMWK, termed HMWKa, containing the heavy and light chains joined by a disulfide bond (Merkulov et al., 2008 [PubMed 18000168]).[supplied by OMIM Sequence: CRPPGFSPFR

Compare Similar Items

Show Difference

Img

Abnova Corporation

89-131-660

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Antigen:
KNG1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of KNG1.

Formulation:
In PBS, pH 7.5 (50% glycerol, 0.01% thimerosal)

Gene Alias:
BDK/KNG

Host Species:
Rabbit

Quantity:
150 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunoprecipitation

Conjugate:
Unconjugated

Dilution:
The optimal working dilution should be determined by the end user.

Gene:
KNG1

Gene Symbols:
KNG1

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to human KNG1.

Regulatory Status:
RUO

Gene ID (Entrez):
3827

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-131-663

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Antigen:
CORT

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of CORT.

Formulation:
In PBS, pH 7.5 (50% glycerol, 0.01% thimerosal)

Gene Alias:
CST-14/CST-17/CST-29

Host Species:
Rabbit

Quantity:
150 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunoprecipitation

Conjugate:
Unconjugated

Dilution:
The optimal working dilution should be determined by the end user.

Gene:
CORT

Gene Symbols:
CORT

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to human CORT.

Regulatory Status:
RUO

Gene ID (Entrez):
1325

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

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89-131-664

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Antigen:
PDYN

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of PDYN.

Formulation:
In PBS, pH 7.5 (50% glycerol, 0.01% thimerosal)

Gene Alias:
MGC26418/PENKB

Host Species:
Rabbit

Quantity:
150 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunoprecipitation

Conjugate:
Unconjugated

Dilution:
The optimal working dilution should be determined by the end user.

Gene:
PDYN

Gene Symbols:
PDYN

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to amino acids 1-17 of human PDYN.

Regulatory Status:
RUO

Gene ID (Entrez):
5173

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Antigen:
EDN3

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of EDN3.

Formulation:
In PBS, pH 7.5 (50% glycerol, 0.01% thimerosal)

Gene Alias:
ET3/MGC15067/MGC61498

Host Species:
Rabbit

Quantity:
150 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunoprecipitation

Conjugate:
Unconjugated

Dilution:
The optimal working dilution should be determined by the end user.

Gene:
EDN3

Gene Symbols:
EDN3

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to human EDN3.

Regulatory Status:
RUO

Gene ID (Entrez):
1908

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.