89-133-791

CASP1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-133-791-Each-of-1 In Stock ₹ 1,00,276.32

89-133-791 - Each of 1

₹ 1,00,276.32

In Stock

Quantity

1

Base Price: ₹ 1,00,276.32

GST (18%): ₹ 18,049.738

Total Price: ₹ 1,18,326.058

Antigen

CASP1

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of CASP1.

Formulation

In PBS, pH 7.2 (30% glycerol, 0.5mg/mL BSA, 0.01% thimerosal)

Gene Accession No.

NP_150636

Gene Symbols

CASP1

Immunogen

A synthetic peptide corresponding to residues surrounding amino acids 132 of human CASP1.

Regulatory Status

RUO

Gene ID (Entrez)

834

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunofluorescence, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (0.5-4 ug/mL) Immunoprecipitation (4-8 ug/mL) Immunofluorescence (10-20 ug/mL) The optimal working dilution should be determined by the end user.

Gene

CASP1

Gene Alias

ICE/IL1BC/P45

Host Species

Rabbit

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

The immunoaffinity purified antibody recognizes 45 KDa procaspase-1 and the 20 KDa cleaved product.

Content And Storage

Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Description

  • This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family
  • Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis
  • Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme
  • This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing
  • This gene has been shown to induce cell apoptosis and may function in various developmental stages
  • Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease
  • Alternative splicing of this gene results in five transcript variants encoding distinct isoforms
  • [provided by RefSeq

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Abnova Corporation

89-133-791

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Antigen:
CASP1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of CASP1.

Formulation:
In PBS, pH 7.2 (30% glycerol, 0.5mg/mL BSA, 0.01% thimerosal)

Gene Accession No.:
NP_150636

Gene Symbols:
CASP1

Immunogen:
A synthetic peptide corresponding to residues surrounding amino acids 132 of human CASP1.

Regulatory Status:
RUO

Gene ID (Entrez):
834

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunofluorescence, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.5-4 ug/mL) Immunoprecipitation (4-8 ug/mL) Immunofluorescence (10-20 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
CASP1

Gene Alias:
ICE/IL1BC/P45

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
The immunoaffinity purified antibody recognizes 45 KDa procaspase-1 and the 20 KDa cleaved product.

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-133-793

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Antigen:
Casp4

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of Casp4.

Formulation:
In PBS, pH 7.2 (30% glycerol, 0.5mg/mL BSA, 0.01% thimerosal)

Gene Accession No.:
__

Gene Symbols:
Casp4

Immunogen:
A synthetic peptide corresponding to residues surrounding amino acids 257 of rat Casp4.

Regulatory Status:
RUO

Gene ID (Entrez):
114555

Target Species:
Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.5-4 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
Casp4

Gene Alias:
Casp11/MGC124949

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody detects procaspase-11 (45 KDa), a partially cleaved fragment (30 KDa) and fully cleaved fragment (20 KDa). A 58 KDa unknown identity band was also detected in 3T3 cells.

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-133-794

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Antigen:
Casp12

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of Casp12.

Formulation:
In PBS, pH 7.2 (30% glycerol, 0.5mg/mL BSA, 0.01% thimerosal)

Gene Accession No.:
__

Gene Symbols:
Casp12

Immunogen:
A synthetic peptide corresponding to residues surrounding amino acids 310 of mouse Casp12.

Regulatory Status:
RUO

Gene ID (Entrez):
12364

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.5-4 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
Casp12

Gene Alias:
__

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-133-795

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Antigen:
Casp2

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of Casp2.

Formulation:
In PBS, pH 7.2 (30% glycerol, 0.5mg/mL BSA, 0.01% thimerosal)

Gene Accession No.:
__

Gene Symbols:
Casp2

Immunogen:
A synthetic peptide corresponding to residues surrounding amino acids 417 of mouse Casp2.

Regulatory Status:
RUO

Gene ID (Entrez):
12366

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
Casp2

Gene Alias:
Caspase-2/ICH-1/Nedd2

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Detects the full length and small subunit of caspase-2. In human samples, it also detects a 30 KDa intermeadiate fragment.

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.