89-133-805

CASP8 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-133-805-Each-of-1 In Stock ₹ 54,929.52

89-133-805 - Each of 1

₹ 54,929.52

In Stock

Quantity

1

Base Price: ₹ 54,929.52

GST (18%): ₹ 9,887.314

Total Price: ₹ 64,816.834

Antigen

CASP8

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of CASP8.

Formulation

In PBS, pH 7.2 (30% glycerol, 0.5mg/mL BSA, 0.01% thimerosal)

Gene Alias

ALPS2B/CAP4/FLICE/FLJ17672/MACH/MCH5/MGC78473

Host Species

Rabbit

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

The affinity purified antibody mainly detects the 26 KDa fully cleaved fragment and the 35-43 KDa intermediate of caspase-8 in apoptotic samples.

Content And Storage

Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Applications

Immunohistochemistry, Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (0.5-4 ug/mL) Immunohistochemistry (10-20 mg/mL) The optimal working dilution should be determined by the end user.

Gene

CASP8

Gene Symbols

CASP8

Immunogen

A synthetic peptide corresponding to the cleavage site of human CASP8.

Regulatory Status

RUO

Gene ID (Entrez)

841

Target Species

Human

Form

Liquid

Description

  • This gene encodes a member of the cysteine-aspartic acid protease (caspase) family
  • Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis
  • Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit
  • Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits
  • This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli
  • The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD
  • This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases
  • Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined
  • [provided by RefSeq

Compare Similar Items

Show Difference

Img

Abnova Corporation

89-133-805

--


Antigen:
CASP8

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of CASP8.

Formulation:
In PBS, pH 7.2 (30% glycerol, 0.5mg/mL BSA, 0.01% thimerosal)

Gene Alias:
ALPS2B/CAP4/FLICE/FLJ17672/MACH/MCH5/MGC78473

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
The affinity purified antibody mainly detects the 26 KDa fully cleaved fragment and the 35-43 KDa intermediate of caspase-8 in apoptotic samples.

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.5-4 ug/mL) Immunohistochemistry (10-20 mg/mL) The optimal working dilution should be determined by the end user.

Gene:
CASP8

Gene Symbols:
CASP8

Immunogen:
A synthetic peptide corresponding to the cleavage site of human CASP8.

Regulatory Status:
RUO

Gene ID (Entrez):
841

Target Species:
Human

Form:
Liquid

Img

Abnova Corporation

89-133-806

--


Antigen:
Casp9

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of Casp9.

Formulation:
In PBS, pH 7.2 (30% glycerol, 0.5mg/mL BSA, 0.01% thimerosal)

Gene Alias:
AI115399/AW493809/Caspase-9/ICE-LAP6/Mch6

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody detects 45 KDa procaspase-9, 35-37 KDa cleaved immediate fragments and the 17-25 KDa fully cleaved caspase-9.

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Applications:
Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.5-4 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
Casp9

Gene Symbols:
Casp9

Immunogen:
A synthetic peptide corresponding to residues surrounding amino acids 290 of mouse Casp9.

Regulatory Status:
RUO

Gene ID (Entrez):
12371

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Abnova Corporation

89-133-808

--


Antigen:
CTSB

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of CTSB.

Formulation:
In PBS, pH 7.2 (30% glycerol, 0.5mg/mL BSA, 0.01% thimerosal)

Gene Alias:
APPS/CPSB

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
The purified antibody detects both the proform (37-43 KDa) and the mature form (25 KDa) of cathepsin B. It reacts with human and mouse and in a lesser extent with rat samples.

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.5-4 ug/mL) Immunohistochemistry (10-20 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
CTSB

Gene Symbols:
CTSB

Immunogen:
A synthetic peptide corresponding to residues surrounding amino acids 322 of human CTSB.

Regulatory Status:
RUO

Gene ID (Entrez):
1508

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Abnova Corporation

89-133-812

--


Antigen:
Ctsl1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of Ctsl1.

Formulation:
In PBS (30% glycerol, 0.5% BSA, 0.02% thimerosal)

Gene Alias:
CATHL/Ctsl

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes the mature form of Cathepsin L (25 KDa).

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Applications:
Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.5-4 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
Ctsl1

Gene Symbols:
Ctsl1

Immunogen:
A synthetic peptide corresponding to residues surrounding amino acids 223 of rat Ctsl1.

Regulatory Status:
RUO

Gene ID (Entrez):
25697

Target Species:
Human, Mouse, Rat

Form:
Liquid