89-334-011

MPL Mouse anti-Human, Clone:1D6B7, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-334-011-Each-of-1 In Stock ₹ 59,121.96

89-334-011 - Each of 1

₹ 59,121.96

In Stock

Quantity

1

Base Price: ₹ 59,121.96

GST (18%): ₹ 10,641.953

Total Price: ₹ 69,763.913

Antigen

MPL

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

ELISA (1:10000)Western Blot (1:500-1:2000)ImmunocytochemistryFlow Cytometry (1:200-1:400)ImmunohistochemistryThe optimal working dilution should be determined by the end user.

Gene

MPL

Host Species

Mouse

Quantity

100 μg

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

ELISA, Flow Cytometry, Western Blot

Clone

1D6B7

Description

myeloproliferative leukemia virus oncogene

Formulation

In PBS (0.05% sodium azide)

Gene Alias

C-MPL, CD110, MPLV, TPOR

Immunogen

Recombinant protein corresponding to amino acid 26-175 of human MPL fromE. coli.

Gene ID (Entrez)

4352

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Form

Liquid

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Description

  • In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages
  • In 1992 the human homologue, named, c-mpl, was cloned
  • Sequence data revealed that c-mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily
  • Presence of anti-sense oligodeoxynucleotides of c-mpl inhibited megakaryocyte colony formation
  • The ligand for c-mpl, thrombopoietin, was cloned in 1994
  • Thrombopoietin was shown to be the major regulator of megakaryocytopoiesis and platelet formation
  • The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs
  • TPO-R deficient mice were severely thrombocytopenic, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation
  • Upon binding of thrombopoietin CD110 is dimerized and the JAK family of non-receptor tyrosine kinases, as well as the STAT family, the MAPK family, the adaptor protein Shc and the receptors themselves become tyrosine phosphorylated
  • [provided by RefSeq]

Compare Similar Items

Show Difference

Img

Abnova Corporation

89-334-011

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Antigen:
MPL

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
ELISA (1:10000)Western Blot (1:500-1:2000)ImmunocytochemistryFlow Cytometry (1:200-1:400)ImmunohistochemistryThe optimal working dilution should be determined by the end user.

Gene:
MPL

Host Species:
Mouse

Quantity:
100 μg

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
1D6B7

Description:
myeloproliferative leukemia virus oncogene

Formulation:
In PBS (0.05% sodium azide)

Gene Alias:
C-MPL, CD110, MPLV, TPOR

Immunogen:
Recombinant protein corresponding to amino acid 26-175 of human MPL fromE. coli.

Gene ID (Entrez):
4352

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Form:
Liquid

Img

Abnova Corporation

89-334-012

--


Antigen:
P2RY4

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
ELISA (1:10000)Western Blot (1:500-1:2000)ImmunocytochemistryFlow CytometryImmunohistochemistry (1:200-1:1000)The optimal working dilution should be determined by the end user.

Gene:
P2RY4

Host Species:
Mouse

Quantity:
100 μg

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone:
3B4C11

Description:
pyrimidinergic receptor P2Y, G-protein coupled, 4

Formulation:
In PBS (0.05% sodium azide)

Gene Alias:
NRU, P2P, P2Y4, UNR

Immunogen:
Recombinant protein corresponding to amino acid of human P2RY4 fromE. coli.

Gene ID (Entrez):
5030

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Form:
Liquid

Img

Abnova Corporation

89-334-014

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Antigen:
GRIN2B

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
ELISA (1:10000)Western Blot (1:500-1:2000)Immunocytochemistry (1:100-1:500)Flow Cytometry (1:200-1:400)ImmunohistochemistryThe optimal working dilution should be determined by the end user.

Gene:
GRIN2B

Host Species:
Mouse

Quantity:
100 μg

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
6E9A8

Description:
glutamate receptor, ionotropic, N-methyl D-aspartate 2B

Formulation:
In PBS (0.05% sodium azide)

Gene Alias:
MGC142178, MGC142180, NMDAR2B, NR2B, hNR3

Immunogen:
Recombinant protein corresponding to amino acid 27-163 of human GRIN2B fromE. coli.

Gene ID (Entrez):
2904

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Form:
Liquid

Img

Abnova Corporation

89-334-015

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Antigen:
CCR3

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
ELISA (1:10000)Western Blot (1:500-1:2000)ImmunocytochemistryFlow Cytometry (1:200-1:400)ImmunohistochemistryThe optimal working dilution should be determined by the end user.

Gene:
CCR3

Host Species:
Mouse

Quantity:
100 μg

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
8E9H10

Description:
chemokine (C-C motif) receptor 3

Formulation:
In PBS (0.05% sodium azide)

Gene Alias:
CC-CKR-3, CD193, CKR3, CMKBR3, MGC102841

Immunogen:
Recombinant protein corresponding to amino acid of human CCR3 fromE. coli.

Gene ID (Entrez):
1232

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Form:
Liquid