89-334-469
PPP1R1B Mouse anti-Human, Clone:2A4G9, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-334-469-Each-of-1 | In Stock | ₹ 58,437.48 |
89-334-469 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 58,437.48
GST (18%): ₹ 10,518.746
Total Price: ₹ 68,956.226
Antigen
PPP1R1B
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
ELISA (1:10000)Flow CytometryImmunocytochemistryImmunohistochemistryWestern Blot (1:500-1:2000)The optimal working dilution should be determined by the end user.
Gene
PPP1R1B
Host Species
Mouse
Quantity
100 μg
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Western Blot
Clone
2A4G9
Description
protein phosphatase 1, regulatory (inhibitor) subunit 1B
Formulation
In PBS (0.05% sodium azide)
Gene Alias
DARPP-32, DARPP32, FLJ20940
Immunogen
Recombinant protein corresponding to amino acids 95-204 of human PPP1R1B fromE. coli.
Gene ID (Entrez)
84152
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Form
Liquid
Related Products
Description
- Midbrain dopaminergic neurons play a critical role in multiple brain functions, and abnormal signaling through dopaminergic pathways has been implicated in several major neurologic and psychiatric disorders
- One well-studied target for the actions of dopamine is DARPP32
- In the densely dopamine- and glutamate-innervated rat caudate-putamen, DARPP32 is expressed in medium-sized spiny neurons (Ouimet and Greengard, 1990 [PubMed 2191086]) that also express dopamine D1 receptors (Walaas and Greengard, 1984 [PubMed 6319627])
- The function of DARPP32 seems to be regulated by receptor stimulation
- Both dopaminergic and glutamatergic (NMDA) receptor stimulation regulate the extent of DARPP32 phosphorylation, but in opposite directions (Halpain et al., 1990 [PubMed 2153935])
- Dopamine D1 receptor stimulation enhances cAMP formation, resulting in the phosphorylation of DARPP32 (Walaas and Greengard, 1984 [PubMed 6319627]); phosphorylated DARPP32 is a potent protein phosphatase-1 (see MIM 176875) inhibitor (Hemmings et al., 1984 [PubMed 6087160])
- NMDA receptor stimulation elevates intracellular calcium, which leads to activation of calcineurin and dephosphorylation of phospho-DARPP32, thereby reducing the phosphatase-1 inhibitory activity of DARPP32 (Halpain et al., 1990 [PubMed 2153935]).[supplied by OMIM]
Compare Similar Items
Show Difference
Antigen: PPP1R1B
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: ELISA (1:10000)Flow CytometryImmunocytochemistryImmunohistochemistryWestern Blot (1:500-1:2000)The optimal working dilution should be determined by the end user.
Gene: PPP1R1B
Host Species: Mouse
Quantity: 100 μg
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Western Blot
Clone: 2A4G9
Description: protein phosphatase 1, regulatory (inhibitor) subunit 1B
Formulation: In PBS (0.05% sodium azide)
Gene Alias: DARPP-32, DARPP32, FLJ20940
Immunogen: Recombinant protein corresponding to amino acids 95-204 of human PPP1R1B fromE. coli.
Gene ID (Entrez): 84152
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Form: Liquid
Antigen:
PPP1R1B
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
ELISA (1:10000)Flow CytometryImmunocytochemistryImmunohistochemistryWestern Blot (1:500-1:2000)The optimal working dilution should be determined by the end user.
Gene:
PPP1R1B
Host Species:
Mouse
Quantity:
100 μg
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Western Blot
Clone:
2A4G9
Description:
protein phosphatase 1, regulatory (inhibitor) subunit 1B
Formulation:
In PBS (0.05% sodium azide)
Gene Alias:
DARPP-32, DARPP32, FLJ20940
Immunogen:
Recombinant protein corresponding to amino acids 95-204 of human PPP1R1B fromE. coli.
Gene ID (Entrez):
84152
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Form:
Liquid
Antigen: SMCP
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: ELISA (1:10000)Flow CytometryImmunocytochemistryImmunohistochemistryWestern Blot (1:500-1:2000)The optimal working dilution should be determined by the end user.
Gene: SMCP
Host Species: Mouse
Quantity: 100 μg
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: ELISA, Western Blot
Clone: 5C10A2
Description: sperm mitochondria-associated cysteine-rich protein
Formulation: In PBS (0.05% sodium azide)
Gene Alias: HSMCSGEN1, MCS, MCSP, MGC26305, MGC26519
Immunogen: Recombinant protein corresponding to amino acids 1-116 of human SMCP fromE. coli.
Gene ID (Entrez): 4184
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Form: Liquid
Antigen:
SMCP
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
ELISA (1:10000)Flow CytometryImmunocytochemistryImmunohistochemistryWestern Blot (1:500-1:2000)The optimal working dilution should be determined by the end user.
Gene:
SMCP
Host Species:
Mouse
Quantity:
100 μg
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
ELISA, Western Blot
Clone:
5C10A2
Description:
sperm mitochondria-associated cysteine-rich protein
Formulation:
In PBS (0.05% sodium azide)
Gene Alias:
HSMCSGEN1, MCS, MCSP, MGC26305, MGC26519
Immunogen:
Recombinant protein corresponding to amino acids 1-116 of human SMCP fromE. coli.
Gene ID (Entrez):
4184
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Form:
Liquid
Antigen: Psp
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: ELISA (1:10000)Flow Cytometry (1:200-1:400)ImmunocytochemistryImmunohistochemistry (1:200-1:1000)Western Blot (1:500-1:2000)The optimal working dilution should be determined by the end user.
Gene: Psp
Host Species: Mouse
Quantity: 100 μg
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone: 3F8E4
Description: parotid secretory protein
Formulation: In PBS (0.05% sodium azide)
Gene Alias: __
Immunogen: Recombinant protein corresponding to amino acids 16-169 of human Psp fromE. coli.
Gene ID (Entrez): 19194
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Form: Liquid
Antigen:
Psp
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
ELISA (1:10000)Flow Cytometry (1:200-1:400)ImmunocytochemistryImmunohistochemistry (1:200-1:1000)Western Blot (1:500-1:2000)The optimal working dilution should be determined by the end user.
Gene:
Psp
Host Species:
Mouse
Quantity:
100 μg
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone:
3F8E4
Description:
parotid secretory protein
Formulation:
In PBS (0.05% sodium azide)
Gene Alias:
__
Immunogen:
Recombinant protein corresponding to amino acids 16-169 of human Psp fromE. coli.
Gene ID (Entrez):
19194
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Form:
Liquid
Antigen: NBN
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: ELISA (1:10000)Flow Cytometry (1:200-1:400)Immunocytochemistry (1:200-1:1000)Immunohistochemistry (1:200-1:1000)Western Blot (1:500-1:2000)The optimal working dilution should be determined by the end user.
Gene: NBN
Host Species: Mouse
Quantity: 100 μg
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG2a
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 7E4A2
Description: nibrin
Formulation: In PBS (0.05% sodium azide)
Gene Alias: AT-V1, AT-V2, ATV, FLJ10155, MGC87362, NBS, NBS1, P95
Immunogen: Recombinant protein corresponding to amino acids 467-615 of human NBN fromE. coli.
Gene ID (Entrez): 4683
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Form: Liquid
Antigen:
NBN
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
ELISA (1:10000)Flow Cytometry (1:200-1:400)Immunocytochemistry (1:200-1:1000)Immunohistochemistry (1:200-1:1000)Western Blot (1:500-1:2000)The optimal working dilution should be determined by the end user.
Gene:
NBN
Host Species:
Mouse
Quantity:
100 μg
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
7E4A2
Description:
nibrin
Formulation:
In PBS (0.05% sodium azide)
Gene Alias:
AT-V1, AT-V2, ATV, FLJ10155, MGC87362, NBS, NBS1, P95
Immunogen:
Recombinant protein corresponding to amino acids 467-615 of human NBN fromE. coli.
Gene ID (Entrez):
4683
Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Form:
Liquid