ABC924MI
MilliporeSigma™ Rabbit anti-CtBP-2, Polyclonal,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABC924MI-Each-of-1 | In Stock | ₹ 41,307.51 |
ABC924MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,307.51
GST (18%): ₹ 7,435.352
Total Price: ₹ 48,742.862
Antigen
CtBP-2
Classification
Polyclonal
Gene Accession No.
P56545
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Applications
Immunohistochemistry, Western Blot
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
CTBP2
Immunogen
KLH-conjugated linear peptide corresponding to the C-terminus of human CtBP-2.
Quantity
100 μg
Research Discipline
Apoptosis, Cancer
Gene ID (Entrez)
NP_001077383
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
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Description
- Specifically detects CtBP-2 in Human samples, and it is validated for Immunohistochemistry, Western Blotting C-terminal-binding protein 2 (UniProt P56545; also known as CtBP2) is a nuclear protein encoded by the CTBP2 gene (Gene ID 1488) in human
- CtBP1 and CtBP2 are closely related proteins that are encoded by the vertebrate genome and perform both unique and duplicative functions
- Upon activation by nicotinamide adenine dinucleotide binding to their dehydrogenase domains, CtBP1 and CtBP2 exert transcriptional repression activity primarily via recruitment of a corepressor complex that consists of histone deacetylases (HDACs) and histone methyltransferases, although CtBPs can also repress transcription through HDAC-independent mechanisms
- A critical function of CtBPs lies in the transcriptional repression of pro-apoptotic genes such as Bax, Puma, Bik, and Noxa
- CtBP2 is essential for proper development of the nervous system
- Acetylation by histone acetyl transferase p300 regulates CtBP2 activity and subcellular localization, while microenvironmental oxygen levels influences the dimerization, acetylation, and thereby the activity of CtBP2 in proliferating neural stem cells (NSCs).
Compare Similar Items
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Antigen: CtBP-2
Classification: Polyclonal
Gene Accession No.: P56545
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Applications: Immunohistochemistry, Western Blot
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CTBP2
Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of human CtBP-2.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_001077383
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Antigen:
CtBP-2
Classification:
Polyclonal
Gene Accession No.:
P56545
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Applications:
Immunohistochemistry, Western Blot
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CTBP2
Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminus of human CtBP-2.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_001077383
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Antigen: AMACR
Classification: Polyclonal
Gene Accession No.: Q9UHK6
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Applications: Immunohistochemistry, Western Blot
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: AMACR
Immunogen: GST-tagged recombinant protein corresponding to human AMACR near the N-terminal.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_055139
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Antigen:
AMACR
Classification:
Polyclonal
Gene Accession No.:
Q9UHK6
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Applications:
Immunohistochemistry, Western Blot
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
AMACR
Immunogen:
GST-tagged recombinant protein corresponding to human AMACR near the N-terminal.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_055139
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Antigen: TRIM11
Classification: Polyclonal
Gene Accession No.: Q96F44
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Applications: Immunohistochemistry (Paraffin), Western Blot
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: TRIM11; RNF92
Immunogen: KLH-conjugated linear peptide corresponding to human TRIM11.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_660215
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Antigen:
TRIM11
Classification:
Polyclonal
Gene Accession No.:
Q96F44
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Applications:
Immunohistochemistry (Paraffin), Western Blot
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
TRIM11; RNF92
Immunogen:
KLH-conjugated linear peptide corresponding to human TRIM11.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_660215
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Antigen: LDHB
Classification: Polyclonal
Gene Accession No.: P07195
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Applications: Immunohistochemistry (Paraffin), Western Blot
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: LDHB
Immunogen: KLH-conjugated linear peptide corresponding to human LDHB sequence from the C-terminal half.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_002291
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Antigen:
LDHB
Classification:
Polyclonal
Gene Accession No.:
P07195
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Applications:
Immunohistochemistry (Paraffin), Western Blot
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
LDHB
Immunogen:
KLH-conjugated linear peptide corresponding to human LDHB sequence from the C-terminal half.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_002291
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.