ABE179525UG
PAXX, Rabbit anti-Human, Polyclonal, Millipore Sigma™
Manufacturer: MilliporeSigma
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABE179525UG-Each-of-1 | In Stock | ₹ 16,456.61 |
ABE179525UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,456.61
GST (18%): ₹ 2,962.19
Total Price: ₹ 19,418.80
Antigen
PAXX
Classification
Polyclonal
Dilution
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected PAXX in human prostate, human tonsil, and human cervical cancer tissues.
Gene Alias
Protein PAXX;Paralog of XRCC4 and XLF;XRCC4-like small protein;C9orf142
Host Species
Rabbit
Molecular Weight of Antigen
∽22 kDa observed; 21.64 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity
25 μg
Research Discipline
Epigenetics & Nuclear Function
Test Specificity
This rabbit polyclonal antibody detects PAXX protein. It targets an epitope within 16 amino acids from the C-terminus region.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine, 0.15M NaCl, pH7.4 with 0.05% sodium azide.
Gene Symbols
C9orf142;PAXX;XLS
Immunogen
KLH-conjugated liner peptide corresponding to 16 amino acids from the C-terminus region of human Protein PAXX.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Isotype
IgG
Description
- Anti-PAXX, Cat
- No
- ABE1795, is a highly specific rabbit polyclonal antibody that targets PAXX (C9orf142) and has been tested for use in Immunohistochemistry (Paraffin) and Western Blotting
- Protein PAXX (UniProt: 9BUH6; also known as Paralog of XRCC4 and XLF, XRCC4-like small protein) is encoded by the C9orf142 (also known as PAXX, XLS) gene (Gene ID: 286257) in human
- PAXX is a newer member of XRCC4 superfamily that predominantly localizes to the nucleus and is shown to accumulate at sites of DNA damage generated by laser microirradiation
- It is involved in non-homologous end joining (NHEJ), a major pathway to repair double-strand breaks in DNA and may act as a scaffold required to stabilize the Ku heterodimer, composed of XRCC5/Ku80 and XRCC6/Ku70, at double-strand break sites where it promote the assembly and/or stability of the NHEJ machinery
- PAXX residues 1-113 form a head domain, which is structurally related to those of XRCC4, XLF and SAS6
- This is followed by a 31-amino-acid -helix, forming a coiled-coil with the other protomer to make a PAXX homodimer
- Two isoforms of PAXX have been described that are produced by alternative splicing
- (Ref.: Ochi, T., et al
- (2015)
- Science 347(6218); 185-188).
Compare Similar Items
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Antigen: PAXX
Classification: Polyclonal
Dilution: Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected PAXX in human prostate, human tonsil, and human cervical cancer tissues.
Gene Alias: Protein PAXX;Paralog of XRCC4 and XLF;XRCC4-like small protein;C9orf142
Host Species: Rabbit
Molecular Weight of Antigen: ∽22 kDa observed; 21.64 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 25 μg
Research Discipline: Epigenetics & Nuclear Function
Test Specificity: This rabbit polyclonal antibody detects PAXX protein. It targets an epitope within 16 amino acids from the C-terminus region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine, 0.15M NaCl, pH7.4 with 0.05% sodium azide.
Gene Symbols: C9orf142;PAXX;XLS
Immunogen: KLH-conjugated liner peptide corresponding to 16 amino acids from the C-terminus region of human Protein PAXX.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG
Antigen:
PAXX
Classification:
Polyclonal
Dilution:
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected PAXX in human prostate, human tonsil, and human cervical cancer tissues.
Gene Alias:
Protein PAXX;Paralog of XRCC4 and XLF;XRCC4-like small protein;C9orf142
Host Species:
Rabbit
Molecular Weight of Antigen:
∽22 kDa observed; 21.64 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
25 μg
Research Discipline:
Epigenetics & Nuclear Function
Test Specificity:
This rabbit polyclonal antibody detects PAXX protein. It targets an epitope within 16 amino acids from the C-terminus region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine, 0.15M NaCl, pH7.4 with 0.05% sodium azide.
Gene Symbols:
C9orf142;PAXX;XLS
Immunogen:
KLH-conjugated liner peptide corresponding to 16 amino acids from the C-terminus region of human Protein PAXX.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG
Antigen: SMUG1
Classification: Polyclonal
Dilution: __
Gene Alias: __
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 100 μg
Research Discipline: Epigenetics and Nuclear Function
Test Specificity: This polyclonal antibody detects SMUG1 in HeLa cell nuclear extract. It targets an epitope within 13 amino acids from the N-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Western Blot
Conjugate: Unconjugated
Formulation: __
Gene Symbols: SMUG1
Immunogen: KLH-conjugated linear peptide corresponding to 13 amino acids from the N-terminal region of human SMUG1.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: __
Antigen:
SMUG1
Classification:
Polyclonal
Dilution:
__
Gene Alias:
__
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
100 μg
Research Discipline:
Epigenetics and Nuclear Function
Test Specificity:
This polyclonal antibody detects SMUG1 in HeLa cell nuclear extract. It targets an epitope within 13 amino acids from the N-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Western Blot
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
SMUG1
Immunogen:
KLH-conjugated linear peptide corresponding to 13 amino acids from the N-terminal region of human SMUG1.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
__
Antigen: __
Classification: __
Dilution: __
Gene Alias: __
Host Species: __
Molecular Weight of Antigen: __
Quantity: __
Research Discipline: __
Test Specificity: __
Content And Storage: __
Applications: __
Conjugate: __
Formulation: __
Gene Symbols: __
Immunogen: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Target Species: __
Isotype: __
Antigen:
__
Classification:
__
Dilution:
__
Gene Alias:
__
Host Species:
__
Molecular Weight of Antigen:
__
Quantity:
__
Research Discipline:
__
Test Specificity:
__
Content And Storage:
__
Applications:
__
Conjugate:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Target Species:
__
Isotype:
__
Antigen: La-Related Protein 1
Classification: Polyclonal
Dilution: __
Gene Alias: __
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 25 μg
Research Discipline: Epigenetics and Nuclear Function
Test Specificity: __
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Formulation: __
Gene Symbols: LARP1,KIAA0731,LARP
Immunogen: KLH-conjugated linear peptide corresponding to 15 amino acids from the N-termnal half of huamn La-related protein 1.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: __
Antigen:
La-Related Protein 1
Classification:
Polyclonal
Dilution:
__
Gene Alias:
__
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
25 μg
Research Discipline:
Epigenetics and Nuclear Function
Test Specificity:
__
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
LARP1,KIAA0731,LARP
Immunogen:
KLH-conjugated linear peptide corresponding to 15 amino acids from the N-termnal half of huamn La-related protein 1.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
__