ABN1642MI

APP Rabbit anti-Mouse, Human, Polyclonal, MilliporeSigma™

Manufacturer: MilliporeSigma

Select a Size

Pack Size SKU Availability Price
Each of 1 ABN1642MI-Each-of-1 In Stock ₹ 37,453.03

ABN1642MI - Each of 1

₹ 37,453.03

In Stock

Quantity

1

Base Price: ₹ 37,453.03

GST (18%): ₹ 6,741.545

Total Price: ₹ 44,194.575

Antigen

APP

Classification

Polyclonal

Conjugate

Unconjugated

Host Species

Rabbit

Purification Method

Unpurified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This antiserum detects the N-terminal fragment of AEP-cleaved APP at residue 585 (585N), but not the C-terminal fragment (585C) or uncleaved APP. The 585 numbering is based on isoform APP695/PreA4 695 (UniProt P05067-4) sequence. Equivalent site is also present in isoforms APP770 (Asn660; P05067-1), L-APP677 (Asn567; P05067-3), L-APP696 (Asn586; P05067-5), APP714 (Asn604; P05067-6), L-APP733 (Asn623; P05067-7), APP751/PreA4 751 (Asn641; P05067-8), L-APP752 (Asn642; P05067-9), APP639 (Asn529; P05067-10), and isoform 11 (Asn636; P05067-11). Cleavage site is not present in APP305 (P05067-2).

Content And Storage

Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications

Western Blot, Immunohistochemistry

Concentration

Please refer to lot specific datasheet.

Gene Symbols

APP,A4,AD1

Immunogen

Synthetic peptide corresponding to the C-terminal end sequence of AEP-cleaved APP 585N fragment.

Quantity

100 μL

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_958817

Target Species

Mouse, Human

Form

Serum

Description

  • Anti-APP, AEP-cleaved (585N) is a highly specific rabbit polyclonal antibody that targets the N-terminal fragment of AEP-cleaved APP at residue 585 (585N) and has been tested in Immunohistochemistry and Western Blotting.

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MilliporeSigma

ABN1642MI

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Antigen:
APP

Classification:
Polyclonal

Conjugate:
Unconjugated

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This antiserum detects the N-terminal fragment of AEP-cleaved APP at residue 585 (585N), but not the C-terminal fragment (585C) or uncleaved APP. The 585 numbering is based on isoform APP695/PreA4 695 (UniProt P05067-4) sequence. Equivalent site is also present in isoforms APP770 (Asn660; P05067-1), L-APP677 (Asn567; P05067-3), L-APP696 (Asn586; P05067-5), APP714 (Asn604; P05067-6), L-APP733 (Asn623; P05067-7), APP751/PreA4 751 (Asn641; P05067-8), L-APP752 (Asn642; P05067-9), APP639 (Asn529; P05067-10), and isoform 11 (Asn636; P05067-11). Cleavage site is not present in APP305 (P05067-2).

Content And Storage:
Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications:
Western Blot, Immunohistochemistry

Concentration:
Please refer to lot specific datasheet.

Gene Symbols:
APP,A4,AD1

Immunogen:
Synthetic peptide corresponding to the C-terminal end sequence of AEP-cleaved APP 585N fragment.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_958817

Target Species:
Mouse, Human

Form:
Serum

Img

MilliporeSigma

ABN1643MI

--


Antigen:
APP

Classification:
Polyclonal

Conjugate:
Unconjugated

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This antiserum detects the N-terminal fragment of AEP-cleaved APP at residue 373 (373N), but not the C-terminal fragment (373C) or uncleaved APP. The 373 numbering is based on isoforms L-APP677 and APP695/PreA4 695 (UniProt P05067-3 and P05067-4). Equivalent site is also present in isoforms APP770 (Asn448; P05067-1), L-APP696 (Asn392; P05067-5), APP714 (Asn392; P05067-6), L-APP733 (Asn429; P05067-7), APP751/PreA4 751 (Asn429; P05067-8), L-APP752 (Asn448; P05067-9), APP639 (Asn317; P05067-10), and isoform 11 (Asn424; P05067-11). Cleavage site is not present in APP305 (P05067-2).

Content And Storage:
Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications:
Immunohistochemistry, Western Blot

Concentration:
Please refer to lot specific datasheet.

Gene Symbols:
APP,A4,AD1

Immunogen:
Synthetic peptide corresponding to the C-terminal end sequence of AEP-cleaved APP 373N fragment.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_958817

Target Species:
Mouse, Human

Form:
Serum

Img

MilliporeSigma

ABN1644MI

--


Antigen:
C9orf72 (short form)

Classification:
Polyclonal

Conjugate:
Unconjugated

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antibody specifically detects the short isoform (C9-S) of C9orf72 protein. It targets an epitope within 12 amino acids from the C-terminal region.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Applications:
Western Blot, Immunoprecipitation, Immunofluorescence, Immunohistochemistry

Concentration:
Please refer to lot specific datasheet.

Gene Symbols:
C9orf72

Immunogen:
KLH-conjugated linear peptide corresponding to 12 amino acids from the C-terminal of short isoform (C9-S) of human C9orf72 with terminal asparagine substituted with lysine.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_659442

Target Species:
Human

Form:
Purified

Img

MilliporeSigma™

ABN1646MI

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Antigen:
CDC42

Classification:
Polyclonal

Conjugate:
Unconjugated

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antibody is purified from an antiserum that has been shown to specifically detect recombinant human CDC42 brain isoform Cdc42-palm (UniProt P60953-1) with or without C188S mutation, but not the placenta isoform Cdc42-prenyl (UniProt P60953-2) by Western blotting analysis (Kang, R., et al. (2008). Nature. 456(7224):904-909). Note that the designation of CDC42 isoform 1 and 2 by Kang et al. (2008) is the exact opposite of that by UniProt P60953 (human) and P60766 (mouse), while both Kang et al. (2008) and UniProt Q8CFN2 (rat) designate the rat CDC42 brain isoform as isoform 2.

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications:
Western Blot

Concentration:
Please refer to lot specific datasheet.

Gene Symbols:
__

Immunogen:
Synthetic peptide corresponding to the C-terminal end sequence of mature human CDC42 brain isoform.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_426359

Target Species:
Human

Form:
__