AHR0231
INSR alpha Monoclonal Antibody (83-7), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | AHR0231-Each-of-1 | In Stock | ₹ 43,635.60 |
AHR0231 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,635.60
GST (18%): ₹ 7,854.408
Total Price: ₹ 51,490.008
Antigen
INSR alpha
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.
P06213
Gene Symbols
INSR
Immunogen
IM-9 lymphocytes followed by purified insulin receptor.
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Bovine, Human, Ovine, Porcine, Rabbit
Product Type
Antibody
Isotype
IgG1 κ
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone
83-7
Conjugate
Unconjugated
Gene
INSR
Gene Alias
4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
100008911, 3643, 396755, 408017, 443431
Content And Storage
4° C
Form
Liquid
Description
- This antibody is specific for IR and shows no cross-reactivity with insulin-like growth factor (IGF)-receptors
- The epitope for this monoclonal antibody is conformational and is located in exon 3
- Staining of formalin-fixed, paraffin tissues requires digestion of tissue sections with pepsin at 1mg/mL in Tris-HCl, pH 2.0, for 15 min at room temperature or 10 min at 37oC
- Recommended positive controls include IM-9 lymphocytes, placenta, or breast carcinoma
- Biological actions of insulin and IGF-1 are mediated by their respective cell surface receptor tyrosine kinases that regulate multiple signaling pathways through activation of a series of phosphorylation cascades
- The insulin receptor
- Insulin/IGF-1 binding to the extracellular domain leads to autophosphorylation of downstream target proteins
- These two receptors differ in sequence in regions that confer specificity for the designated ligand as well as in certain intracellular signaling domains, resulting in significant differences in the functional consequences of activation of each receptor
- Defects in IR are the cause of various insulin resistance syndromes and IGF-1R defects may cause some forms of growth retardation
- Both these signaling cascades are also important for the development of cancer.
Compare Similar Items
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Antigen: INSR alpha
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.: P06213
Gene Symbols: INSR
Immunogen: IM-9 lymphocytes followed by purified insulin receptor.
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Bovine, Human, Ovine, Porcine, Rabbit
Product Type: Antibody
Isotype: IgG1 κ
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: 83-7
Conjugate: Unconjugated
Gene: INSR
Gene Alias: 4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100008911, 3643, 396755, 408017, 443431
Content And Storage: 4° C
Form: Liquid
Antigen:
INSR alpha
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P06213
Gene Symbols:
INSR
Immunogen:
IM-9 lymphocytes followed by purified insulin receptor.
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Ovine, Porcine, Rabbit
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
83-7
Conjugate:
Unconjugated
Gene:
INSR
Gene Alias:
4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100008911, 3643, 396755, 408017, 443431
Content And Storage:
4° C
Form:
Liquid
Antigen: IL-6 Receptor
Classification: Monoclonal
Concentration: 2.3 mg/mL
Formulation: PBS with no preservative; pH 7.2
Gene Accession No.: P08887
Gene Symbols: IL6R
Immunogen: CHO cells transfected with cDNA produced from the gp80 IL-6 receptor mRNA.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: ELISA, Flow Cytometry
Clone: B-N12
Conjugate: Unconjugated
Gene: IL6R
Gene Alias: CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 3570
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
IL-6 Receptor
Classification:
Monoclonal
Concentration:
2.3 mg/mL
Formulation:
PBS with no preservative; pH 7.2
Gene Accession No.:
P08887
Gene Symbols:
IL6R
Immunogen:
CHO cells transfected with cDNA produced from the gp80 IL-6 receptor mRNA.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
ELISA, Flow Cytometry
Clone:
B-N12
Conjugate:
Unconjugated
Gene:
IL6R
Gene Alias:
CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
3570
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: S1P1
Classification: Polyclonal
Concentration: __
Formulation: PBS with 0.08% sodium azide
Gene Accession No.: O08530, P21453, P48303
Gene Symbols: S1PR1
Immunogen: Synthetic peptide corresponding to the C terminal region of the human EDG-1 protein.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: __
Conjugate: Unconjugated
Gene: S1PR1
Gene Alias: AI849002; CD antigen CD363; CD363; CD363 antigen; CHEDG1; D1S3362; ECGF1; EDG1; EDG-1; EDG1 (Edg1); Edg1; rhodopsin family G protein-coupled receptor; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation sphingolipid G-protein-coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; etID43307.22; Lpb1; Lysophospholipid receptor B1; S1p; S1P receptor 1; S1P receptor Edg-1; s1p1; S1PR1; sphingosine 1-phosphate receptor; sphingosine 1-phosphate receptor 1; sphingosine 1-phosphate receptor EDG1; Sphingosine 1-phosphate receptor Edg-1; sphingosine-1-phosphate receptor 1; wu:fb98f05
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 13609, 1901, 29733
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
S1P1
Classification:
Polyclonal
Concentration:
__
Formulation:
PBS with 0.08% sodium azide
Gene Accession No.:
O08530, P21453, P48303
Gene Symbols:
S1PR1
Immunogen:
Synthetic peptide corresponding to the C terminal region of the human EDG-1 protein.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
S1PR1
Gene Alias:
AI849002; CD antigen CD363; CD363; CD363 antigen; CHEDG1; D1S3362; ECGF1; EDG1; EDG-1; EDG1 (Edg1); Edg1; rhodopsin family G protein-coupled receptor; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation sphingolipid G-protein-coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; etID43307.22; Lpb1; Lysophospholipid receptor B1; S1p; S1P receptor 1; S1P receptor Edg-1; s1p1; S1PR1; sphingosine 1-phosphate receptor; sphingosine 1-phosphate receptor 1; sphingosine 1-phosphate receptor EDG1; Sphingosine 1-phosphate receptor Edg-1; sphingosine-1-phosphate receptor 1; wu:fb98f05
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
13609, 1901, 29733
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: TNFR2 (soluble)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.5mg/mL sodium azide; pH 7.4
Gene Accession No.: P20333
Gene Symbols: Tnfrsf1b
Immunogen: Purified recombinant human soluble TNF Receptor II.
Quantity: 500 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA
Clone: 897C2G9
Conjugate: Unconjugated
Gene: Tnfrsf1b
Gene Alias: CD120b; Etanercept; p75; p75 TNF receptor; p75 TNFR; p75TNFR; p80 TNF-alpha receptor; sCD120b; soluble CD120b; soluble TNFR1B variant 1; soluble TNFR2; sTNF R2; sTNFR 2; sTNFR2; TBP-2; TBPII; TNF receptor beta chain; TNF receptor superfamily member 1B; TNF-alphaR2; TNFalpha-R2; TNFBR; TNFR; TNFR II; Tnfr-1; TNFR1B; TNFR2; TNF-R2; Tnfr-2; TNF-R75; TNFR80; TNFRII; TNF-RII; TNF-R-II; TNFR-II; TNFRSF1B; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis factor receptor; tumor necrosis factor receptor 2; Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor superfamily member 1b, membrane form; tumor necrosis factor receptor superfamily, member 1B; tumor necrosis factor receptor type II; Tumor necrosis factor-binding protein 2
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7133
Content And Storage: 4° C
Form: Liquid
Antigen:
TNFR2 (soluble)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.5mg/mL sodium azide; pH 7.4
Gene Accession No.:
P20333
Gene Symbols:
Tnfrsf1b
Immunogen:
Purified recombinant human soluble TNF Receptor II.
Quantity:
500 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA
Clone:
897C2G9
Conjugate:
Unconjugated
Gene:
Tnfrsf1b
Gene Alias:
CD120b; Etanercept; p75; p75 TNF receptor; p75 TNFR; p75TNFR; p80 TNF-alpha receptor; sCD120b; soluble CD120b; soluble TNFR1B variant 1; soluble TNFR2; sTNF R2; sTNFR 2; sTNFR2; TBP-2; TBPII; TNF receptor beta chain; TNF receptor superfamily member 1B; TNF-alphaR2; TNFalpha-R2; TNFBR; TNFR; TNFR II; Tnfr-1; TNFR1B; TNFR2; TNF-R2; Tnfr-2; TNF-R75; TNFR80; TNFRII; TNF-RII; TNF-R-II; TNFR-II; TNFRSF1B; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis factor receptor; tumor necrosis factor receptor 2; Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor superfamily member 1b, membrane form; tumor necrosis factor receptor superfamily, member 1B; tumor necrosis factor receptor type II; Tumor necrosis factor-binding protein 2
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7133
Content And Storage:
4° C
Form:
Liquid