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AHZ0202

CDK4 Monoclonal Antibody (DCS-31), Invitrogen™

Manufacturer: Invitrogen

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Pack Size	SKU	Availability	Price
Each of 1	AHZ0202-Each-of-1	In Stock	₹ 38,159.76

AHZ0202 - Each of 1

₹ 38,159.76

In Stock

Quantity

Base Price: ₹ 38,159.76

GST (18%): ₹ 6,868.757

Total Price: ₹ 45,028.517

Antigen

CDK4

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

P11802, P30285, P35426

Gene Symbols

Cdk4

Immunogen

Purified recombinant cdk4 protein.

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunoprecipitation, Western Blot, Western Blot

Clone

DCS-31

Conjugate

Unconjugated

Gene

Cdk4

Gene Alias

Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34<PSK-J3>/cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

1019, 12567, 94201

Content And Storage

4° C

Form

Liquid

Description

This antibody reacts with an epitope at aa 16-35
Recommended positive controls include MAD109, LS174T, and PC12 cells
CDK4/cyclin D3 serine/threonine kinase is dimeric protein complex
CDK4 is a member of the cyclin-dependent protein kinase family and is involved in the control of cell proliferation during the G1 phase of cell cycle
CDK4 forms a complex with the D-type cyclins and is inhibited by p16 (cyclin-dependent kinase inhibitor-2)
CDK4 can mediate phosphorylation of the C-terminal region of Rb protein leading to an active transcriptional repression of E2F complex
CDC37 and HSP90 can preferentially associate with the fraction of CDK4 not bound to D-type cyclins
SMAD3 is a major physiologic substrate of the G1 cyclin-dependent kinases CDK4 and CDK2
Although CDK6 and CDK4 can both phosphorylate multiple residues in the Rb protein, they do so with different residue selectivity in vitro; CDK6 phosphorylates Thr821 while CDK4 phosphorylates Thr826 on Rb protein.

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Invitrogen

AHZ0202

Antigen:

CDK4

Classification:

Monoclonal

Concentration:

0.2 mg/mL

Formulation:

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:

P11802, P30285, P35426

Gene Symbols:

Cdk4

Immunogen:

Purified recombinant cdk4 protein.

Quantity:

500 μL

Primary or Secondary:

Primary

Target Species:

Human, Mouse, Rat

Product Type:

Antibody

Isotype:

IgG1

Applications:

Flow Cytometry, Immunoprecipitation, Western Blot, Western Blot

Clone:

DCS-31

Conjugate:

Unconjugated

Gene:

Cdk4

Gene Alias:

Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34<PSK-J3>/cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)

Host Species:

Mouse

Purification Method:

Protein G

Regulatory Status:

RUO

Gene ID (Entrez):

1019, 12567, 94201

Content And Storage:

4° C

Form:

Liquid

A2B Chem

AI00001

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__

A2B Chem

AI00004

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__

A2B Chem

AI00006

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__

CDK4 Monoclonal Antibody (DCS-31), Invitrogen™

Select a Size

Select a Size

Properties

Antigen

Classification

Concentration

Formulation

Gene Accession No.

Gene Symbols

Immunogen

Quantity

Primary or Secondary

Target Species

Product Type

Isotype

Applications

Clone

Conjugate

Gene

Gene Alias

Host Species

Purification Method

Regulatory Status

Gene ID (Entrez)

Content And Storage

Form

Description

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Show Difference

Invitrogen

A2B Chem

A2B Chem

A2B Chem