AMPA6739

Bestrophin 1 Monoclonal Antibody (E6-6), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 AMPA6739-Each-of-1 In Stock ₹ 47,956.38

AMPA6739 - Each of 1

₹ 47,956.38

In Stock

Quantity

1

Base Price: ₹ 47,956.38

GST (18%): ₹ 8,632.148

Total Price: ₹ 56,588.528

Antigen

Bestrophin 1

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O76090, O88870, Q8WMR7

Gene Symbols

BEST1

Immunogen

Synthetic peptide conjugated to KLH corresponding to the C-terminus of human Bestrophin 1 (KDHMDPYWALENRDEAHS) [Uniprot: O76090]

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Non-human Primate, Porcine

Product Type

Antibody

Isotype

IgG1 κ

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Proximity Ligation Assay, Western Blot

Clone

E6-6

Conjugate

Unconjugated

Gene

BEST1

Gene Alias

ARB; BEST; BEST 1; Best disease; best macular dystrophy; BEST1; Best1V1Delta2; bestrophin; bestrophin 1; Bestrophin1; Bestrophin-1; BMD; Bmd1; LOW QUALITY PROTEIN: bestrophin-1; mBest1; RP50; TU15B; vitelliform macular dystrophy (Best disease, bestrophin); vitelliform macular dystrophy 2 homolog; vitelliform macular dystrophy protein 2; Vitelliform macular dystrophy protein 2 homolog; VMD 2; Vmd2

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

24115, 397169, 483791, 7439

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • This antibody does not react with rat samples
  • Suggested positive control: Pig RPE (retinal Pigment Epithelium) whole cell extract
  • The retinal pigment epithelium (RPE) and choroid represent a differentiated system of the eye that sustains normal retinal health and function
  • Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision
  • The lipofuscin-like material in the macular area appears as a yellow mass like the yolk of an egg that later becomes darker and irregular in color, a process known as &quotescrambling the egg&quote
  • Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells
  • Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium
  • Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current
  • The human Bestrophin gene encodes a 585 amino acid protein.

Compare Similar Items

Show Difference

Img

Thermo Scientific

AMPA6739

--


Antigen:
Bestrophin 1

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O76090, O88870, Q8WMR7

Gene Symbols:
BEST1

Immunogen:
Synthetic peptide conjugated to KLH corresponding to the C-terminus of human Bestrophin 1 (KDHMDPYWALENRDEAHS) [Uniprot: O76090]

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate, Porcine

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Proximity Ligation Assay, Western Blot

Clone:
E6-6

Conjugate:
Unconjugated

Gene:
BEST1

Gene Alias:
ARB; BEST; BEST 1; Best disease; best macular dystrophy; BEST1; Best1V1Delta2; bestrophin; bestrophin 1; Bestrophin1; Bestrophin-1; BMD; Bmd1; LOW QUALITY PROTEIN: bestrophin-1; mBest1; RP50; TU15B; vitelliform macular dystrophy (Best disease, bestrophin); vitelliform macular dystrophy 2 homolog; vitelliform macular dystrophy protein 2; Vitelliform macular dystrophy protein 2 homolog; VMD 2; Vmd2

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
24115, 397169, 483791, 7439

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

AMPA6746

--


Antigen:
STEP

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.09% sodium azide

Gene Accession No.:
P35234, P54829, P54830

Gene Symbols:
PTPN5

Immunogen:
A synthetic peptide of STEP46 (amino acids 57-74: MCTPGCNEEGFGYLVSPR)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
23E5

Conjugate:
Unconjugated

Gene:
PTPN5

Gene Alias:
FLJ14427; Neural-specific protein-tyrosine phosphatase; protein tyrosine phosphatase, non-receptor type 5; protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched); protein-tyrosine phosphatase striatum-enriched; protein-tyrosine-phosphatase non-receptor 5; PTN5; PTP STEP; PTPN 5; PTPN5; PTPSTEP; STEP; STEP61; striatal-enriched protein tyrosine phosphatase; striatum-enriched protein-tyrosine phosphatase; Tyrosine-protein phosphatase non-receptor type 5

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
19259, 29644, 84867

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

AMPA6748

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Antigen:
HIP1

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.1% sodium azide

Gene Accession No.:
O00291, Q8VD75

Gene Symbols:
HIP1

Immunogen:
Human HIP1 (∽65 kDa)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bacteria, Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
1B11

Conjugate:
Unconjugated

Gene:
HIP1

Gene Alias:
2610109B09Rik; A930014B11Rik; E130315I21Rik; HIP I; hip1; HIP-1; HIP-I; huntingtin interacting protein 1; huntingtin-interacting protein 1; Huntingtin-interacting protein I; ILWEQ; Kiaa4113; mKIAA4113; SHON; SHONbeta; SHONgamma

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
215114, 3092

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

AMPA6750

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Antigen:
HIP1R

Classification:
Monoclonal

Concentration:
7.7 mg/mL

Formulation:
ascites with 0.1% sodium azide

Gene Accession No.:
O75146, Q9JKY5

Gene Symbols:
HIP1R

Immunogen:
Human HIP1r-TALIN Homology Region (57 kDa).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bacteria, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
1E1

Conjugate:
Unconjugated

Gene:
HIP1R

Gene Alias:
AA410023; HIP12; HIP-12; Hip1r; HIP1-related protein; HIP3; huntingtin interacting protein 1 related; huntingtin interacting protein 12; Huntingtin-interacting protein 12; huntingtin-interacting protein 1-related protein; ILWEQ; KIAA0655; mKIAA0655

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
29816, 81917, 9026

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid