APP4686

Phospho-alpha Synuclein (Ser129) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 APP4686-Each-of-1 In Stock ₹ 47,528.58

APP4686 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

Phospho-alpha Synuclein (Ser129)

Classification

Polyclonal

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

O55042, P37377, P37840

Gene Symbols

SNCA

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser129 of rat SNCA conjugated to KLH

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry, Western Blot

Conjugate

Unconjugated

Gene

SNCA

Gene Alias

Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20617, 29219, 6622

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • This antibody is predicted to react with bovine, canine, human, mouse and non-human primate based on 100% sequence homology
  • This antibody is specific for the ∽15 kDa alpha-synuclein protein phosophorylated at Ser129
  • Immunolabeling is blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide
  • Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein
  • These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking
  • Alpha- and beta-synuclein have been shown to selectively inhibit phospholipase D2, suggesting that they may also be involved in signaling pathways
  • Defects in the SNCA gene, which encodes alpha-synuclein, have been implicated in the pathogenesis of Parkinson's disease
  • Additionally, alpha-synuclein peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease
  • Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene
  • Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant and Dementia, Lewy Body.

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Thermo Scientific

APP4686

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Antigen:
Phospho-alpha Synuclein (Ser129)

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O55042, P37377, P37840

Gene Symbols:
SNCA

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser129 of rat SNCA conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
SNCA

Gene Alias:
Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20617, 29219, 6622

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

APP4689

--


Antigen:
Phospho-MUNC18 (Ser515)

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P61765

Gene Symbols:
Stxbp1

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser515 of rat STXBP2 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
Stxbp1

Gene Alias:
AI317162; AI326233; ANC18HA; EIEE4; FLJ37475; hUNC18; MGC146482; minisatellite 10g detected by probe MMS10; MMS10-G; Ms10g; MUNC18-1; Munc-18a; munc-18c; neuronal SEC1; NSEC1; n-sec1; NSEC1A; p67; Protein unc-18 homolog 1; protein unc-18 homolog A; rbSec1; Rb-sec1; rbSec1A; rbSec1B; rop; RP11-56D16.3; Sec1; Stxbp1; Sxtbp1; syntaxin binding protein 1; syntaxin-binding protein 1; UNC18; UNC-18 homolog; unc-18-1; Unc18-1; UNC18A; unc-18A; Unc18h

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25558

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

APP4691

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Antigen:
RAB3a

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P20336, P63011, P63012

Gene Symbols:
RAB3A

Immunogen:
Synthetic peptide corresponding to the N-terminal region of rat RAB3A conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
RAB3A

Gene Alias:
C18A3.6; RAB3; Rab3a; RAB3A, member RAS oncogene family; RAS-associated protein RAB3A; ras-related protein Rab-3A; ras-related protein Rab-3A-like protein; Ras-related small GTP binding protein 3A

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19339, 25531, 5864

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

APP4692

--


Antigen:
RPH3A

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P47709

Gene Symbols:
RPH3A

Immunogen:
Synthetic peptide corresponding to the C-terminal region of rat RPH3A conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
RPH3A

Gene Alias:
2900002P20Rik; AU022689; AW108370; Exophilin 1; Exophilin1; Exophilin-1; KIAA0985; rabphilin 3A; rabphilin 3A homolog; rabphilin-3A; RPH3A

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171039

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid