APPA6598

DERL1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 APPA6598-Each-of-1 In Stock ₹ 44,191.74

APPA6598 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

DERL1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DERL1

Gene Alias

1110021N07Rik; AI195141; AW551338; Degradation in endoplasmic reticulum protein 1; DER1; DER-1; Der1-like domain family, member 1; der1-like protein 1; Derl1; derlin 1; derlin-1; DERtrin-1; RGD1311835; UNQ243/PRO276

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

103158862, 475086, 67819, 79139

Content And Storage

4° C, do not freeze

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

phosphate, tris citrate with 0.1% sodium azide; pH 7-8

Gene Accession No.

Q99J56, Q9BUN8

Gene Symbols

DERL1

Immunogen

Synthetic peptide corresponding to the C-terminal residues 200-251 of human Derlin-1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Canine, Hamster, Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with xenopus, bovine, chicken, rat, zebrafish, and mouse based on 100% sequence homology
  • Suggested positive control: antigen standard for DERL1 (transient overexpression lysate), KRM (canine microsome) lysates
  • Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins
  • May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome
  • May mediate the interaction between VCP and the degradation substrate
  • In case of infection by cytomegaloviruses, it plays a central role in the export from the ER and subsequent degradation of MHC class I heavy chains via its interaction with US11 viral protein, which recognizes and associates with MHC class I heavy chains
  • Also participates in the degradation process of misfolded cytomegalovirus US2 protein.

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APPA6598

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Antigen:
DERL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DERL1

Gene Alias:
1110021N07Rik; AI195141; AW551338; Degradation in endoplasmic reticulum protein 1; DER1; DER-1; Der1-like domain family, member 1; der1-like protein 1; Derl1; derlin 1; derlin-1; DERtrin-1; RGD1311835; UNQ243/PRO276

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
103158862, 475086, 67819, 79139

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
phosphate, tris citrate with 0.1% sodium azide; pH 7-8

Gene Accession No.:
Q99J56, Q9BUN8

Gene Symbols:
DERL1

Immunogen:
Synthetic peptide corresponding to the C-terminal residues 200-251 of human Derlin-1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Hamster, Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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APPA6601

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Antigen:
HIF1A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HIF1A

Gene Alias:
AA959795; ARNT interacting protein; ARNT2; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; bHLHe78; Class E basic helix-loop-helix protein 78; HIF; hif 1; hif 1a; HIF1; HIF1 alpha; HIF-1 alpha; HIF1a; hif-1a; hif1a.L; HIF1alpha; HIF-1alpha; HIF-1-alpha; HIF1-alpha; HIF1-alpha protein; hypoxia inducible factor 1 alpha; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1 alpha subunit L homeolog; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1 subunit alpha L homeolog; hypoxia inducible factor 1, alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor-1 alpha; hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1 alpha subunit; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) L homeolog; hypoxia-inducible factor 1-alpha; hypoxia-inducible factor-1 alpha; hypoxia-inducible factor1alpha; member of PAS protein 1; member of PAS superfamily 1; MOP1; PAS domain-containing protein 8; PASD8; XELAEV_18039792mg; XELAEV_18041137mg; xhif1a

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100009579, 100751293, 100861391, 15251, 29560, 3091, 396696, 480348

Content And Storage:
-20°C

Form:
Liquid

Applications:
ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O35800, Q16665, Q61221

Gene Symbols:
HIF1A

Immunogen:
A fusion protein including residues 530-825 of the mouse HIF-1 alpha protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Fish, Goat, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG

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APPA6604

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Antigen:
PINK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PINK1

Gene Alias:
1190006F07Rik; AU042772; AW557854; BRPK; FLJ27236; mFLJ00387; PARK6; PINK 1; Pink1; PINK-1; protein kinase BRPK; PTEN induced putative kinase 1; PTEN-induced putative kinase protein 1; Serine/threonine-protein kinase PINK1, mitochondrial

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
298575, 65018, 68943

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
tris citrate, tris phosphate with 0.1% sodium azide; pH 7-8

Gene Accession No.:
B5DFG1, Q99MQ3, Q9BXM7

Gene Symbols:
PINK1

Immunogen:
Synthetic peptide corresponding to the N-terminal residues 1-50 of human PINK1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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APPA6613

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Antigen:
VEGF Receptor 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KDR

Gene Alias:
6130401C07; CD309; CD309 antigen; fetal liver kinase 1; fetal liver kinase-1; FLK1; Flk-1; FLK1 kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGF receptor 2); FLK1 kinase insert domain receptor (VEGF receptor 2); flk-1 type VEGF receptor; KDR; kinase insert domain protein receptor; kinase insert domain receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); kinase NYK; Krd-1; Ly73; protein-tyrosine kinase receptor flk-1; sCD309; soluble CD309; soluble vascular endothelial growth factor receptor 2; soluble VEGFR 2; soluble VEGFR2; sVEGFR-2; tyrosine kinase growth factor receptor; vascular endotheial growth factor 2; vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor- 2; vascular endothelial growth factor receptor-2; vascular endothelial growth factor receptor-3; VEGF R2; VEGF receptor-2; VEGFR; VEGFR2; VEGFR-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16542, 3791

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.0 mg/mL

Formulation:
tris glycine with 0.15M NaCl and 0.05% sodium azide

Gene Accession No.:
P35918, P35968

Gene Symbols:
KDR

Immunogen:
A synthetic peptide made to an internal region of the murine VEGFR2 protein sequence (between residues 1200-1300).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG