APSA6557

DNMT3A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 APSA6557-Each-of-1 In Stock ₹ 47,443.02

APSA6557 - Each of 1

₹ 47,443.02

In Stock

Quantity

1

Base Price: ₹ 47,443.02

GST (18%): ₹ 8,539.744

Total Price: ₹ 55,982.764

Antigen

DNMT3A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DNMT3A

Gene Alias

AU015806; DNA (cytosine-5-)-methyltransferase 3 alpha; DNA (cytosine-5)-methyltransferase 3A; DNA cytosine methyltransferase 3A2; DNA methyltransferase 3 alpha; DNA methyltransferase 3A; DNA methyltransferase HsaIIIA; DNA methyltransferase MmuIIIA; DNA MTase HsaIIIA; DNA MTase MmuIIIA; Dnmt3a; DNMT3A2; M.HsaIIIA; MmuIIIA; TBRS; W91664

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum with 0.1% sodium azide

Gene Accession No.

O88508, Q9Y6K1

Gene Symbols

DNMT3A

Immunogen

This antibody was raised against amino acids 10-118 of the human DNMT3a protein.

Regulatory Status

RUO

Gene ID (Entrez)

13435, 1788

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody does not neutralize the enzymatic activity of its corresponding methyltransferase
  • Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended
  • Suggested positive control: antigen standard for DNMT3A (transient overexpression lysate), HCT116 cell lysates
  • Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development
  • Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer
  • To date, 3 families of mammalian DNA methyltransferase genes have been identified which include Dnmt1, Dnmt2 and Dnmt3
  • Dnmt1 is constitutively expressed in proliferating cells and inactivation of this gene causes global demethylation of genomic DNA and embryonic lethality
  • Dnmt2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation
  • The Dnmt3 family members, Dnmt3a and Dnmt3b, are strongly expressed in ES cells but their expression is down regulated in differentiating ES cells and is low in adult somatic tissue
  • Recently, it has been shown that naturally occurring mutations of Dnmt3b gene occurs in patients with a rare autosomal recessive disorder, termed ICF (immunodeficiency, centromeric instability, and facial anomalies) syndrome.

Compare Similar Items

Show Difference

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Thermo Scientific

APSA6557

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Antigen:
DNMT3A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNMT3A

Gene Alias:
AU015806; DNA (cytosine-5-)-methyltransferase 3 alpha; DNA (cytosine-5)-methyltransferase 3A; DNA cytosine methyltransferase 3A2; DNA methyltransferase 3 alpha; DNA methyltransferase 3A; DNA methyltransferase HsaIIIA; DNA methyltransferase MmuIIIA; DNA MTase HsaIIIA; DNA MTase MmuIIIA; Dnmt3a; DNMT3A2; M.HsaIIIA; MmuIIIA; TBRS; W91664

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.1% sodium azide

Gene Accession No.:
O88508, Q9Y6K1

Gene Symbols:
DNMT3A

Immunogen:
This antibody was raised against amino acids 10-118 of the human DNMT3a protein.

Regulatory Status:
RUO

Gene ID (Entrez):
13435, 1788

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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APSA6599

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Antigen:
VG5Q

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AGGF1

Gene Alias:
2010009L17Rik; 2310029P06Rik; AGGF1; Angiogenic factor VG5Q; angiogenic factor with G patch and FHA domains 1; angiogenic factor with G-patch and FHA domains 1; AW112072; FLJ10283; G patch domain-containing protein 7; GPATC7; GPATCH7; HSU84971; HUS84971; hVG5Q; mVG5Q; Peg3; RGD1310888; Vasculogenesis gene on 5q protein; Vg5q

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
Q8N302

Gene Symbols:
AGGF1

Immunogen:
A synthetic peptide mapping to an epitope within residues 500-600 of the human VG5Q protein.

Regulatory Status:
RUO

Gene ID (Entrez):
55109

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Thermo Scientific

APSA6600

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Antigen:
VG5Q

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AGGF1

Gene Alias:
2010009L17Rik; 2310029P06Rik; AGGF1; Angiogenic factor VG5Q; angiogenic factor with G patch and FHA domains 1; angiogenic factor with G-patch and FHA domains 1; AW112072; FLJ10283; G patch domain-containing protein 7; GPATC7; GPATCH7; HSU84971; HUS84971; hVG5Q; mVG5Q; Peg3; RGD1310888; Vasculogenesis gene on 5q protein; Vg5q

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
Q7TN31, Q8N302

Gene Symbols:
AGGF1

Immunogen:
A synthetic peptide mapping to an epitope within residues 300-400 of the murine VG5Q protein.

Regulatory Status:
RUO

Gene ID (Entrez):
55109, 66549

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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APSA6717

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Antigen:
Ubiquitin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPS27A

Gene Alias:
0610006J14Rik; 1810034D23Rik; 2700054O04Rik; 40S ribosomal protein S27a; 40S ribosomal protein S27-like; 40S ribosomal protein S27-like protein; AI194771; AL033289; CEP80; CG5271; CG5271-PA; Chap1; Dmel\CG5271; Dmel_CG5271; Dub80; epididymis luminal protein 112; epididymis secretory protein Li 50; HEL112; HEL-S-50; hm:zeh0386; HMG20; hPLIC-2; HRIHFB2157; HUBCEP52; ik:tdsubc_1f2; l(2)04820; l(2)31Ei; LOC100912032; LOC101747587; male female sterile 31; mfs(2)31; mfs(2)48; mfs48; OTTHUMP00000200786; OTTHUMP00000201692; PLIC-2; polyubiquitin; polyubiquitin B; polyubiquitin C; poly-ubiquitin precursor; polyubiquitin-B; Polyubiquitin-C; polyubiquitin-C-like; RE44350p; ribosomal protein S27; ribosomal protein S27 like; ribosomal protein S27A; ribosomal protein S27a L homeolog; ribosomal protein S27a S homeolog; ribosomal protein S27-like; ribosomal protein S27-like protein; RPL40; RpS27; Rps27a; rps27a.L; rps27a.S; RpS27A-PA; RPS27L; S27A; similar to polyubiquitin; similar to ubiquitin-S27a fusion protein; Small ribosomal subunit protein eS27-like; Small ribosomal subunit protein eS31; tdsubc_1f2; TI-225; UB3-D; Uba52; UBA80; UBB; Ubb2; UBC; UBCEP1; UBCEP80; Ubi-f80; Ubi-m; Ubiq; Ubiquilin 2; ubiquitin; ubiquitin (34 AA) (1 is 2nd base in codon); ubiquitin and ribosomal protein S27a; ubiquitin B; ubiquitin C; ubiquitin carboxyl extension protein 80; ubiquitin copy 4; ubiquitin fusion 80; ubiquitin polyprotein (heat shock related); ubiquitin/ribosomal protein; ubiquitin-40S ribosomal protein S27a; ubiquitin-40S ribosomal protein S27a-like; ubiquitin-CEP80; ubiquitin-hybrid protein precursor; Ubiquitin-monomeric; Ubiquitin-related; Ubiquitin-related 1; Ubiquitin-related 2; ubiquitin-S27a fusion protein; Unknown (protein for MGC:127652); unnamed protein product; XELAEV_18028796mg; xx:tdsubc_1f2; zgc:66168; zgc:66168 protein

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Proximity Ligation Assay, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 5mM sodium azide

Gene Accession No.:
P0CG47, P0CG48, P0CG49, P0CG50, P0CG51, P24051, P62979, P62982, P62983, P62984, P62986, P62987, Q63429, Q6ZWY3, Q71UM5

Gene Symbols:
RPS27A, RPS27L, UBA52, UBB, UBC

Immunogen:
Purified ubiquitin conjugated with glutaraldehyde to KLH

Regulatory Status:
RUO

Gene ID (Entrez):
100912032, 192255, 22186, 22187, 22190, 50522, 51065, 6233, 64156, 67941, 681429, 7311, 7314, 7316, 78294

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid